(Q33853215)

29 July 2017

1 reference

title

Multiple functions of p27(Kip1) and its alterations in tumor cells: a review (English)

1 reference

29 July 2017

Sgambato A

1

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29 July 2017

Cittadini A

series ordinal

2

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29 July 2017

Faraglia B

series ordinal

3

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29 July 2017

Weinstein IB

series ordinal

4

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29 July 2017

publication date

1 April 2000

1 reference

Journal of Cellular Physiology

29 July 2017

published in

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29 July 2017

volume

183

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29 July 2017

issue

1

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29 July 2017

page(s)

18-27

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Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

29 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Overexpressed cyclin D3 contributes to retaining the growth inhibitor p27 in the cytoplasm of thyroid tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Increased level of p21 in human ovarian tumors is associated with increased expression of cdk2, cyclin A and PCNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Tumor suppression and inhibition of aneuploid cell accumulation in human brain tumor cells by ectopic overexpression of the cyclin-dependent kinase inhibitor p27KIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

A recombinant adenovirus expressing p27Kip1 induces cell cycle arrest and loss of cyclin-Cdk activity in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Increased expression of the P27KIP1 protein in human esophageal cancer cell lines that over-express cyclin D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Cdk inhibitors: on the threshold of checkpoints and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

p27Kip1 induces drug resistance by preventing apoptosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Dependence of cyclin E-CDK2 kinase activity on cell anchorage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Translational control of p27Kip1 accumulation during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

RhoA stimulates p27(Kip) degradation through its regulation of cyclin E/CDK2 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Molecular analysis of p21 and p27 genes in human pituitary adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Expression of the v-Src oncoprotein in fibroblasts disrupts normal regulation of the CDK inhibitor p27 and inhibits quiescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Role of p27Kip1 and cyclin-dependent kinase 2 in the proliferation of non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Inhibition of cyclin-dependent kinase activity triggers neuronal differentiation of mouse neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Cyclins, cyclin-dependent kinases and cdk inhibitors: implications in cell cycle control and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFbeta-treated cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Principles of CDK regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Expression of the cell cycle inhibitor p27KIP1 is a new prognostic marker associated with survival in epithelial ovarian tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Cytoplasmic displacement of cyclin E-cdk2 inhibitors p21Cip1 and p27Kip1 in anchorage-independent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Proteasome-dependent degradation of p27/kip1 in gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Activated Raf-1 causes growth arrest in human small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Comparison of the effectiveness of adenovirus vectors expressing cyclin kinase inhibitors p16INK4A, p18INK4C, p19INK4D, p21(WAF1/CIP1) and p27KIP1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

G1 phase progression: cycling on cue

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Inhibitors of mammalian G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Inactivation of the cyclin-dependent kinase inhibitor p27 upon loss of the tuberous sclerosis complex gene-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Ras activity late in G1 phase required for p27kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

The cyclin-dependent kinase inhibitor p27Kip1 is localized to the cytosol in Swiss/3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Comparative effects of overexpression of p27Kip1 and p21Cip1/Waf1 on growth and differentiation in human colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is associated with advanced stage and invasiveness of gastric carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291097-4652%28200004%29183%3A1%3C18%3A%3AAID-JCP3%3E3.0.CO%3B2-S

10.1002/(SICI)1097-4652(200004)183:1<18::AID-JCP3>3.0.CO;2-S

21 January 2018

Identifiers

DOI

1 reference

29 July 2017

1 reference