(Q33848050)

English

EMSY overexpression disrupts the BRCA2/RAD51 pathway in the DNA-damage response: implications for chromosomal instability/recombination syndromes as checkpoint diseases

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

EMSY overexpression disrupts the BRCA2/RAD51 pathway in the DNA-damage response: implications for chromosomal instability/recombination syndromes as checkpoint diseases (English)

1 reference

Europe PubMed Central

29 July 2017

0 references

1 reference

based on heuristic

inferred from title

author name string

Isabelle Cousineau

1

1 reference

Europe PubMed Central

29 July 2017

Abdellah Belmaaza

2

1 reference

Europe PubMed Central

29 July 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

16 March 2011

1 reference

Europe PubMed Central

29 July 2017

Molecular Genetics and Genomics

1 reference

Europe PubMed Central

29 July 2017

285

1 reference

Europe PubMed Central

29 July 2017

325-340

1 reference

Europe PubMed Central

29 July 2017

4

1 reference

Europe PubMed Central

29 July 2017

copyright license

Creative Commons Attribution-NonCommercial 2.0 Generic

16 March 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1007/s00438-011-0612-5

0 references

PARP1 suppresses homologous recombination events in mice in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Single-molecule imaging brings Rad51 nucleoprotein filaments into focus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

PALB2 links BRCA1 and BRCA2 in the DNA-damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

ATR kinase is required for global genomic nucleotide excision repair exclusively during S phase in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

An oncogene-induced DNA damage model for cancer development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Regulation of DNA repair throughout the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

The DNA damage response: ten years after

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

BRCA2: a universal recombinase regulator.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

The Mre11 complex mediates the S-phase checkpoint through an interaction with replication protein A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Identification of primary transcriptional regulation of cell cycle-regulated genes upon DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

BRCA1 haploinsufficiency, but not heterozygosity for a BRCA1-truncating mutation, deregulates homologous recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Interplay of replication checkpoints and repair proteins at stalled replication forks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Chromatin challenges during DNA replication and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Essential role for nuclear PTEN in maintaining chromosomal integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Mouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

ATR-dependent phosphorylation of DNA-dependent protein kinase catalytic subunit in response to UV-induced replication stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

CeBRC-2 stimulates D-loop formation by RAD-51 and promotes DNA single-strand annealing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

BRCA1 regulates RAD51 function in response to DNA damage and suppresses spontaneous sister chromatid replication slippage: implications for sister chromatid cohesion, genome stability, and carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

The DNA damage response during DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Differential cellular responses to exogenous DNA in mammalian cells and its effect on oligonucleotide-directed gene modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Genomic instability of human mammary epithelial cells overexpressing a truncated form of EMSY.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Homologous recombination is involved in transcription-coupled repair of UV damage in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

BRCA2 regulates homologous recombination in response to DNA damage: implications for genome stability and carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Cell-cycle checkpoints and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Oncogenic pathways in hereditary and sporadic breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Cancer genes and the pathways they control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Double strand break repair by homologous recombination is regulated by cell cycle-independent signaling via ATM in human glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Dynamic control of Rad51 recombinase by self-association and interaction with BRCA2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

BARD1 participates with BRCA1 in homology-directed repair of chromosome breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

MSH2-deficient human cells exhibit a defect in the accurate termination of homology-directed repair of DNA double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Interaction between BRCA2 and replication protein A is compromised by a cancer-predisposing mutation in BRCA2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Homologous repair of DNA damage and tumorigenesis: the BRCA connection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

DNA double-strand break repair signalling: the case of RAD51 post-translational regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

DNA substrate dependence of p53-mediated regulation of double-strand break repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

RAG-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Cancer susceptibility and the functions of BRCA1 and BRCA2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Transcriptional interference by independently regulated genes occurs in any relative arrangement of the genes and is influenced by chromosomal integration position

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

The human decatenation checkpoint.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Promoter suppression in cultured mammalian cells can be blocked by the chicken beta-globin chromatin insulator 5'HS4 and matrix/scaffold attachment regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

In search of the tumour-suppressor functions of BRCA1 and BRCA2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

BRCA1 and BRCA2 are necessary for the transcription-coupled repair of the oxidative 8-oxoguanine lesion in human cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

The BRCA2 gene product functionally interacts with p53 and RAD51

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Cells deleted for Brca2 COOH terminus exhibit hypersensitivity to gamma-radiation and premature senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Regulation of Rad51 function by c-Abl in response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Chromosome instability syndromes: lessons for carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

One-sided invasion events in homologous recombination at double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

28 July 2018

Reduced ligation during DNA base excision repair supported by BRCA2 mutant cells

1 reference

https://api.crossref.org/works/10.1007%2FS00438-011-0612-5

21 January 2018

Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance.

1 reference

https://api.crossref.org/works/10.1007%2FS00438-011-0612-5

21 January 2018

Location of tyrosine 315, a target for phosphorylation by cAbl tyrosine kinase, at the edge of the subunit-subunit interface of the human Rad51 filament

1 reference

https://api.crossref.org/works/10.1007%2FS00438-011-0612-5

21 January 2018

Oncogenes and the DNA damage response: Myc and E2F1 engage the ATM signaling pathway to activate p53 and induce apoptosis.

1 reference

https://api.crossref.org/works/10.1007%2FS00438-011-0612-5

21 January 2018

Disruption of p53 by the viral oncoprotein HPV16-E6 does not deregulate chromosomal homologous recombination in a transcriptional interference-free assay system.

1 reference

https://api.crossref.org/works/10.1007%2FS00438-011-0612-5

21 January 2018

DNA binding, annealing, and strand exchange activities of Brh2 protein from Ustilago maydis

1 reference

https://api.crossref.org/works/10.1007%2FS00438-011-0612-5

21 January 2018

ATM and related protein kinases: safeguarding genome integrity

1 reference

https://api.crossref.org/works/10.1007%2FS00438-011-0612-5

21 January 2018

Physical interaction between replication protein A and Rad51 promotes exchange on single-stranded DNA.

1 reference

https://api.crossref.org/works/10.1007%2FS00438-011-0612-5

21 January 2018

Ten genes for inherited breast cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS00438-011-0612-5

21 January 2018

Aneuploidy acts both oncogenically and as a tumor suppressor

1 reference

https://api.crossref.org/works/10.1007%2FS00438-011-0612-5

21 January 2018

Conspiracy of silence among repeated transgenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064890

29 October 2018

Defective S phase chromatin assembly causes DNA damage, activation of the S phase checkpoint, and S phase arrest

1 reference

https://pubmed.ncbi.nlm.nih.gov/21409565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The processing of DNA ends at double-strand breaks during homologous recombination: different roles for the two ends

1 reference

https://pubmed.ncbi.nlm.nih.gov/21409565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7

1 reference

https://pubmed.ncbi.nlm.nih.gov/21409565

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00438-011-0612-5

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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