(Q33822146)

English

2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Zachary J Reitman

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Zachary J Reitman

2

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Darell D. Bigner

7

object named as

Darell D Bigner

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Ines Batinic-Haberle

4

object named as

Ines Batinic-Haberle

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Genglin Jin

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Ivan Spasojevic

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Jian Yang

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Oleg Schmidt-Kittler

6

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Europe PubMed Central

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29 July 2017

Hai Yan

8

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Europe PubMed Central

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29 July 2017

language of work or name

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publication date

4 February 2011

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

6

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Europe PubMed Central

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29 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

e16812

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

copyright license

Creative Commons Attribution 4.0 International

4 February 2011

1 reference

April 2022 Public Data File from Crossref

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3033901/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

Mutant metabolic enzymes are at the origin of gliomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

Recurring mutations found by sequencing an acute myeloid leukemia genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

IDH1 and IDH2 mutations in gliomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

An integrated genomic analysis of human glioblastoma multiforme

1 reference

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4 July 2018

The consensus coding sequences of human breast and colorectal cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

Cellular concentrations of enzymes and their substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

Characterization of a cell line derived from a human oligodendroglioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033901

4 July 2018

Taxing sugar-sweetened beverages

1 reference

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21 January 2018

Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016812

21 January 2018

Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016812

21 January 2018

Measurement of urinary D- and L-2-hydroxyglutarate enantiomers by stable-isotope-dilution liquid chromatography-tandem mass spectrometry after derivatization with diacetyl-L-tartaric anhydride

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016812

21 January 2018

IDH1 mutations in gliomas: when an enzyme loses its grip

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016812

21 January 2018

Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms

1 reference

https://pubmed.ncbi.nlm.nih.gov/21326614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0016812

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

2011PLoSO...616812J

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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