(Q33810031)

29 July 2017

title

Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury (English)

1 reference

29 July 2017

0 references

1 reference

3

Raija Sormunen

1 reference

29 July 2017

7

Johanna Myllyharju

1 reference

29 July 2017

Jaana Hyvärinen

1

1 reference

29 July 2017

Ilmo E Hassinen

2

1 reference

29 July 2017

Joni M Mäki

4

1 reference

29 July 2017

Kari I Kivirikko

5

1 reference

29 July 2017

Peppi Koivunen

6

1 reference

29 July 2017

language of work or name

English

0 references

publication date

25 February 2010

1 reference

Journal of Biological Chemistry

29 July 2017

published in

1 reference

29 July 2017

volume

285

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29 July 2017

issue

18

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29 July 2017

page(s)

13646-13657

1 reference

A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo

29 July 2017

cites work

1 reference

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HIF prolyl 4-hydroxylases and their potential as drug targets

4 July 2018

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Regulation of oxygen homeostasis by hypoxia-inducible factor 1.

4 July 2018

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Mitochondria and reperfusion injury of the heart--a holey death but not beyond salvation

4 July 2018

1 reference

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Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains

4 July 2018

1 reference

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Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium

4 July 2018

1 reference

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Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

4 July 2018

1 reference

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Cardioprotection by hypoxia-inducible factor 1 alpha transfection in skeletal muscle is dependent on haem oxygenase activity in mice

4 July 2018

1 reference

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Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

4 July 2018

1 reference

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Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Short hairpin RNA interference therapy for ischemic heart disease

4 July 2018

1 reference

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Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy

4 July 2018

1 reference

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Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

4 July 2018

1 reference

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Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice

4 July 2018

1 reference

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Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice

4 July 2018

1 reference

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Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

An endoplasmic reticulum transmembrane prolyl 4-hydroxylase is induced by hypoxia and acts on hypoxia-inducible factor alpha

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

HIF-1 mediates the Warburg effect in clear cell renal carcinoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Cardioprotective actions of peptide hormones in myocardial ischemia.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Metabolic plasticity and the promotion of cardiac protection in ischemia and ischemic preconditioning

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

A conserved family of prolyl-4-hydroxylases that modify HIF

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Compensation for a gene trap mutation in the murine microtubule-associated protein 4 locus by alternative polyadenylation and alternative splicing

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Analysis of serial measurements in medical research

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2859527

Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1 alpha

4 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.084855

Hypoxia-inducible factor-1 is central to cardioprotection: a new paradigm for ischemic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.084855

Persistent induction of HIF-1alpha and -2alpha in cardiomyocytes and stromal cells of ischemic myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.084855

Apelin reduces myocardial reperfusion injury independently of PI3K/Akt and P70S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.084855

The effects of ischaemic preconditioning, diazoxide and 5-hydroxydecanoate on rat heart mitochondrial volume and respiration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.084855

Role of the reverse mode of the Na+/Ca2+ exchanger in reoxygenation-induced cardiomyocyte injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.084855

H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: A study with transgenic mice heterozygous for targeted disruption of the Heme oxygenase-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.084855

Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.084855

Hypoxia inducible factor regulates the cardiac expression and secretion of apelin

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20185832

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.084855

1 reference

29 July 2017

1 reference

29 July 2017

1 reference