(Q33854289)

29 July 2017

title

Diclofenac inhibits tumor necrosis factor-α-induced nuclear factor-κB activation causing synergistic hepatocyte apoptosis (English)

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29 July 2017

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12

Bob van de Water

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Erik Danen

object named as

Erik Danen

10

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author name string

Lisa Fredriksson

1

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29 July 2017

Bram Herpers

2

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29 July 2017

Giulia Benedetti

3

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29 July 2017

Quraisha Matadin

4

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29 July 2017

Jordi C Puigvert

5

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29 July 2017

Hans de Bont

6

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29 July 2017

Sanja Dragovic

7

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29 July 2017

Nico P E Vermeulen

8

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29 July 2017

Jan N M Commandeur

9

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29 July 2017

Marjo de Graauw

11

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29 July 2017

Bob van de Water

12

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29 July 2017

language of work or name

English

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publication date

1 June 2011

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29 July 2017

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29 July 2017

volume

53

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29 July 2017

issue

6

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29 July 2017

page(s)

2027-2041

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Etiologies of acute liver failure

29 July 2017

cites work

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Nonsteroidal anti-inflammatory drug-induced hepatotoxicity

21 January 2018

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Systematic review: the lower gastrointestinal adverse effects of non-steroidal anti-inflammatory drugs

21 January 2018

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Idiosyncratic toxicity: a convergence of risk factors

21 January 2018

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Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity

21 January 2018

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Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis

21 January 2018

1 reference

Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha.

21 January 2018

1 reference

Bacterial lipopolysaccharide enhances aflatoxin B1 hepatotoxicity in rats by a mechanism that depends on tumor necrosis factor alpha

21 January 2018

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Tumor necrosis factor alpha is a proximal mediator of synergistic hepatotoxicity from trovafloxacin/lipopolysaccharide coexposure

21 January 2018

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Circuitry of nuclear factor kappaB signaling

21 January 2018

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Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas.

21 January 2018

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Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

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Mechanisms of crosstalk between TNF-induced NF-kappaB and JNK activation in hepatocytes.

21 January 2018

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Mechanisms of liver disease: cross-talk between the NF-kappaB and JNK pathways

21 January 2018

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Suppression of chemically induced apoptosis but not necrosis of renal proximal tubular epithelial (LLC-PK1) cells by focal adhesion kinase (FAK). Role of FAK in maintaining focal adhesion organization after acute renal cell injury

21 January 2018

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Heat shock protein 27 is the major differentially phosphorylated protein involved in renal epithelial cellular stress response and controls focal adhesion organization and apoptosis

21 January 2018

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Bax-mediated mitochondrial outer membrane permeabilization (MOMP), distinct from the mitochondrial permeability transition, is a key mechanism in diclofenac-induced hepatocyte injury: Multiple protective roles of cyclosporin A.

21 January 2018

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Protection from diclofenac-induced small intestinal injury by the JNK inhibitor SP600125 in a mouse model of NSAID-associated enteropathy

21 January 2018

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The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

21 January 2018

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Antiapoptotic effect of c-Jun N-terminal Kinase-1 through Mcl-1 stabilization in TNF-induced hepatocyte apoptosis

21 January 2018

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Tumor necrosis factor-induced toxic liver injury results from JNK2-dependent activation of caspase-8 and the mitochondrial death pathway

21 January 2018

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Critical role of free cytosolic calcium, but not uncoupling, in mitochondrial permeability transition and cell death induced by diclofenac oxidative metabolites in immortalized human hepatocytes

21 January 2018

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Life in the balance: how BH3-only proteins induce apoptosis.

21 January 2018

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Mechanisms of cytochrome c release from mitochondria

21 January 2018

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Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS.

21 January 2018

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Enhanced death ligand-induced apoptosis in cutaneous SCC cells by treatment with diclofenac/hyaluronic acid correlates with downregulation of c-FLIP.

21 January 2018

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NF-kappaB at the crossroads of life and death

21 January 2018

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Understanding the role of reactive metabolites in drug-induced hepatotoxicity: state of the science

21 January 2018

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7 January 2021

Drug-induced liver injury

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7 January 2021

Signal transduction pathways involved in drug-induced liver injury

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7 January 2021

Modest inflammation enhances diclofenac hepatotoxicity in rats: role of neutrophils and bacterial translocation

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7 January 2021

High-throughput live cell imaging of apoptosis

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7 January 2021

A JNK-Dependent Pathway Is Required for TNFα-Induced Apoptosis

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7 January 2021

The pharmacokinetics of diclofenac sodium following intravenous and oral administration

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7 January 2021

Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans.

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7 January 2021

Identifiers

DOI

10.1002/HEP.24314

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29 July 2017

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