(Q33825045)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24792928%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

PKCδ-IRAK1 axis regulates oxidized LDL-induced IL-1β production in monocytes (English)

1 reference

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17 March 2020

1

1 reference

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17 March 2020

author name string

Vishal Singh

2

1 reference

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17 March 2020

Ankita Singh

3

1 reference

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17 March 2020

Minakshi Rana

4

1 reference

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17 March 2020

Anupam Verma

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24792928%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Nikhil Kothari

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24792928%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Monica Kohli

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24792928%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Jaishri Bogra

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24792928%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Madhu Dikshit

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24792928%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Manoj Kumar Barthwal

10

1 reference

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17 March 2020

publication date

2 May 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24792928%20AND%20SRC:MED&resulttype=core&format=json

Journal of Lipid Research

17 March 2020

published in

1 reference

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17 March 2020

volume

55

1 reference

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17 March 2020

issue

7

1 reference

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17 March 2020

page(s)

1226-1244

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24792928%20AND%20SRC:MED&resulttype=core&format=json

OxLDL-induced IL-1 beta secretion promoting foam cells formation was mainly via CD36 mediated ROS production leading to NLRP3 inflammasome activation

17 March 2020

cites work

1 reference

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Pulmonary surfactant protein A and surfactant lipids upregulate IRAK-M, a negative regulator of TLR-mediated inflammation in human macrophages

4 July 2018

1 reference

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PKCδ signalling regulates SR-A and CD36 expression and foam cell formation.

4 July 2018

1 reference

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Trauma alarmins as activators of damage-induced inflammation

4 July 2018

1 reference

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Sterile inflammatory response in acute pancreatitis

4 July 2018

1 reference

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IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Protein kinase C and toll-like receptor signaling

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

IL-1R-associated kinase-1 mediates protein kinase Cδ-induced IL-1β production in monocytes.

4 July 2018

1 reference

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Vav guanine nucleotide exchange factors link hyperlipidemia and a prothrombotic state

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Circulating oxidized LDL and inflammation in extreme pediatric obesity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Oxidative modification of lipoproteins: mechanisms, role in inflammation and potential clinical applications in cardiovascular disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Sterile inflammation: sensing and reacting to damage

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

The activation of CD14, TLR4, and TLR2 by mmLDL induces IL-1β, IL-6, and IL-10 secretion in human monocytes and macrophages

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-δ (δ-PKC)

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Upregulation of TLR2/4 expression in mononuclear cells in postoperative systemic inflammatory response syndrome after liver transplantation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Origin and physiological roles of inflammation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

High glucose induces toll-like receptor expression in human monocytes: mechanism of activation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Oxidized LDL attenuates apoptosis in monocytic cells by activating ERK signaling

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Repeat organic dust exposure-induced monocyte inflammation is associated with protein kinase C activity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-delta knockout mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

A CD36-dependent signaling cascade is necessary for macrophage foam cell formation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Real-time PCR for mRNA quantitation

4 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

4 July 2018

https://api.crossref.org/works/10.1194%2FJLR.M045658

Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Distinctive activation mechanisms and functions for protein kinase Cdelta

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Src tyrosine kinase regulates insulin-induced activation of protein kinase C (PKC) delta in skeletal muscle

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Apoptotic pathways involved in U937 cells exposed to LDL oxidized by hypochlorous acid

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

High Glucose-Induced Expression of Proinflammatory Cytokine and Chemokine Genes in Monocytic Cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

IRAK-M is a negative regulator of Toll-like receptor signaling

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

IL-1-induced NFkappa B and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK)

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Oxidized LDL-induced NF-kappa B activation and subsequent expression of proinflammatory genes are defective in monocyte-derived macrophages from CD36-deficient patients

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Inhibition of human caspases by peptide-based and macromolecular inhibitors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Identification on human CD36 of a domain (155-183) implicated in binding oxidized low-density lipoproteins (Ox-LDL).

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Fragmentation of DNA in P388D1 macrophages exposed to oxidised low-density lipoprotein

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4076070

Novel PKC signaling is required for LPS-induced soluble Flt-1 expression in macrophages

4 July 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M045658

Increased myeloperoxidase enzyme activity in plasma is an indicator of inflammation and onset of sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M045658

Role of beta-adrenergic receptors in inflammatory marker expression in Müller cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M045658

Integrin alphaMbeta2 clustering triggers phosphorylation and activation of protein kinase C delta that regulates transcription factor Foxp1 expression in monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M045658

Involvement of protein kinase Cdelta and extracellular signal-regulated kinase-2 in the suppression of microglial inducible nitric oxide synthase expression by N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast).

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M045658

Quercetin regulates oxidized LDL induced inflammatory changes in human PBMCs by modulating the TLR-NF-κB signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M045658

Simple and cost-effective isolation of monocytes from buffy coats

21 January 2018

1 reference

12 December 2020

Rottlerin, a PKC isozyme-selective inhibitor, affects signaling events and cytokine production in human monocytes

1 reference

12 December 2020

Sequential flotation ultracentrifugation

1 reference

12 December 2020

Enhanced levels of oxidized low-density lipoprotein prime monocytes to cytokine overproduction via upregulation of CD14 and toll-like receptor 4 in unstable angina

1 reference

12 December 2020

Oxidized low-density lipoproteins inhibit endothelial cell proliferation by suppressing basic fibroblast growth factor expression

1 reference

12 December 2020

Activation of TLR2 and TLR4 by minimally modified low-density lipoprotein in human macrophages and monocytes triggers the inflammatory response

1 reference

12 December 2020

Levels of oxidized low-density lipoproteins are increased in patients with severe sepsis

1 reference

12 December 2020

Oxidized low-density lipoprotein induces secretion of interleukin-1β by macrophages via reactive oxygen species-dependent NLRP3 inflammasome activation

1 reference

12 December 2020

Combining sequential organ failure assessment (SOFA) score with acute physiology and chronic health evaluation (APACHE) II score to predict hospital mortality of critically ill patients

1 reference

12 December 2020

The role of NLRs and TLRs in the activation of the inflammasome

1 reference

12 December 2020

Synergism between protein-kinase C and cAMP-dependent pathways in the expression of the interleukin-1 beta gene is mediated via the activator-protein-1 (AP-1) enhancer activity

1 reference

12 December 2020

Oxidation-dependent effects of oxidized LDL: proliferation or cell death

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.M045658

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24792928%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24792928%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

1 reference