(Q33843457)

29 July 2017

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title

A new functional classification of tumor-suppressing genes and its therapeutic implications (English)

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29 July 2017

Islam MQ

1

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29 July 2017

Islam K

series ordinal

2

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29 July 2017

language of work or name

English

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publication date

1 March 2000

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29 July 2017

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29 July 2017

volume

22

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29 July 2017

issue

3

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29 July 2017

page(s)

274-285

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Suppression of Malignancy by Cell Fusion

29 July 2017

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Human tumor suppressor genes

21 January 2018

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Analysis of malignancy in human cells: malignant and transformed phenotypes are under separate genetic control

21 January 2018

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Monochromosome transfers to Syrian hamster BHK cells via microcell fusion provide functional evidence for suppressor genes on human chromosome 9 both for anchorage independence and for tumorigenicity

21 January 2018

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Mutation and cancer: statistical study of retinoblastoma

21 January 2018

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Human Cancer Syndromes: Clues to the Origin and Nature of Cancer

21 January 2018

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Genes in the RB pathway and their knockout in mice

21 January 2018

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Tumor suppressor gene mutations in mice

21 January 2018

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Tumor suppressor mutations in mice: the next generation

21 January 2018

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The p53-deficient mouse: a model for basic and applied cancer studies

21 January 2018

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Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

21 January 2018

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Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

21 January 2018

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Pten is essential for embryonic development and tumour suppression

21 January 2018

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CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

21 January 2018

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Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth

21 January 2018

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Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation.

21 January 2018

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Expression of a retinoblastoma transgene results in dwarf mice

21 January 2018

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Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

21 January 2018

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Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

21 January 2018

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Cooperation between oncogenes

21 January 2018

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Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts

21 January 2018

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Sustained nontumorigenic phenotype correlates with a largely stable chromosome content during long-term culture of the human keratinocyte line HaCaT.

21 January 2018

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Astrocytes derived from p53-deficient mice provide a multistep in vitro model for development of malignant gliomas

21 January 2018

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Further characterization of retinoblastoma gene-mediated cell growth and tumor suppression in human cancer cells

21 January 2018

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Differential elimination of 3p and retention of 3q segments in human/mouse microcell hybrids during tumor growth

21 January 2018

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Thymocyte apoptosis induced by p53-dependent and independent pathways.

21 January 2018

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p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

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Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

21 January 2018

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The murine gene p27Kip1 is haplo-insufficient for tumour suppression

21 January 2018

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Virtually 100% of melanoma cell lines harbor alterations at the DNA level within CDKN2A, CDKN2B, or one of their downstream targets

21 January 2018

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Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A

21 January 2018

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Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule

21 January 2018

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Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency.

21 January 2018

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Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat.

21 January 2018

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Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression

21 January 2018

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Evidence that wild-type TP53, and not genes on either chromosome 1 or 11, controls the tumorigenic phenotype of the human fibrosarcoma HT1080.

21 January 2018

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Senescence as a mode of tumor suppression

21 January 2018

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Tumor suppression and transcription elongation: the dire consequences of changing partners

21 January 2018

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Control of cell proliferation by Myc.

21 January 2018

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Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

21 January 2018

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New members of the Bcl-2 family and their protein partners

21 January 2018

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Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma

21 January 2018

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p21CIP1 and Cdc25A: competition between an inhibitor and an activator of cyclin-dependent kinases

21 January 2018

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Transducing Hedgehog: the story so far

21 January 2018

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

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The GDNF-RET signalling partnership

21 January 2018

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Hereditary cancer: two hits revisited

21 January 2018

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How viral oncogenes make the cell cycle

21 January 2018

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Inhibiting CDK inhibitors: new lessons from DNA tumor viruses

21 January 2018

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Adenovirus‐mediated gene transfer of wild‐type p53 results in melanoma cell apoptosis in vitro and in vivo

21 January 2018

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Induction of growth arrest and cell death by overexpression of the cyclin-Cdk inhibitor p21 in hamster BHK21 cells

21 January 2018

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Suppressor genes for malignant and anchorage-independent phenotypes located on human chromosome 9 have no dosage effects

21 January 2018

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Lack of tumor suppression but induced loss of copies of indigenous chromosome 10 in vitro following microcell-mediated transfer of a deleted human der(9)t(X;9) chromosome to Syrian hamster BHK-191-5C cells

21 January 2018

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Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group [published erratum appears in Hum Mol Genet 1998 May;7(5):941]

21 January 2018

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21 January 2018

Tumor suppressor genes

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Tumour-suppressor genes: evolving definitions in the genomic age

21 January 2018

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The INK4a/ARF tumor suppressor: one gene--two products--two pathways

21 January 2018

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Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys

21 January 2018

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Targeted in vivo expression of the cyclin-dependent kinase inhibitor p21 halts hepatocyte cell-cycle progression, postnatal liver development and regeneration

21 January 2018

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Nonrandom chromosomal changes in untreated retinoblastomas

21 January 2018

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Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1

21 January 2018

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Tumor suppression by chromosome 11 is not due to cellular senescence

21 January 2018

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Disomy and disease resolved?

21 January 2018

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Tumour suppressors and the regulation of GTP-binding protein activity

21 January 2018

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Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer

21 January 2018

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p27Kip1 overexpression causes apoptotic death of mammalian cells

21 January 2018

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Evidence for suppression of cellular growth in vitro and selection against the indigenous mouse X chromosome in A9 cell hybrids after microcell-mediated transfer of an X from other mammalian species

21 January 2018

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10.1002/(SICI)1521-1878(200003)22:3<274::AID-BIES9>3.0.CO;2-G

21 January 2018

Identifiers

DOI

1 reference

release_zyeskcqnrrbexeolsg2cwessoi

29 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zyeskcqnrrbexeolsg2cwessoi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference