(Q33845217)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

title

FBXW7 mutations in melanoma and a new therapeutic paradigm (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Rachel D Melamed

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Raúl Rabadán

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

8

Carlos Cordon-Cardo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Mireia Castillo-Martin

4

object named as

Mireia Castillo-Martin

1 reference

18 March 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

Sarah J Adams

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Ahu Demir

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Diana Bryk

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Georg Brunner

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Iman Osman

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

Julide Tok Celebi

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

language of work or name

English

0 references

publication date

16 May 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

Journal of the National Cancer Institute

18 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

volume

106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

page(s)

dju107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

SAVI: a statistical algorithm for variant frequency identification

18 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

The integrated landscape of driver genomic alterations in glioblastoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

5 July 2018

Cancer statistics, 2013

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

A landscape of driver mutations in melanoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Tumor suppressor functions of FBW7 in cancer development and progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Melanoma genome sequencing reveals frequent PREX2 mutations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Therapeutic antibody targeting of individual Notch receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Active Notch1 confers a transformed phenotype to primary human melanocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Melanoma biology and new targeted therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Mutations of the BRAF gene in human cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4081626

Fbw7 isoform interaction contributes to cyclin E proteolysis.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FJNCI%2FDJU107

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FJNCI%2FDJU107

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FJNCI%2FDJU107

High levels of expression of p27KIP1 and cyclin E in invasive primary malignant melanomas

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24838835

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/JNCI/DJU107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24838835%20AND%20SRC:MED&resulttype=core&format=json