(Q33829805)

29 July 2017

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title

Functional Genomic Insights into Regulatory Mechanisms of High-Altitude Adaptation (English)

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29 July 2017

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2

Zachary A Cheviron

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29 July 2017

Jay F Storz

1

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29 July 2017

language of work or name

English

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publication date

1 January 2016

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Advances in Experimental Medicine and Biology

29 July 2017

published in

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29 July 2017

volume

903

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29 July 2017

page(s)

113-128

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describes a project that uses

29 July 2017

common garden experiment

1 reference

inferred from PubMed Central ID database lookup

https://europepmc.org/article/PMC/5482796

Convergent Evolution of Hemoglobin Function in High-Altitude Andean Waterfowl Involves Limited Parallelism at the Molecular Sequence Level

20 June 2022

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Contribution of a mutational hot spot to hemoglobin adaptation in high-altitude Andean house wrens

4 July 2018

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Adaptive Modifications of Muscle Phenotype in High-Altitude Deer Mice Are Associated with Evolved Changes in Gene Regulation

4 July 2018

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High-altitude ancestry and hypoxia acclimation have distinct effects on exercise capacity and muscle phenotype in deer mice

4 July 2018

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Intraspecific polymorphism, interspecific divergence, and the origins of function-altering mutations in deer mouse hemoglobin.

4 July 2018

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Integrating evolutionary and functional tests of adaptive hypotheses: a case study of altitudinal differentiation in hemoglobin function in an Andean Sparrow, Zonotrichia capensis

4 July 2018

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A genetic mechanism for Tibetan high-altitude adaptation

4 July 2018

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Functional genomics of adaptation to hypoxic cold-stress in high-altitude deer mice: transcriptomic plasticity and thermogenic performance

4 July 2018

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4 July 2018

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Genomic analysis of natural selection and phenotypic variation in high-altitude Mongolians

4 July 2018

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4 July 2018

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Genetic signatures reveal high-altitude adaptation in a set of ethiopian populations

4 July 2018

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4 July 2018

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Phenotypic plasticity in blood-oxygen transport in highland and lowland deer mice

4 July 2018

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The genetic architecture of adaptations to high altitude in Ethiopia

4 July 2018

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Contributions of phenotypic plasticity to differences in thermogenic performance between highland and lowland deer mice

4 July 2018

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A critical assessment of storytelling: gene ontology categories and the importance of validating genomic scans.

4 July 2018

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Regulatory changes contribute to the adaptive enhancement of thermogenic capacity in high-altitude deer mice

4 July 2018

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Comparative genomics in ecological physiology: toward a more nuanced understanding of acclimation and adaptation

4 July 2018

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Experimental approaches to evaluate the contributions of candidate protein-coding mutations to phenotypic evolution

4 July 2018

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Altitudinal variation at duplicated β-globin genes in deer mice: effects of selection, recombination, and gene conversion.

4 July 2018

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Elevated performance: the unique physiology of birds that fly at high altitudes

4 July 2018

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RNA sequencing: advances, challenges and opportunities

4 July 2018

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Phenotypic plasticity and genetic adaptation to high-altitude hypoxia in vertebrates

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Genomic Differentiation Between Temperate and Tropical Australian Populations ofDrosophila melanogaster

4 July 2018

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Genetic Variations in Tibetan Populations and High-Altitude Adaptation at the Himalayas

4 July 2018

1 reference

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EGLN1 involvement in high-altitude adaptation revealed through genetic analysis of extreme constitution types defined in Ayurveda

4 July 2018

1 reference

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Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data

4 July 2018

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Genetic differences in hemoglobin function between highland and lowland deer mice

4 July 2018

1 reference

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Sequencing of 50 human exomes reveals adaptation to high altitude

4 July 2018

1 reference

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Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders

4 July 2018

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Integrating evolutionary and functional approaches to infer adaptation at specific loci

4 July 2018

1 reference

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Genetic evidence for high-altitude adaptation in Tibet

4 July 2018

1 reference

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Regulatory divergence in Drosophila revealed by mRNA-seq.

4 July 2018

1 reference

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Evolutionary and functional properties of a two-locus beta-globin polymorphism in Indian house mice

4 July 2018

1 reference

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Identifying positive selection candidate loci for high-altitude adaptation in Andean populations.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Stepwise modification of a modular enhancer underlies adaptation in a Drosophila population

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

The genetics of quantitative traits: challenges and prospects

4 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Systems genetics of complex traits in Drosophila melanogaster

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Is genetic evolution predictable?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Reverse engineering the genotype-phenotype map with natural genetic variation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

RNA-Seq: a revolutionary tool for transcriptomics

4 July 2018

1 reference

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Selective sweep at a quantitative trait locus in the presence of background genetic variation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Effects of spatially varying selection on nucleotide diversity and linkage disequilibrium: insights from deer mouse globin genes

4 July 2018

1 reference

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The loci of evolution: how predictable is genetic evolution?

4 July 2018

1 reference

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Evo-Devo and an Expanding Evolutionary Synthesis: A Genetic Theory of Morphological Evolution

4 July 2018

1 reference

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Mechanistic approaches to the study of evolution: the functional synthesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Moving toward a system genetics view of disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

The molecular basis of high-altitude adaptation in deer mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

The evolutionary significance of cis-regulatory mutations

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Convergent adaptation of human lactase persistence in Africa and Europe

4 July 2018

1 reference

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Genome-wide screening for cis-regulatory variation using a classical diallel crossing scheme

4 July 2018

1 reference

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Cis-transcriptional variation in maize inbred lines B73 and Mo17 leads to additive expression patterns in the F1 hybrid

4 July 2018

1 reference

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How reliable are empirical genomic scans for selective sweeps?

4 July 2018

1 reference

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Flying high: a theoretical analysis of the factors limiting exercise performance in birds at altitude

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Directional positive selection on an allele of arbitrary dominance

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Using genome scans of DNA polymorphism to infer adaptive population divergence

4 July 2018

1 reference

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Genetic variability at neutral markers, quantitative trait land trait in a subdivided population under selection

4 July 2018

1 reference

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Perspective: Evolutionary developmental biology and the problem of variation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Divergence of larval morphology between Drosophila sechellia and its sibling species caused by cis-regulatory evolution of ovo/shaven-baby

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Determinants of maximal oxygen transport and utilization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Biochemical and physiological correlates of deer mouse alpha-chain hemoglobin polymorphisms

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5482796

Detection of regulatory variation in mouse genes

4 July 2018

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https://api.crossref.org/works/10.1007%2F978-1-4899-7678-9_8

Cis and trans regulatory effects contribute to natural variation in transcriptome of Drosophila melanogaster

21 January 2018

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The evolution of gene regulation underlies a morphological difference between two Drosophila sister species.

21 January 2018

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Geographical variation in selection, from phenotypes to molecules.

21 January 2018

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Morphological evolution through multiple cis-regulatory mutations at a single gene.

21 January 2018

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Regulatory evolution of shavenbaby/ovo underlies multiple cases of morphological parallelism

21 January 2018

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Regulatory changes underlying expression differences within and between Drosophila species.

21 January 2018

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Identification of a Tibetan-specific mutation in the hypoxic gene EGLN1 and its contribution to high-altitude adaptation

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-1-4899-7678-9_8

A genome-wide search for signals of high-altitude adaptation in Tibetans

21 January 2018

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HEMOGLOBIN POLYMORPHISMS IN DEER MICE (PEROMYSCUS MANICULATUS): PHYSIOLOGY OF BETA-GLOBIN VARIANTS AND ALPHA-GLOBIN RECOMBINANTS.

21 January 2018

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Increased capacity for circulatory fatty acid transport in a highly aerobic mammal

29 October 2018

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12 December 2020

The signature of positive selection on standing genetic variation

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12 December 2020

Importance of fat as a support nutrient for energy: metabolism of athletes

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12 December 2020

Differentiation of allelic frequencies at quantitative trait loci affecting locally adaptive traits

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12 December 2020

10.1007/978-1-4899-7678-9_8

Identifiers

DOI

1 reference

29 July 2017

1 reference

29 July 2017

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