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Mechanism of NLRP3 inflammasome activation
scientific article
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
24840700
retrieved
29 July 2017
title
Mechanism of NLRP3 inflammasome activation
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
24840700
retrieved
29 July 2017
main subject
inflammasome complex
1 reference
based on heuristic
inferred from title
author name string
Fayyaz S Sutterwala
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
24840700
retrieved
29 July 2017
Stefanie Haasken
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
24840700
retrieved
29 July 2017
Suzanne L Cassel
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
24840700
retrieved
29 July 2017
language of work or name
English
0 references
publication date
19 May 2014
1 reference
stated in
Europe PubMed Central
PubMed ID
24840700
retrieved
29 July 2017
published in
Annals of the New York Academy of Sciences
1 reference
stated in
Europe PubMed Central
PubMed ID
24840700
retrieved
29 July 2017
volume
1319
1 reference
stated in
Europe PubMed Central
PubMed ID
24840700
retrieved
29 July 2017
page(s)
82-95
1 reference
stated in
Europe PubMed Central
PubMed ID
24840700
retrieved
29 July 2017
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IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation.
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An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology
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28 July 2018
Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection
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28 July 2018
The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity
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28 July 2018
Cutting edge: Mouse NAIP1 detects the type III secretion system needle protein
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28 July 2018
Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome
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28 July 2018
Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome
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28 July 2018
Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation
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28 July 2018
K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter
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28 July 2018
Activation and regulation of the inflammasomes
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PubMed Central
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28 July 2018
The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation
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PubMed Central
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28 July 2018
TRPM2 links oxidative stress to NLRP3 inflammasome activation
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28 July 2018
Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
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28 July 2018
Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock
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28 July 2018
Deubiquitinases regulate the activity of caspase-1 and interleukin-1β secretion via assembly of the inflammasome
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28 July 2018
NLRP3 inflammasome activity is negatively controlled by miR-223.
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28 July 2018
Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1β production
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28 July 2018
Cell volume regulation modulates NLRP3 inflammasome activation
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28 July 2018
Inflammasomes and their roles in health and disease
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28 July 2018
Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation
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28 July 2018
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
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PubMed Central
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28 July 2018
An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages
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28 July 2018
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.
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28 July 2018
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
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28 July 2018
Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
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28 July 2018
Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice
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28 July 2018
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
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28 July 2018
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
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28 July 2018
A role for mitochondria in NLRP3 inflammasome activation
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28 July 2018
BID is cleaved by caspase-8 within a native complex on the mitochondrial membrane
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28 July 2018
Intracellular DNA recognition
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28 July 2018
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production
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28 July 2018
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
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28 July 2018
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
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28 July 2018
Cutting edge: TNF-alpha mediates sensitization to ATP and silica via the NLRP3 inflammasome in the absence of microbial stimulation
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28 July 2018
Immunological and inflammatory functions of the interleukin-1 family
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28 July 2018
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
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28 July 2018
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
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28 July 2018
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
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28 July 2018
Cardiolipin provides an essential activating platform for caspase-8 on mitochondria
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28 July 2018
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
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28 July 2018
The NLR gene family: a standard nomenclature
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28 July 2018
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
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28 July 2018
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
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28 July 2018
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
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28 July 2018
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses
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28 July 2018
Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1
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28 July 2018
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
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28 July 2018
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
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28 July 2018
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
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28 July 2018
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
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28 July 2018
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases
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28 July 2018
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
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28 July 2018
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
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28 July 2018
Two CD95 (APO-1/Fas) signaling pathways
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28 July 2018
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
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28 July 2018
An interaction between Bcl-xL and the voltage-dependent anion channel (VDAC) promotes mitochondrial Ca2+ uptake
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30 October 2018
The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation
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30 October 2018
Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors
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PubMed Central
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30 October 2018
Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.
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PubMed Central
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30 October 2018
Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1β.
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30 October 2018
The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.
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PubMed Central
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30 October 2018
Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction
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PubMed Central
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30 October 2018
Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1.
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PubMed Central
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30 October 2018
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074217
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30 October 2018
Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction
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PubMed Central
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30 October 2018
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection
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PubMed Central
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30 October 2018
NALP1 influences susceptibility to human congenital toxoplasmosis, proinflammatory cytokine response, and fate of Toxoplasma gondii-infected monocytic cells.
1 reference
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PubMed Central
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30 October 2018
Is mPTP the gatekeeper for necrosis, apoptosis, or both?
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30 October 2018
Critical functions of priming and lysosomal damage for NLRP3 activation
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PubMed Central
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30 October 2018
Signaling by ROS drives inflammasome activation
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30 October 2018
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
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30 October 2018
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
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30 October 2018
Role of phospholipid scramblase 3 in the regulation of tumor necrosis factor-alpha-induced apoptosis
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074217
retrieved
30 October 2018
Cytochrome c release from rat brain mitochondria is proportional to the mitochondrial functional deficit: implications for apoptosis and neurodegenerative disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074217
retrieved
30 October 2018
Early changes in intramitochondrial cardiolipin distribution during apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074217
retrieved
30 October 2018
Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074217
retrieved
30 October 2018
Cytochrome c release from mitochondria proceeds by a two-step process
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074217
retrieved
30 October 2018
Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074217
retrieved
30 October 2018
Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074217
retrieved
30 October 2018
Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24840700
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1111/NYAS.12458
1 reference
stated in
Europe PubMed Central
PubMed ID
24840700
retrieved
29 July 2017
Fatcat ID
release_fnvysm6xtzcjjcqmt3u2wevayu
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/fnvysm6xtzcjjcqmt3u2wevayu
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMCID
4074217
1 reference
stated in
Europe PubMed Central
PubMed ID
24840700
retrieved
29 July 2017
PubMed ID
24840700
1 reference
stated in
Europe PubMed Central
PubMed ID
24840700
retrieved
29 July 2017
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