(Q33833630)

29 July 2017

The impact of multifunctional genes on "guilt by association" analysis (English)

1 reference

29 July 2017

Jesse Gillis

1

0 references

Paul Pavlidis

object named as

Paul Pavlidis

series ordinal

2

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language of work or name

English

0 references

publication date

18 February 2011

1 reference

29 July 2017

1 reference

29 July 2017

6

1 reference

29 July 2017

2

1 reference

29 July 2017

e17258

1 reference

Creative Commons Attribution 4.0 International

29 July 2017

start time

18 February 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Genome factor and gene pleiotropy hypotheses in protein evolution

4 July 2018

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Hub promiscuity in protein-protein interaction networks

4 July 2018

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The genetic landscape of a cell

4 July 2018

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KEGG for representation and analysis of molecular networks involving diseases and drugs

4 July 2018

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Evolution of biomolecular networks: lessons from metabolic and protein interactions

4 July 2018

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Influence of protein abundance on high-throughput protein-protein interaction detection

4 July 2018

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Protein promiscuity and its implications for biotechnology

4 July 2018

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High-throughput, quantitative analyses of genetic interactions in E. coli

4 July 2018

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AutDB: a gene reference resource for autism research

4 July 2018

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McKusick's Online Mendelian Inheritance in Man (OMIM)

4 July 2018

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InnateDB: facilitating systems-level analyses of the mammalian innate immune response.

4 July 2018

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Gene Ontology term overlap as a measure of gene functional similarity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Why do hubs in the yeast protein interaction network tend to be essential: reexamining the connection between the network topology and essentiality

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

GeneMANIA: a real-time multiple association network integration algorithm for predicting gene function

4 July 2018

1 reference

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A critical assessment of Mus musculus gene function prediction using integrated genomic evidence

4 July 2018

1 reference

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Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database

4 July 2018

1 reference

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Annotating genes of known and unknown function by large-scale coexpression analysis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Rank-based edge reconstruction for scale-free genetic regulatory networks

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Evidence of probabilistic behaviour in protein interaction networks

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Decoding genes with coexpression networks and metabolomics - 'majority report by precogs'.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

The BioGRID Interaction Database: 2008 update

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

An improved, bias-reduced probabilistic functional gene network of baker's yeast, Saccharomyces cerevisiae

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Assigning functions to genes--the main challenge of the post-genomics era.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

The human disease network

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Global protein expression profiling of budding yeast in response to DNA damage

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Evolutionary systems biology: links between gene evolution and function

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Finding function: evaluation methods for functional genomic data

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Evolutionary and physiological importance of hub proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

A global view of pleiotropy and phenotypically derived gene function in yeast

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Modularity and community structure in networks

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Choosing negative examples for the prediction of protein-protein interactions

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Toward a molecular understanding of pleiotropy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

MPact: the MIPS protein interaction resource on yeast

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Interactome: gateway into systems biology

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Analyzing protein function on a genomic scale: the importance of gold-standard positives and negatives for network prediction

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Coexpression analysis of human genes across many microarray data sets

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

A gene atlas of the mouse and human protein-encoding transcriptomes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Global mapping of the yeast genetic interaction network

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Stress-dependent nucleolin mobilization mediated by p53-nucleolin complex formation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Comparative assessment of large-scale data sets of protein-protein interactions

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Specificity and stability in topology of protein networks

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

On the shoulders of giants: p63, p73 and the rise of p53.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

DIP, the Database of Interacting Proteins: a research tool for studying cellular networks of protein interactions

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

A direct interaction between the survival motor neuron protein and p53 and its relationship to spinal muscular atrophy.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Lethality and centrality in protein networks

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

A network of protein-protein interactions in yeast

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Protein function in the post-genomic era.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

Gene ontology: tool for the unification of biology

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041792

4 July 2018

Multifunctional genes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017258

Pleiotropic scaling of gene effects and the 'cost of complexity'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017258

Gaining confidence in high-throughput protein interaction networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017258

Local coherence in genetic interaction patterns reveals prevalent functional versatility

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017258

Fast protein classification with multiple networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017258

Global protein function prediction from protein-protein interaction networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017258

Extreme self-organization in networks constructed from gene expression data.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017258

Predicting protein-protein interactions using signature products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017258

Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017258

Use of receiver operating characteristic (ROC) analysis to evaluate sequence matching.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017258

The Effect of Multifunctionality on the Rate of Evolution in Yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017258

Guilt-by-association goes global

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017258

Modularity and the cost of complexity

21 January 2018

1 reference

12 December 2020

ADAPTATION AND THE COST OF COMPLEXITY

1 reference

12 December 2020

Pleiotropic mutation, modularity and evolvability

1 reference

12 December 2020

Conservation and coevolution in the scale-free human gene coexpression network

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0017258

Identifiers

DOI

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference

PubMed ID

21364756