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Modeling human neurodegenerative diseases in Drosophila: on a wing and a prayer.
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scholarly article
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Europe PubMed Central
PubMed ID
10729831
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10729831%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
review article
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Europe PubMed Central
title
Modeling human neurodegenerative diseases in Drosophila: on a wing and a prayer
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10729831
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10729831%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
main subject
Drosophila
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neurodegeneration
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author
Nancy M. Bonini
series ordinal
2
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Europe PubMed Central
PubMed ID
10729831
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10729831%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
author name string
M E Fortini
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1
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Europe PubMed Central
PubMed ID
10729831
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10729831%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
publication date
1 April 2000
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Europe PubMed Central
PubMed ID
10729831
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10729831%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
published in
Trends in Genetics
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Europe PubMed Central
PubMed ID
10729831
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10729831%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
volume
16
1 reference
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Europe PubMed Central
PubMed ID
10729831
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10729831%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
page(s)
161-167
1 reference
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Europe PubMed Central
PubMed ID
10729831
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10729831%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
issue
4
1 reference
stated in
Europe PubMed Central
PubMed ID
10729831
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10729831%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
cites work
Spongecake and eggroll: two hereditary diseases in Drosophila resemble patterns of human brain degeneration
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Drosophila drop-dead mutations accelerate the time course of age-related markers
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Neural disease: Drosophila degenerates for a good cause.
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A genetic analysis of visual system development in Drosophilia melanogaster
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Cell degeneration in the developing optic lobes of the sine oculis and small-optic-lobes mutants of Drosophila melanogaster.
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The influence of retinal innervation on neurogenesis in the first optic ganglion of Drosophila.
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Retinal degeneration caused by dominant rhodopsin mutations in Drosophila.
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Analysis of mutants in chaoptin, a photoreceptor cell-specific glycoprotein in Drosophila, reveals its role in cellular morphogenesis
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Rab6 regulation of rhodopsin transport in Drosophila.
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Defective intracellular transport is the molecular basis of rhodopsin-dependent dominant retinal degeneration
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The Drosophila ninaC locus encodes two photoreceptor cell specific proteins with domains homologous to protein kinases and the myosin heavy chain head
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Arrestin function in inactivation of G protein-coupled receptor rhodopsin in vivo.
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Localization of Drosophila retinal degeneration B, a membrane-associated phosphatidylinositol transfer protein
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Rhodopsin activation causes retinal degeneration in Drosophila rdgC mutant.
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Drosophila retinal degeneration C (rdgC) encodes a novel serine/threonine protein phosphatase.
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Calcium channel blockers inhibit retinal degeneration in the retinal-degeneration-B mutant of Drosophila
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7 January 2021
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Blocking apoptosis prevents blindness in Drosophila retinal degeneration mutants.
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Wolbachia, normally a symbiont of Drosophila, can be virulent, causing degeneration and early death
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7 January 2021
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The swiss cheese mutant causes glial hyperwrapping and brain degeneration in Drosophila.
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Defective glia induce neuronal apoptosis in the repo visual system of Drosophila.
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Disruption of the CNTF gene results in motor neuron degeneration.
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Preventing neurodegeneration in the Drosophila mutant bubblegum
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Genetic neurodegenerative diseases: the human illness and transgenic models
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Protein fate in neurodegenerative proteinopathies: polyglutamine diseases join the (mis)fold
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Glutamine repeats and neurodegenerative diseases: molecular aspects
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Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.
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Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila.
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Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.
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Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.
1 reference
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7 January 2021
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Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract
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Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease
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The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease
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Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene
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7 January 2021
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The Drosophila beta-amyloid precursor protein homolog promotes synapse differentiation at the neuromuscular junction.
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Presenilin is required for activity and nuclear access of Notch in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
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7 January 2021
based on heuristic
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A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
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7 January 2021
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Apoptotic activities of wild-type and Alzheimer's disease-related mutant presenilins in Drosophila melanogaster
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
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7 January 2021
based on heuristic
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Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Is apoptosis key in Alzheimer's disease?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
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7 January 2021
based on heuristic
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Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
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7 January 2021
based on heuristic
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Assessment of normal and mutant human presenilin function in Caenorhabditis elegans
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Lessons from hereditary colorectal cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
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7 January 2021
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Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
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7 January 2021
based on heuristic
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1 reference
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https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
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7 January 2021
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Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons.
1 reference
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7 January 2021
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Activated Drosophila Ras1 is selectively suppressed by isoprenyl transferase inhibitors
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
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7 January 2021
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Lights out: deactivation of the phototransduction cascade
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0168-9525%2899%2901939-3
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7 January 2021
based on heuristic
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Identifiers
DOI
10.1016/S0168-9525(99)01939-3
1 reference
stated in
Europe PubMed Central
PubMed ID
10729831
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10729831%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
PubMed ID
10729831
1 reference
stated in
Europe PubMed Central
PubMed ID
10729831
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10729831%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
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