(Q33804001)

29 July 2017

Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocyclic hexaoxazole (English)

1 reference

29 July 2017

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Hiroyuki Seimiya

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Takahiro Nakamura

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Sachiko Okabe

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Haruka Yoshida

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Keisuke Iida

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Yue Ma

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Shogo Sasaki

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Takao Yamori

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Ichiro Nakano

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Kazuo Nagasawa

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

English

0 references

publication date

15 June 2017

1 reference

29 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

3605

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

1 June 2020

copyright license

start time

15 June 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5472576/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/s41598-017-03785-8

0 references

cites work

G-quadruplex ligand-induced DNA damage response coupled with telomere dysfunction and replication stress in glioma stem cells

1 reference

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Cancer stem cells in glioblastoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472576

TRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation.

4 July 2018

1 reference

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Double-strand break repair: 53BP1 comes into focus

4 July 2018

1 reference

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Glioblastoma and other malignant gliomas: a clinical review.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472576

Evaluation of the interaction between long telomeric DNA and macrocyclic hexaoxazole (6OTD) dimer of a G-quadruplex ligand.

4 July 2018

1 reference

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A restricted cell population propagates glioblastoma growth after chemotherapy

4 July 2018

1 reference

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Small-molecule-induced DNA damage identifies alternative DNA structures in human genes

4 July 2018

1 reference

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Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb.

4 July 2018

1 reference

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Down-regulation of the human VEGF gene expression by perylene monoimide derivatives.

4 July 2018

1 reference

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A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472576

G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472576

Synthesis of Macrocyclic Hexaoxazole (6OTD) Dimers, Containing Guanidine and Amine Functionalized Side Chains, and an Evaluation of Their Telomeric G4 Stabilizing Properties

4 July 2018

1 reference

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Turning off transcription of the bcl-2 gene by stabilizing the bcl-2 promoter quadruplex with quindoline derivatives

4 July 2018

1 reference

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Potential therapeutic implications of cancer stem cells in glioblastoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472576

Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States.

4 July 2018

1 reference

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472576

Synthesis of a potent G-quadruplex-binding macrocyclic heptaoxazole

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472576

A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472576

Malignant gliomas in adults

4 July 2018

1 reference

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Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect

4 July 2018

1 reference

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Fluorescence-based melting assays for studying quadruplex ligands

4 July 2018

1 reference

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4 July 2018

Brain tumour stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472576

G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.

4 July 2018

1 reference

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Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas

4 July 2018

1 reference

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

4 July 2018

1 reference

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G-quartets 40 years later: from 5'-GMP to molecular biology and supramolecular chemistry

4 July 2018

1 reference

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Panel of human cancer cell lines provides valuable database for drug discovery and bioinformatics

4 July 2018

1 reference

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Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472576

Fluorescence resonance energy transfer as a probe for G-quartet formation by a telomeric repeat

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472576

Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472576

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472576

Exploring the formation and recognition of an important G-quadruplex in a HIF1α promoter and its transcriptional inhibition by a benzo[c]phenanthridine derivative.

4 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-03785-8

G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells

21 January 2018

1 reference

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Fluorescent-ligand-mediated screening of G-quadruplex structures using a DNA microarray.

21 January 2018

1 reference

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A caged ligand for a telomeric G-quadruplex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-03785-8

Visualization of G-quadruplexes by using a BODIPY-labeled macrocyclic heptaoxazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-03785-8

Macrocyclic hexaoxazoles as sequence- and mode-selective G-quadruplex binders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-03785-8

Stabilization of G-quadruplex DNA, inhibition of telomerase activity, and tumor cell apoptosis by organoplatinum(II) complexes with oxoisoaporphine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-03785-8

High-throughput sequencing of DNA G-quadruplex structures in the human genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41598-017-03785-8

Design and synthesis of unsymmetric macrocyclic hexaoxazole compounds with an ability to induce distinct G-quadruplex topologies in telomeric DNA

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28620243

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

G-quadruplex recognition by macrocyclic hexaoxazole (6OTD) dimer: greater selectivity than monomer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28620243

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/S41598-017-03785-8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28620243%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference