(Q33864231)

29 July 2017

title

Expression level, cellular compartment and metabolic network position all influence the average selective constraint on mammalian enzymes (English)

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29 July 2017

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29 July 2017

2

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29 July 2017

publication date

6 April 2011

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29 July 2017

published in

BMC Evolutionary Biology

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29 July 2017

volume

11

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29 July 2017

page(s)

89

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Evolutionary constraints permeate large metabolic networks

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Co-evolutionary networks of genes and cellular processes across fungal species

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Evolutionary rates and centrality in the yeast gene regulatory network

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Patterns of evolutionary constraints on genes in humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Evolutionary constraint and adaptation in the metabolic network of Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Functional protein divergence in the evolution of Homo sapiens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

The other side of the nearly neutral theory, evidence of slightly advantageous back-mutations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Nuclear organization of the genome and the potential for gene regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

PAML 4: phylogenetic analysis by maximum likelihood

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

A network perspective on the topological importance of enzymes and their phylogenetic conservation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Global reconstruction of the human metabolic network based on genomic and bibliomic data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Pegasoferae, an unexpected mammalian clade revealed by tracking ancient retroposon insertions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Modularity and community structure in networks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Influence of metabolic network structure and function on enzyme evolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Orthologs, paralogs, and evolutionary genomics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Why highly expressed proteins evolve slowly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Selectionism and neutralism in molecular evolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Finding community structure in very large networks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Mammalian phylogenomics comes of age

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Accuracy and power of statistical methods for detecting adaptive evolution in protein coding sequences and for identifying positively selected sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Characterization of evolutionary rates and constraints in three Mammalian genomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

MUSCLE: multiple sequence alignment with high accuracy and high throughput

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Finding and evaluating community structure in networks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

The origins of genome complexity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Apparent dependence of protein evolutionary rate on number of interactions is linked to biases in protein-protein interactions data sets

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

No simple dependence between protein evolution rate and the number of protein-protein interactions: only the most prolific interactors tend to evolve slowly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

The Bioperl toolkit: Perl modules for the life sciences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

GenomeHistory: a software tool and its application to fully sequenced genomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Essential genes are more evolutionarily conserved than are nonessential genes in bacteria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Evolutionary rate in the protein interaction network

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Testing the neutral theory of molecular evolution with genomic data from Drosophila.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Selection in the evolution of gene duplications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

HugeIndex: a database with visualization tools for high-density oligonucleotide array data from normal human tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Codon-substitution models for heterogeneous selection pressure at amino acid sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Maximum-likelihood estimation of phylogeny from DNA sequences when substitution rates differ over sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Evolutionary Rate at the Molecular Level

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Construction of phylogenetic trees

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

The rate of molecular evolution considered from the standpoint of population genetics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

A selection model of molecular evolution incorporating the effective population size

5 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2148-11-89

Genome-wide evidence for efficient positive and purifying selection in Capsella grandiflora, a plant species with a large effective population size

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2148-11-89

A single determinant dominates the rate of yeast protein evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2148-11-89

Do essential genes evolve slowly?

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2148-11-89

Protein dispensability and rate of evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2148-11-89

Molecular evolution in large genetic networks: does connectivity equal constraint?

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2148-11-89

A Set of Measures of Centrality Based on Betweenness

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2148-11-89

A faster algorithm for betweenness centrality*

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2148-11-89

Currency and commodity metabolites: their identification and relation to the modularity of metabolic networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2148-11-89

Impact of extracellularity on the evolutionary rate of mammalian proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2148-11-89

Centrality in social networks conceptual clarification

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2148-11-89

Genomic function (communication arising): Rate of evolution and gene dispensability

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2148-11-89

Essential Genes Are More Evolutionarily Conserved Than Are Nonessential Genes in Bacteria

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082228

Neutral evolution on mammalian protein surfaces

29 October 2018

1 reference

12 December 2020

Conservation and coevolution in the scale-free human gene coexpression network

1 reference

12 December 2020

Protein Evolution Is Faster Outside the Cell

1 reference

12 December 2020

Determinants of substitution rates in mammalian genes: expression pattern affects selection intensity but not mutation rate

1 reference

12 December 2020

Energy constraints on the evolution of gene expression

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2148-11-89

1 reference

Dimensions Publication ID

29 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2148-11-89

9 September 2019

1 reference

29 July 2017

1 reference