(Q33902262)

29 July 2017

title

TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus (English)

1 reference

29 July 2017

0 references

1 reference

1 reference

Kevin M Nickerson

1

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29 July 2017

Sean R Christensen

2

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29 July 2017

Jonathan Shupe

3

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29 July 2017

Michael Kashgarian

4

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29 July 2017

Daniel Kim

5

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29 July 2017

Keith Elkon

6

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29 July 2017

Mark J Shlomchik

7

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29 July 2017

language of work or name

English

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publication date

20 January 2010

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29 July 2017

published in

Journal of Immunology

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29 July 2017

volume

184

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29 July 2017

issue

4

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29 July 2017

page(s)

1840-1848

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describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4098568/fullTextXML

inferred from PubMed Central ID database lookup

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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B cells are required for lupus nephritis in the polygenic, Fas-intact MRL model of systemic autoimmunity.

28 July 2018

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28 July 2018

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Host modifier genes affect mouse autoimmunity induced by the lpr gene

28 July 2018

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V region gene analysis of anti-Sm hybridomas from MRL/Mp-lpr/lpr mice.

28 July 2018

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A rheumatoid factor transgenic mouse model of autoantibody regulation

28 July 2018

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Novel packages of viral and self-antigens are generated during apoptosis

28 July 2018

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Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

28 July 2018

1 reference

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Frequency and epitope recognition of anti-ribosome P antibodies from humans with systemic lupus erythematosus and MRL/lpr mice are similar

28 July 2018

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Analysis of antibodies to RNA in patients with systemic lupus erythematosus and other autoimmune rheumatic diseases

28 July 2018

1 reference

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Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Etiology and pathogenesis of a spontaneous lupus-like syndrome in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

The innate immune response to DNA.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Trex1 prevents cell-intrinsic initiation of autoimmunity

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Development of TLR inhibitors for the treatment of autoimmune diseases

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Turning NF-kappaB and IRFs on and off in DC.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

The functional effects of physical interactions among Toll-like receptors 7, 8, and 9.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Nucleosomes are exposed at the cell surface in apoptosis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Plasma cells for a lifetime?

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Specificities and genetic characteristics of nucleosome-reactive antibodies from autoimmune mice.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4098568

Protection against autoimmune nephritis in MyD88-deficient MRL/lpr mice

29 October 2018

1 reference

12 December 2020

Murine dendritic cell type I IFN production induced by human IgG-RNA immune complexes is IFN regulatory factor (IRF)5 and IRF7 dependent and is required for IL-6 production

1 reference

12 December 2020

Inhibition of Toll-like receptor-7 (TLR-7) or TLR-7 plus TLR-9 attenuates glomerulonephritis and lung injury in experimental lupus

1 reference

12 December 2020

Treatment of lupus-prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms

1 reference

12 December 2020

Genetic dissection of vasculitis in MRL/lpr lupus mice: a novel susceptibility locus involving the CD72c allele

1 reference

12 December 2020

Blebs and apoptotic bodies are B cell autoantigens

1 reference

12 December 2020

The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodies

1 reference

12 December 2020

Dermatopathological studies on skin lesions of MRL mice

1 reference

12 December 2020

Interaction of mutant lpr gene with background strain influences renal disease

1 reference

12 December 2020

Oligoclonality of rheumatoid factors arising spontaneously in lpr/lpr mice

1 reference

12 December 2020

Phenotypes of immunocompetent cells and Ia antigen expression in oral mucosa and skin of autoimmune mouse strains

1 reference

12 December 2020

Murine lupus in the absence of alpha beta T cells

1 reference

12 December 2020

Propagation and regulation of systemic autoimmunity by gammadelta T cells

1 reference

12 December 2020

Pathogenesis of autoimmunity in alphabeta T cell-deficient lupus-prone mice

1 reference

12 December 2020

Perforin protects against autoimmunity in lupus-prone mice

1 reference

12 December 2020

Role of TLR9 in anti-nucleosome and anti-DNA antibody production in lpr mutation-induced murine lupus

1 reference

12 December 2020

Toll-like receptor 9-independent aggravation of glomerulonephritis in a novel model of SLE

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.0902592

1 reference

29 July 2017

1 reference

29 July 2017

1 reference