(Q33804626)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

title

A covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Silvano Piazza

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Marco Lolli

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Paola Storici

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Paolo Carloni

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Giulia Rossetti

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Federica Benvenuti

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Ezia Bello

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Maurizio D'Incalci

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Elisa Cappuzzello

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Antonio Rosato

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

author name string

Elena Campaner

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Alessandra Rustighi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Alberto Cristiani

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Yari Ciani

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Ori Kalid

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Gali Golan

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Erkan Baloglu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Sharon Shacham

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Barbara Valsasina

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Ulisse Cucchi

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Agnese Chiara Pippione

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Barbara Giabbai

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Giannino Del Sal

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

language of work or name

English

0 references

publication date

9 June 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

page(s)

15772

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

22 March 2020

copyright license

start time

9 June 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5472749/fullTextXML

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/5472749

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms15772

0 references

cites work

Glucocorticoid receptor signalling activates YAP in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

PIN1 in breast development and cancer: a clinical perspective.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Prolyl isomerases in gene transcription

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Prodrug applications for targeted cancer therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Structure-based virtual screening approach for discovery of covalently bound ligands

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Prolyl isomerase Pin1 acts downstream of miR200c to promote cancer stem-like cell traits in breast cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Pin1 inhibitors: Pitfalls, progress and cellular pharmacology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Identification of DNMT1 selective antagonists using a novel scintillation proximity assay

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

NIH Image to ImageJ: 25 years of image analysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Inhibitor mediated protein degradation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Slug and Sox9 cooperatively determine the mammary stem cell state

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Pin1 deficiency causes endothelial dysfunction and hypertension

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

The resurgence of covalent drugs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Cell death assays for drug discovery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

The prolyl isomerase Pin1 acts as a novel molecular switch for TNF-alpha-induced priming of the NADPH oxidase in human neutrophils

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Guidelines for the welfare and use of animals in cancer research

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Principles of cancer therapy: oncogene and non-oncogene addiction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

The epithelial-mesenchymal transition generates cells with properties of stem cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Extra precision glide: docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Insights into the catalytic mechanism of peptidyl prolyl cis/trans isomerases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Glide: a new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Molecular mechanisms of N-acetylcysteine actions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

PIN1 is an E2F target gene essential for Neu/Ras-induced transformation of mammary epithelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomerases by juglone.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease

28 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

Prolyl isomerase Pin1 in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

Pinning down HER2-ER crosstalk in SMRT regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

Prolyl isomerase Pin1 stabilizes and activates orphan nuclear receptor TR3 to promote mitogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

Modulation of oxidative stress as an anticancer strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

DNA damage by reactive species: Mechanisms, mutation and repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

Juglone inactivates cysteine-rich proteins required for progression through mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

Emerging strategies to effectively target autophagy in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

Radiotherapy-induced miR-223 prevents relapse of breast cancer by targeting the EGF pathway.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Semiautomated microtiter plate assay for monitoring peptidylprolyl cis/trans isomerase activity in normal and pathological human sera.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5472749

Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins

30 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

7 January 2021

inferred from DOI database lookup

Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15772

7 January 2021

inferred from DOI database lookup

Melatonin: Lowering the High Price of Free Radicals

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28598431

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCOMMS15772

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

22 March 2020

ADS bibcode

2017NatCo...815772C

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28598431%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PubMed publication ID

28598431

1 reference