(Q33892460)

29 July 2017

An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancer (English)

1 reference

29 July 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Michael A Welsh

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Lalage M Wakefield

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Misako Sato

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Binwu Tang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Howard H Yang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Yu-an Yang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Mengge Shan

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Jia Weng

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Kathleen C Flanders

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Yoshiko Nagano

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Aleksandra M Michalowski

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Robert J Clifford

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Maxwell P Lee

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

publication date

2 June 2014

1 reference

29 July 2017

Breast Cancer Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

R57

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1186/bcr3668

6 June 2020

exact match

0 references

cites work

Targeting the TGFβ signalling pathway in disease

1 reference

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TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer

5 July 2018

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Specific interactions between Smad proteins and AP-1 components determine TGFβ-induced breast cancer cell invasion.

5 July 2018

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H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells

5 July 2018

1 reference

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The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites

5 July 2018

1 reference

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Biological responses to TGF-β in the mammary epithelium show a complex dependency on Smad3 gene dosage with important implications for tumor progression

5 July 2018

1 reference

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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

5 July 2018

1 reference

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Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity.

5 July 2018

1 reference

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TGF-β receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanisms

5 July 2018

1 reference

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EphA receptor signaling--complexity and emerging themes

5 July 2018

1 reference

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Master transcription factors determine cell-type-specific responses to TGF-β signaling

5 July 2018

1 reference

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Most random gene expression signatures are significantly associated with breast cancer outcome

5 July 2018

1 reference

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ChIP-seq defined genome-wide map of TGFβ/SMAD4 targets: implications with clinical outcome of ovarian cancer

5 July 2018

1 reference

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Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast

5 July 2018

1 reference

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Cell type-specific target selection by combinatorial binding of Smad2/3 proteins and hepatocyte nuclear factor 4alpha in HepG2 cells

5 July 2018

1 reference

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High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells

5 July 2018

1 reference

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GOBO: gene expression-based outcome for breast cancer online

5 July 2018

1 reference

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A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland

5 July 2018

1 reference

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TGF-beta biology in mammary development and breast cancer

5 July 2018

1 reference

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Breast cancer prognostic classification in the molecular era: the role of histological grade

5 July 2018

1 reference

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Murine protein serine/threonine kinase 38 stimulates TGF-beta signaling in a kinase-dependent manner via direct phosphorylation of Smad proteins

5 July 2018

1 reference

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TGFbeta signalling: a complex web in cancer progression

5 July 2018

1 reference

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Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways

5 July 2018

1 reference

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A pathway-based classification of human breast cancer.

5 July 2018

1 reference

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Eph receptors and ephrins in cancer: bidirectional signalling and beyond

5 July 2018

1 reference

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Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines

5 July 2018

1 reference

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Advanced glycation end-products induce tubular CTGF via TGF-beta-independent Smad3 signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells.

5 July 2018

1 reference

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PIK3CA in breast carcinoma: a mutational analysis of sporadic and hereditary cases

5 July 2018

1 reference

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Gain or loss of TGFbeta signaling in mammary carcinoma cells can promote metastasis

5 July 2018

1 reference

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The Integrated Genome Browser: free software for distribution and exploration of genome-scale datasets

5 July 2018

1 reference

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An integration of complementary strategies for gene-expression analysis to reveal novel therapeutic opportunities for breast cancer.

5 July 2018

1 reference

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Transforming growth factor-beta signaling and tumor angiogenesis

5 July 2018

1 reference

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Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer

5 July 2018

1 reference

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Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.

5 July 2018

1 reference

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Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling.

5 July 2018

1 reference

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5 July 2018

1 reference

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Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Cell cycle correlated genes dictate the prognostic power of breast cancer gene lists

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment

5 July 2018

1 reference

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''R"--project for statistical computing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

The genomic landscapes of human breast and colorectal cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Transforming growth factor-beta can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Allele-specific chromatin immunoprecipitation studies show genetic influence on chromatin state in human genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Molecular definition of breast tumor heterogeneity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Transforming growth factor-beta during carcinogenesis: the shift from epithelial to mesenchymal signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Proliferation of estrogen receptor-alpha-positive mammary epithelial cells is restrained by transforming growth factor-beta1 in adult mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Decreased tumorigenic potential of EphA2-overexpressing breast cancer cells following treatment with adenoviral vectors that express EphrinA1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Cooperation of the ErbB2 receptor and transforming growth factor beta in induction of migration and invasion in mammary epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

A gene-expression signature as a predictor of survival in breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Defects in TGF-beta signaling overcome senescence of mouse keratinocytes expressing v-Ha-ras

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Transcriptional activation of functional endogenous estrogen receptor gene expression in MCF10AT cells: a model for early breast cancer.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Direct action of estrogen on sequence of progression of human preneoplastic breast disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Heterogeneous activation of the TGFbeta pathway in glioblastomas identified by gene expression-based classification using TGFbeta-responsive genes

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FBCR3668

Malignant MCF10CA1 cell lines derived from premalignant human breast epithelial MCF10AT cells.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FBCR3668

Tamoxifen suppresses histologic progression to atypia and DCIS in MCFIOAT xenografts, a model of early human breast cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FBCR3668

EphA2 overexpression causes tumorigenesis of mammary epithelial cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Breast stroma plays a dominant regulatory role in breast epithelial growth and differentiation: implications for tumor development and progression.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095608

Transforming growth factor beta 1 suppresses genomic instability independent of a G1 arrest, p53, and Rb

29 October 2018

1 reference

12 December 2020

Progression of premalignant MCF10AT generates heterogeneous malignant variants with characteristic histologic types and immunohistochemical markers.

1 reference

12 December 2020

Ephrin-A1 facilitates mammary tumor metastasis through an angiogenesis-dependent mechanism mediated by EphA receptor and vascular endothelial growth factor in mice

1 reference

12 December 2020

Biological Cross-talk between WNK1 and the Transforming Growth Factor β-Smad Signaling Pathway

1 reference

12 December 2020

Transforming growth factor-beta and breast cancer risk in women with mammary epithelial hyperplasia

1 reference

12 December 2020

Molecular profiling: moving away from tumor philately

1 reference

12 December 2020

Identifiers

DOI

10.1186/BCR3668

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24890385%20AND%20SRC:MED&resulttype=core&format=json