(Q33790000)

29 July 2017

title

Functional exofacially tagged N-type calcium channels elucidate the interaction with auxiliary α2δ-1 subunits (English)

1 reference

29 July 2017

5

1 reference

29 July 2017

Ivan Kadurin

3

0 references

author name string

John S Cassidy

series ordinal

1

1 reference

29 July 2017

Laurent Ferron

series ordinal

2

1 reference

29 July 2017

Wendy S Pratt

series ordinal

4

1 reference

29 July 2017

language of work or name

English

0 references

publication date

2 June 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

1 reference

29 July 2017

volume

111

1 reference

29 July 2017

issue

24

1 reference

29 July 2017

page(s)

8979-8984

1 reference

Calcium currents are enhanced by α2δ-1 lacking its membrane anchor

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Calcium channel auxiliary α2δ and β subunits: trafficking and one step beyond

28 July 2018

1 reference

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α2δ expression sets presynaptic calcium channel abundance and release probability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

The alpha2delta ligand gabapentin inhibits the Rab11-dependent recycling of the calcium channel subunit alpha2delta-2.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

The alpha2delta subunits of voltage-gated calcium channels form GPI-anchored proteins, a posttranslational modification essential for function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Three-dimensional structure of CaV3.1: comparison with the cardiac L-type voltage-gated calcium channel monomer architecture

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

The increased trafficking of the calcium channel subunit alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the alpha2delta ligand pregabalin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Functional properties and modulation of extracellular epitope-tagged Ca(V)2.1 voltage-gated calcium channels.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Identification of the alpha2-delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

The calcium channel alpha2delta-2 subunit partitions with CaV2.1 into lipid rafts in cerebellum: implications for localization and function.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

The metal-ion-dependent adhesion site in the Von Willebrand factor-A domain of alpha2delta subunits is key to trafficking voltage-gated Ca2+ channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Interaction via a key tryptophan in the I-II linker of N-type calcium channels is required for beta1 but not for palmitoylated beta2, implicating an additional binding site in the regulation of channel voltage-dependent properties

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Structural requirement of the calcium-channel subunit alpha2delta for gabapentin binding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Modulation of human neuronal alpha 1E-type calcium channel by alpha 2 delta-subunit.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Influence of L-type Ca channel alpha 2/delta-subunit on ionic and gating current in transiently transfected HEK 293 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

The beta subunit increases Ca2+ currents and gating charge movements of human cardiac L-type Ca2+ channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Identification of three subunits of the high affinity omega-conotoxin MVIIC-sensitive Ca2+ channel

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Potentiation by the beta subunit of the ratio of the ionic current to the charge movement in the cardiac calcium channel.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Sequence and expression of mRNAs encoding the alpha 1 and alpha 2 subunits of a DHP-sensitive calcium channel

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Subunit structure of dihydropyridine-sensitive calcium channels from skeletal muscle

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Structural characterization of the dihydropyridine-sensitive calcium channel alpha 2-subunit and the associated delta peptides

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Subunit identification and reconstitution of the N-type Ca2+ channel complex purified from brain

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1403731111

Auxiliary subunits operate as a molecular switch in determining gating behaviour of the unitary N-type Ca2+ channel current in Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1403731111

The ducky mutation in Cacna2d2 results in altered Purkinje cell morphology and is associated with the expression of a truncated alpha 2 delta-2 protein with abnormal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1403731111

Beta-subunits promote the expression of Ca(V)2.2 channels by reducing their proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1403731111

Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1403731111

ORL1 receptor-mediated internalization of N-type calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1403731111

Dual function of the voltage-dependent Ca2+ channel alpha 2 delta subunit in current stimulation and subunit interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1403731111

Anticonvulsant activity of pregabalin in the maximal electroshock-induced seizure assay in α2δ1 (R217A) and α2δ2 (R279A) mouse mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1403731111

Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Dissection of functional domains of the voltage-dependent Ca2+ channel alpha2delta subunit.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066493

Trafficking of L-type calcium channels mediated by the postsynaptic scaffolding protein AKAP79

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24889613

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Cavβ subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24889613

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1403731111

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference