(Q44593868)

English

Involvement of protein kinase Cdelta and extracellular signal-regulated kinase-2 in the suppression of microglial inducible nitric oxide synthase expression by N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast).

scientific article published in October 2003

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Europe PubMed Central

PubMed publication ID

4 December 2017

Involvement of protein kinase Cdelta and extracellular signal-regulated kinase-2 in the suppression of microglial inducible nitric oxide synthase expression by N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast). (English)

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Europe PubMed Central

PubMed publication ID

4 December 2017

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inferred from title

Michael Platten

1

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4 December 2017

5

object named as

Michael Weller

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Europe PubMed Central

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4 December 2017

Jörg Wischhusen

3

object named as

Jörg Wischhusen

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4 December 2017

author name string

Katrin Eitel

2

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4 December 2017

Johannes Dichgans

4

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4 December 2017

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publication date

1 October 2003

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4 December 2017

Biochemical Pharmacology

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4 December 2017

66

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4 December 2017

7

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4 December 2017

1263-1270

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Europe PubMed Central

PubMed publication ID

4 December 2017

Microglia as mediators of inflammatory and degenerative diseases

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N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast) inhibits transforming growth factor-beta relesase and reduces migration and invasiveness of human malignant glioma cells

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7 January 2021

N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast) suppresses microglial inducible nitric oxide synthase (iNOS) expression and activity induced by interferon-gamma (IFN-gamma)

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Monokine production by microglial cell clones

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A novel lipopolysaccharide-response element contributes to induction of nitric oxide synthase

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Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures

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7 January 2021

Identification of protein kinase C isoforms involved in interferon-gamma-induced expression of inducible nitric oxide synthase in murine BV2 microglia

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7 January 2021

Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf.

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7 January 2021

Differential localization of protein kinase C delta by phorbol esters and related compounds using a fusion protein with green fluorescent protein

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7 January 2021

Rottlerin, a novel protein kinase inhibitor

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NF-kappaB in neuronal plasticity and neurodegenerative disorders

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Tranilast inhibits cytokine-induced nuclear factor kappaB activation in vascular endothelial cells

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7 January 2021

Macrophages derived from C3H/HeJ (Lpsd) mice respond to bacterial lipopolysaccharide by activating NF-kappa B.

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7 January 2021

Complex contribution of the 3'-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR.

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7 January 2021

Tranilast inhibits interleukin-1beta-induced monocyte chemoattractant protein-1 expression in rat mesangial cells

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7 January 2021

Inhibitory mechanism of tranilast in human coronary artery smooth muscle cells proliferation, due to blockade of PDGF-BB-receptors

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7 January 2021

Tranilast inhibits protein kinase C-dependent signalling pathway linked to angiogenic activities and gene expression of retinal microcapillary endothelial cells

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7 January 2021

Protein kinases C translocation responses to low concentrations of arachidonic acid

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7 January 2021

Three distinct mechanisms for translocation and activation of the delta subspecies of protein kinase C

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Protein kinase Cdelta activation by interleukin-1beta stabilizes inducible nitric-oxide synthase mRNA in pancreatic beta-cells

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7 January 2021

Identifiers

10.1016/S0006-2952(03)00449-0

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

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