(Q33778905)

29 July 2017

The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation (English)

1 reference

29 July 2017

20

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29 July 2017

Nicolaos Palaskas

10

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Igor Vivanco

object named as

Igor Vivanco

1

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Ivan Đikić

object named as

Ivan Dikic

19

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Timothy F. Cloughesy

18

object named as

Timothy F Cloughesy

1 reference

29 July 2017

Daniel Rohle

2

1 reference

29 July 2017

Matthias Versele

3

1 reference

29 July 2017

Akio Iwanami

4

1 reference

29 July 2017

Daisuke Kuga

5

1 reference

29 July 2017

Barbara Oldrini

6

1 reference

29 July 2017

Kazuhiro Tanaka

7

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29 July 2017

Julie Dang

8

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29 July 2017

Sara Kubek

9

1 reference

29 July 2017

Teli Hsueh

11

1 reference

29 July 2017

Michael Evans

12

1 reference

29 July 2017

David Mulholland

13

1 reference

29 July 2017

Daniel Wolle

14

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29 July 2017

Sigrid Rajasekaran

15

1 reference

29 July 2017

Ayyappan Rajasekaran

16

1 reference

29 July 2017

Linda M Liau

17

1 reference

29 July 2017

Hong Wu

21

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29 July 2017

Paul S Mischel

22

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29 July 2017

Timothy Perera

23

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29 July 2017

Ingo K Mellinghoff

24

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29 July 2017

language of work or name

English

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publication date

22 March 2010

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

1 reference

29 July 2017

107

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29 July 2017

14

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29 July 2017

6459-6464

1 reference

Response prediction to a multitargeted kinase inhibitor in cancer cell lines and xenograft tumors using high-content tyrosine peptide arrays with a kinetic readout

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Transient potent BCR-ABL inhibition is sufficient to commit chronic myeloid leukemia cells irreversibly to apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Copy number gains in EGFR and copy number losses in PTEN are common events in osteosarcoma tumors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

A tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Epidermal growth factor receptors with tyrosine kinase domain mutations exhibit reduced Cbl association, poor ubiquitylation, and down-regulation but are efficiently internalized

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Update on epidermal growth factor receptor mutations in non-small cell lung cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Human cancer, PTEN and the PI-3 kinase pathway

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Escape from Cbl-mediated downregulation: a recurrent theme for oncogenic deregulation of receptor tyrosine kinases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Trafficking of the ErbB receptors and its influence on signaling

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2851999

Endocytosis and intracellular trafficking of ErbBs

4 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0911188107

Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0911188107

21 January 2018

Identifiers

DOI

10.1073/PNAS.0911188107

1 reference

29 July 2017

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1 reference

29 July 2017

1 reference