(Q33788720)

29 July 2017

title

Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome (English)

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29 July 2017

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Elizabeth M. C. Fisher

5

object named as

Elizabeth M C Fisher

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ORCID Public Data File 2021

29 July 2017

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author name string

Kate A Alford

1

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29 July 2017

Amy Slender

2

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29 July 2017

Lesley Vanes

3

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29 July 2017

Zhe Li

4

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29 July 2017

Dean Nizetic

6

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29 July 2017

Stuart H Orkin

7

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29 July 2017

Irene Roberts

8

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29 July 2017

Victor L J Tybulewicz

9

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29 July 2017

language of work or name

English

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publication date

12 February 2010

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29 July 2017

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29 July 2017

volume

115

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29 July 2017

issue

14

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29 July 2017

page(s)

2928-2937

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Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

ETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Trisomy 21 enhances human fetal erythro-megakaryocytic development

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Trisomy of chromosome 21 in leukemogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Role of GATA-1 in normal and neoplastic hemopoiesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Chromosome 21 and down syndrome: from genomics to pathophysiology

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

The management of neoplastic disorders of haematopoiesis in children with Down's syndrome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Transient abnormal myelopoiesis of infancy associated with trisomy 21.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Thrombocytopenia in neonates with trisomy 21.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Segmental trisomy of murine chromosome 16: a new model system for studying Down syndrome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

ERG is a megakaryocytic oncogene.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Abnormalities in the myeloid progenitor compartment in Down syndrome fetal liver precede acquisition of GATA1 mutations

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Hematological abnormalities during the first week of life among neonates with Down syndrome: data from a multihospital healthcare system

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Natural history of GATA1 mutations in Down syndrome

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Mouse models of Down syndrome: how useful can they be? Comparison of the gene content of human chromosome 21 with orthologous mouse genomic regions

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854435

Hematological abnormalities in newborn infants with Down syndrome

30 October 2018

1 reference

12 December 2020

Hematologic abnormalities in children with Down syndrome

1 reference

12 December 2020

Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1

1 reference

12 December 2020

Mutagenesis of GATA1 is an initiating event in Down syndrome leukemogenesis

1 reference

12 December 2020

Megakaryocyte hyperproliferation without GATA1 mutation in foetal liver of a case of Down syndrome with hydrops foetalis

1 reference

12 December 2020

Hematopoietic defects in the Ts1Cje mouse model of Down syndrome

1 reference

12 December 2020

10.1182/BLOOD-2009-06-227629

Identifiers

DOI

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29 July 2017

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29 July 2017

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