(Q40502075)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15494410%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Hsp70 and Hsp40 chaperones do not modulate retinal phenotype in SCA7 mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15494410%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

0 references

5

1 reference

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4 January 2020

Dom Helmlinger

1

1 reference

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4 January 2020

Jean-Louis Mandel

3

1 reference

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4 January 2020

Yvon Trottier

4

1 reference

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4 January 2020

author name string

Jacques Bonnet

2

1 reference

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4 January 2020

language of work or name

English

0 references

publication date

19 October 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15494410%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

4 January 2020

published in

1 reference

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4 January 2020

volume

279

1 reference

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4 January 2020

issue

53

1 reference

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4 January 2020

page(s)

55969-55977

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15494410%20AND%20SRC:MED&resulttype=core&format=json

Spinocerebellar ataxia type 7 associated with pigmentary retinal dystrophy

4 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Glutamine repeats and neurodegeneration

21 January 2018

1 reference

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Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Huntingtin aggregation and toxicity in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

The role of chaperones in polyglutamine disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

SCA7 knockin mice model human SCA7 and reveal gradual accumulation of mutant ataxin-7 in neurons and abnormalities in short-term plasticity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Identification and localization of ataxin-7 in brain and retina of a patient with cerebellar ataxia type II using anti-peptide antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

21 January 2018

1 reference

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Two populations of neuronal intranuclear inclusions in SCA7 differ in size and promyelocytic leukaemia protein content

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Progressive retinal degeneration and dysfunction in R6 Huntington's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Genetic suppression of polyglutamine toxicity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Identification of genes that modify ataxin-1-induced neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Molecular chaperones in the cytosol: from nascent chain to folded protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Overexpression of heat shock protein 70 in R6/2 Huntington's disease mice has only modest effects on disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Disease progression despite early loss of polyglutamine protein expression in SCA7 mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

The carboxy-terminal domain of Hsc70 provides binding sites for a distinct set of chaperone cofactors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Hsp105alpha suppresses the aggregation of truncated androgen receptor with expanded CAG repeats and cell toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Characterization of a brain-enriched chaperone, MRJ, that inhibits Huntingtin aggregation and toxicity independently

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Bacterial and yeast chaperones reduce both aggregate formation and cell death in mammalian cell models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Intranuclear ataxin1 inclusions contain both fast- and slow-exchanging components

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Pathogenesis of polyglutamine disorders: aggregation revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

RNA-mediated neurodegeneration caused by the fragile X premutation rCGG repeats in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Heat-shock proteins as regulators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Protein aggregation and the ubiquitin proteasome pathway: gaining the UPPer hand on neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

Chaperone suppression of cellular toxicity of huntingtin is independent of polyglutamine aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

SCA7 mouse models show selective stabilization of mutant ataxin-7 and similar cellular responses in different neuronal cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409062200

21 January 2018

Identifiers

DOI

10.1074/JBC.M409062200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15494410%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference