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The specificity of trimming of MHC class I-presented peptides in the endoplasmic reticulum.
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Europe PubMed Central
PMC publication ID
2855122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
title
The specificity of trimming of MHC class I-presented peptides in the endoplasmic reticulum
(English)
1 reference
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Europe PubMed Central
PMC publication ID
2855122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
main subject
endoplasmic reticulum
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author
Ian A. York
series ordinal
2
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Europe PubMed Central
PMC publication ID
2855122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
author name string
Arron Hearn
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2855122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
Kenneth L Rock
series ordinal
3
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Europe PubMed Central
PMC publication ID
2855122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
language of work or name
English
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publication date
14 October 2009
1 reference
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Europe PubMed Central
PMC publication ID
2855122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
published in
Journal of Immunology
1 reference
stated in
Europe PubMed Central
PMC publication ID
2855122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
volume
183
1 reference
stated in
Europe PubMed Central
PMC publication ID
2855122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
issue
9
1 reference
stated in
Europe PubMed Central
PMC publication ID
2855122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
page(s)
5526-5536
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Europe PubMed Central
PMC publication ID
2855122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
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Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum.
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ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum
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Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance.
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4 July 2018
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A mutant cell with a novel defect in MHC class I quality control
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Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases
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Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I.
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4 July 2018
The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues
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An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides
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ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum
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PubMed Central
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The importance of the proteasome and subsequent proteolytic steps in the generation of antigenic peptides.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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4 July 2018
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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4 July 2018
The murine cytomegalovirus pp89 immunodominant H-2Ld epitope is generated and translocated into the endoplasmic reticulum as an 11-mer precursor peptide
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4 July 2018
26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide
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4 July 2018
Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells
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4 July 2018
Degradation of cell proteins and the generation of MHC class I-presented peptides
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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4 July 2018
Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses
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PubMed Central
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4 July 2018
Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase
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PubMed Central
reference URL
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4 July 2018
Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T cell responses to naturally processed peptides
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4 July 2018
Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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4 July 2018
Peptide size selection by the major histocompatibility complex-encoded peptide transporter
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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4 July 2018
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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4 July 2018
Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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4 July 2018
Chemistry of peptides associated with MHC class I and class II molecules
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4 July 2018
Herpes simplex virus turns off the TAP to evade host immunity
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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4 July 2018
Antigen processing in vivo and the elicitation of primary CTL responses
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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4 July 2018
Proline motifs in peptides and their biological processing
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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4 July 2018
The peptide-binding motif for the human transporter associated with antigen processing
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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4 July 2018
The 19-kDa glycoprotein coded by region E3 of adenovirus. Purification, characterization, and structural analysis.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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4 July 2018
In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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30 October 2018
The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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30 October 2018
Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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30 October 2018
Modeling the MHC class I pathway by combining predictions of proteasomal cleavage, TAP transport and MHC class I binding
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
retrieved
30 October 2018
Distinct proteolytic processes generate the C and N termini of MHC class I-binding peptides.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2855122
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30 October 2018
Monoclonal antibodies to mouse MHC antigens. II. Antibodies to the H-2Ld antigen, the products of a third polymorphic locus of the mouse major histocompatibility complex
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19828632
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transporter Associated with Antigen Processing Preselection of Peptides Binding to the MHC: A Bioinformatic Evaluation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19828632
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Monoclonal antibody to HLA-A3
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19828632
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Primary in vivo responses to ovalbumin. Probing the predictive value of the Kb binding motif
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19828632
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19828632
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4049/JIMMUNOL.0803663
1 reference
stated in
Europe PubMed Central
PMC publication ID
2855122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PMC publication ID
2855122
1 reference
stated in
Europe PubMed Central
PMC publication ID
2855122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
PubMed publication ID
19828632
1 reference
stated in
Europe PubMed Central
PMC publication ID
2855122
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19828632%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 February 2020
ResearchGate publication ID
38011111
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