(Q33905239)

29 July 2017

title

Are ancient proteins responsible for the age-related decline in health and fitness? (English)

1 reference

29 July 2017

author name string

Roger John Willis Truscott

series ordinal

1

1 reference

29 July 2017

language of work or name

English

0 references

publication date

1 February 2010

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29 July 2017

published in

Rejuvenation Research

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29 July 2017

volume

13

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29 July 2017

issue

1

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29 July 2017

page(s)

83-89

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Mechanism of lysine oxidation in human lens crystallins during aging and in diabetes.

29 July 2017

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Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat.

5 July 2018

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Protein aging: truncation of aquaporin 0 in human lens regions is a continuous age-dependent process

5 July 2018

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Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection

5 July 2018

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Presbyopia. Emerging from a blur towards an understanding of the molecular basis for this most common eye condition

5 July 2018

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Dynamics of fat cell turnover in humans

5 July 2018

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Restoration of accommodation: surgical options for correction of presbyopia

5 July 2018

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Adult vitreous structure and postnatal changes

5 July 2018

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Molecular and cellular aspects of protein misfolding and disease

5 July 2018

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Radiocarbon dating of the human eye lens crystallines reveal proteins without carbon turnover throughout life

5 July 2018

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Rapid increase in human life expectancy: will it soon be limited by the aging of elastin?

5 July 2018

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Biological aging is no longer an unsolved problem

5 July 2018

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Vitamin C mediates chemical aging of lens crystallins by the Maillard reaction in a humanized mouse model

5 July 2018

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5 July 2018

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Neocortical neurogenesis in humans is restricted to development

5 July 2018

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Presbyopia: the first stage of nuclear cataract?

5 July 2018

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Retrospective birth dating of cells in humans

5 July 2018

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5 July 2018

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Methionine oxidation and aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Post-translational modifications of aquaporin 0 (AQP0) in the normal human lens: spatial and temporal occurrence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

REPLACEMENT RATES FOR HUMAN TISSUE FROM ATMOSPHERIC RADIOCARBON.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

BetaB2-crystallin undergoes extensive truncation during aging in human lenses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Racemization of aspartic acid in human proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid

5 July 2018

1 reference

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Crystal structure and assembly of a eukaryotic small heat shock protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Photo-oxidation of proteins and its role in cataractogenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Deamidation of human proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Cataract blindness--challenges for the 21st century

5 July 2018

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Age-dependent changes in the expression of matrix components in the mouse eye

5 July 2018

1 reference

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Major changes in human ocular UV protection with age.

5 July 2018

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Glutathione: a vital lens antioxidant

5 July 2018

1 reference

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Characterization of human lens major intrinsic protein structure

5 July 2018

1 reference

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Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice.

5 July 2018

1 reference

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Post-translational modifications of water-soluble human lens crystallins from young adults

5 July 2018

1 reference

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The redox couple between glutathione and ascorbic acid: a chemical and physiological perspective

5 July 2018

1 reference

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Mitochondrial decay in aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Further Investigations of the Transfer of Bomb 14C to Man

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Racemization of individual aspartate residues in human myelin basic protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Effect of long-term monitoring of glycosylated hemoglobin levels in insulin-dependent diabetes mellitus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Marked longevity of human lung parenchymal elastic fibers deduced from prevalence of D-aspartate and nuclear weapons-related radiocarbon

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Metal-catalyzed oxidation of proteins. Physiological consequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Modification of histidine residues in proteins by reaction with 4-hydroxynonenal

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Altered aspartate in Alzheimer neurofibrillary tangles.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Protein oxidation and aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Aspartic acid racemisation in the human lens during ageing and in cataract formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Oxidative changes in human lens proteins during senile nuclear cataract formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Collagen turnover in normal and degenerate human intervertebral discs as determined by the racemization of aspartic acid

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Advances in vertebrate aging research 2007.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Protein repair in the brain, proteomic analysis of endogenous substrates for protein L-isoaspartyl methyltransferase in mouse brain

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Triosidines: novel Maillard reaction products and cross-links from the reaction of triose sugars with lysine and arginine residues

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Racemization and isomerization of type I collagen C-telopeptides in human bone and soft tissues: assessment of tissue turnover

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Increased cleavage of the c-terminal serine from alpha-A crystallin present in the high molecular weight aggregate fraction from human and bovine lenses

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883525

Spatial and temporal mapping of the age-related changes in human lens crystallins

29 October 2018

1 reference

12 December 2020

Estimation of age from a tooth by means of racemization of an amino acid, especially aspartic acid--comparison of enamel and dentin

1 reference

12 December 2020

On the accumulation of d-aspartate in elastin and other proteins of the ageing aorta

1 reference

12 December 2020

Importance of vitreous liquefaction in age-related cataract

1 reference

12 December 2020

Glutathione inhibits the glycation and crosslinking of lens proteins by ascorbic acid

1 reference

12 December 2020

Identification of glutathionyl-3-hydroxykynurenine glucoside as a novel fluorophore associated with aging of the human lens

1 reference

12 December 2020

Chemical modification of proteins by methylglyoxal

1 reference

12 December 2020

Presbyopia and heat: changes associated with aging of the human lens suggest a functional role for the small heat shock protein, alpha-crystallin, in maintaining lens flexibility

1 reference

12 December 2020

The stiffness of human cataract lenses is a function of both age and the type of cataract

1 reference

12 December 2020

The non-oxidative degradation of ascorbic acid at physiological conditions

1 reference

12 December 2020

Comparison of d-aspartic acid contents in alpha A-crystallin from normal and age-matched cataractous human lenses

1 reference

12 December 2020

Age-dependent deamidation of alpha B-crystallin

1 reference

12 December 2020

Atomic bomb effect: variation of radiocarbon in plants, shells, and snails in the past 4 years

1 reference

12 December 2020

Massive increase in the stiffness of the human lens nucleus with age: the basis for presbyopia?

1 reference

12 December 2020

Post-translational modifications in the nuclear region of young, aged, and cataract human lenses

1 reference

12 December 2020

Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting

1 reference

12 December 2020

Glutamine deamidation destabilizes human gammaD-crystallin and lowers the kinetic barrier to unfolding

1 reference

12 December 2020

Identifiers

DOI

10.1089/REJ.2009.0938

1 reference

release_pud3t3iawrginio6bvxpozzrra

29 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pud3t3iawrginio6bvxpozzrra

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2883525

1 reference

29 July 2017

1 reference