(Q33785790)

29 July 2017

title

A phase II trial of sorafenib in metastatic melanoma with tissue correlates (English)

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29 July 2017

main subject

phase II clinical trial

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1 reference

Patrick A Ott

1

1 reference

29 July 2017

Anne Hamilton

2

1 reference

29 July 2017

Christina Min

3

1 reference

29 July 2017

Sara Safarzadeh-Amiri

4

1 reference

29 July 2017

Lauren Goldberg

5

1 reference

29 July 2017

Joanne Yoon

6

1 reference

29 July 2017

Herman Yee

7

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29 July 2017

Michael Buckley

8

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29 July 2017

Paul J Christos

9

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29 July 2017

John J Wright

10

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29 July 2017

David Polsky

11

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29 July 2017

Iman Osman

12

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29 July 2017

Leonard Liebes

13

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29 July 2017

Anna C Pavlick

14

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29 July 2017

language of work or name

English

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publication date

29 December 2010

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29 July 2017

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29 July 2017

volume

5

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29 July 2017

issue

12

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29 July 2017

page(s)

e15588

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Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

29 December 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

Clinical responses observed with imatinib or sorafenib in melanoma patients expressing mutations in KIT

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).

28 July 2018

1 reference

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Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatin and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

Expression of sorafenib targets in melanoma patients treated with carboplatin, paclitaxel and sorafenib

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

Improving melanoma classification by integrating genetic and morphologic features

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

BRAF silencing by short hairpin RNA or chemical blockade by PLX4032 leads to different responses in melanoma and thyroid carcinoma cells

28 July 2018

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Major response to imatinib mesylate in KIT-mutated melanoma.

28 July 2018

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Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

28 July 2018

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Meta-analysis of phase II cooperative group trials in metastatic stage IV melanoma to determine progression-free and overall survival benchmarks for future phase II trials

28 July 2018

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Detection of mutant BRAF alleles in the plasma of patients with metastatic melanoma.

28 July 2018

1 reference

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Sorafenib in advanced clear-cell renal-cell carcinoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group

28 July 2018

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Somatic activation of KIT in distinct subtypes of melanoma

28 July 2018

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Sorafenib in advanced melanoma: a Phase II randomised discontinuation trial analysis

28 July 2018

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Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases

28 July 2018

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BAY 43-9006 inhibition of oncogenic RET mutants

28 July 2018

1 reference

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Distinct sets of genetic alterations in melanoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors

28 July 2018

1 reference

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

28 July 2018

1 reference

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B-RAF is a therapeutic target in melanoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

Mutations of the BRAF gene in human cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

Sorafenib in advanced hepatocellular carcinoma

28 July 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015588

Double-blind randomized phase II study of the combination of sorafenib and dacarbazine in patients with advanced melanoma: a report from the 11715 Study Group

21 January 2018

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Dose-dependent, complete response to imatinib of a metastatic mucosal melanoma with a K642E KIT mutation

21 January 2018

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RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015588

BRAF mutations in metastatic melanoma: a possible association with clinical outcome.

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

Analysis of BRAF and N-RAS mutations in metastatic melanoma tissues.

30 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

Cell cycle arrest and apoptosis of melanoma cells by docosahexaenoic acid: association with decreased pRb phosphorylation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012061

Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma

30 October 2018

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12 December 2020

Suppression of BRAF(V599E) in human melanoma abrogates transformation

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12 December 2020

Oncogenic BRAF is required for tumor growth and maintenance in melanoma models

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12 December 2020

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1 reference

12 December 2020

10.1371/JOURNAL.PONE.0015588

Identifiers

DOI

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29 July 2017

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29 July 2017

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