(Q33900572)

29 July 2017

title

cAMP-response element-binding protein and heat-shock protein 70 additively suppress polyglutamine-mediated toxicity in Drosophila (English)

1 reference

29 July 2017

0 references

Kanae Iijima-Ando

1

1 reference

29 July 2017

Priscilla Wu

2

1 reference

29 July 2017

Eric A Drier

3

1 reference

29 July 2017

Koichi Iijima

4

1 reference

29 July 2017

Jerry C P Yin

5

1 reference

29 July 2017

language of work or name

English

0 references

publication date

11 July 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

1 reference

29 July 2017

volume

102

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29 July 2017

issue

29

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29 July 2017

page(s)

10261-10266

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Identification of combinatorial drug regimens for treatment of Huntington's disease using Drosophila.

29 July 2017

cites work

1 reference

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5 July 2018

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Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation

5 July 2018

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5 July 2018

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Aberrant histone acetylation, altered transcription, and retinal degeneration in a Drosophila model of polyglutamine disease are rescued by CREB-binding protein

5 July 2018

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Overexpression of heat shock protein 70 in R6/2 Huntington's disease mice has only modest effects on disease progression

5 July 2018

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Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

5 July 2018

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Cell death triggered by polyglutamine-expanded huntingtin in a neuronal cell line is associated with degradation of CREB-binding protein

5 July 2018

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5 July 2018

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Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease

5 July 2018

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Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects

5 July 2018

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Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

5 July 2018

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Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB

5 July 2018

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Disruption of CREB function in brain leads to neurodegeneration

5 July 2018

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Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

5 July 2018

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Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease

5 July 2018

1 reference

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Transcriptional regulation by the phosphorylation-dependent factor CREB

5 July 2018

1 reference

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Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

5 July 2018

1 reference

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CREB-binding protein sequestration by expanded polyglutamine

5 July 2018

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Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

5 July 2018

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5 July 2018

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Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

5 July 2018

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A Drosophila model of Parkinson's disease

5 July 2018

1 reference

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Genetic suppression of polyglutamine toxicity in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1177387

Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins

5 July 2018

1 reference

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Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila

5 July 2018

1 reference

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Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone

5 July 2018

1 reference

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Transcriptional activation modulated by homopolymeric glutamine and proline stretches

5 July 2018

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Transformation of mammalian cells by constitutively active MAP kinase kinase

5 July 2018

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Protein kinase A and hedgehog signaling in Drosophila limb development

5 July 2018

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CREB as a memory modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in Drosophila

5 July 2018

1 reference

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Decreased cAMP response element-mediated transcription: an early event in exon 1 and full-length cell models of Huntington's disease that contributes to polyglutamine pathogenesis

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

CRE-mediated transcription is increased in Huntington's disease transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Identification of genes that modify ataxin-1-induced neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Pharmacological prevention of Parkinson disease in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

The Drosophila dCREB2 gene affects the circadian clock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Disease progression despite early loss of polyglutamine protein expression in SCA7 mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Hydrogen peroxide-mediated phosphorylation of ERK1/2, Akt/PKB and JNK in cortical neurones: dependence on Ca(2+) and PI3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Mitogen and stress response kinase-1 (MSK1) mediates excitotoxic induced death of hippocampal neurones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Neurodegeneration. A glutamine-rich trail leads to transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

A non-circadian role for cAMP signaling and CREB activity in Drosophila rest homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Persistent CREB Phosphorylation with Protection of Hippocampal CA1 Pyramidal Neurons Following Temporary Occlusion of the Middle Cerebral Artery in the Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503937102

Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein

21 January 2018

1 reference

12 December 2020

Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease

1 reference

12 December 2020

Differential activation of MAPK/ERK and p38/SAPK in neurones and glia following focal cerebral ischaemia in the rat

1 reference

12 December 2020

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0503937102

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference