(Q33900561)

English

Altered axonal architecture by removal of the heavily phosphorylated neurofilament tail domains strongly slows superoxide dismutase 1 mutant-mediated ALS.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Altered axonal architecture by removal of the heavily phosphorylated neurofilament tail domains strongly slows superoxide dismutase 1 mutant-mediated ALS. (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

phosphorylation

0 references

amyotrophic lateral sclerosis

1 reference

based on heuristic

inferred from title

Don W. Cleveland

4

object named as

Don W Cleveland

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Christian S Lobsiger

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Michael L Garcia

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Christopher M Ward

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

0 references

publication date

7 July 2005

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

102

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

29

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

10351-10356

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Elevation of the Hsp70 chaperone does not effect toxicity in mouse models of familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Unraveling the mechanisms involved in motor neuron degeneration in ALS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

NF-M is an essential target for the myelin-directed "outside-in" signaling cascade that mediates radial axonal growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Does neurofilament phosphorylation regulate axonal transport?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Disruption of the NF-H gene increases axonal microtubule content and velocity of neurofilament transport: relief of axonopathy resulting from the toxin beta,beta'-iminodipropionitrile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments does not require the neurofilament heavy subunit (NF-H) or its phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Neurofilament subunit NF-H modulates axonal diameter by selectively slowing neurofilament transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Neuronal intermediate filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Fine structural observations of neurofilamentous changes in amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

In vivo microtubules are copolymers of available beta-tubulin isotypes: localization of each of six vertebrate beta-tubulin isotypes using polyclonal antibodies elicited by synthetic peptide antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

Cytopathology of amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177385

5 July 2018

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503862102

21 January 2018

Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503862102

21 January 2018

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503862102

21 January 2018

Mutant superoxide dismutase 1 causes motor neuron degeneration independent of cyclin-dependent kinase 5 activation by p35 or p25.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503862102

21 January 2018

Peripherin is not a contributing factor to motor neuron disease in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503862102

21 January 2018

The neuroprotective factor Wlds does not attenuate mutant SOD1-mediated motor neuron disease

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503862102

21 January 2018

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503862102

21 January 2018

Quantitative immunocytochemical analysis of the spinal cord in G86R superoxide dismutase transgenic mice: neurochemical correlates of selective vulnerability

1 reference

https://pubmed.ncbi.nlm.nih.gov/16002469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of neurofilament subunit NF-L and NF-H extends survival of a mouse model for amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16002469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

1 reference

https://pubmed.ncbi.nlm.nih.gov/16002469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphometric Comparison of the Vulnerability of Peripheral Motor and Sensory Neurons in Amyotrophic Lateral Sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16002469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fine structural study of neurofibrillary changes in a family with amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16002469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial adult motor neuron disease: amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16002469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16002469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0503862102

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

2005PNAS..10210351L

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

0 references

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