(Q33911391)

30 July 2017

title

IGF1R signaling in Ewing sarcoma is shaped by clathrin-/caveolin-dependent endocytosis (English)

1 reference

30 July 2017

Giuseppe Floris

5

0 references

Enrique de Alava

object named as

Enrique de Alava

8

0 references

Maria Debiec-Rychter

6

object named as

Maria Debiec-Rychter

1 reference

30 July 2017

Pancras C.W. Hogendoorn

7

object named as

Pancras C W Hogendoorn

1 reference

30 July 2017

Ana Sofia Martins

1

1 reference

30 July 2017

José Luis Ordóñez

2

1 reference

30 July 2017

Ana Teresa Amaral

3

1 reference

30 July 2017

Frans Prins

4

1 reference

30 July 2017

language of work or name

English

0 references

publication date

17 May 2011

1 reference

30 July 2017

1 reference

30 July 2017

volume

6

1 reference

30 July 2017

issue

5

1 reference

30 July 2017

page(s)

e19846

1 reference

Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

17 May 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors

5 July 2018

1 reference

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Cross-talk between the ErbB/HER family and the type I insulin-like growth factor receptor signaling pathway in breast cancer

5 July 2018

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IGF-1 receptor inhibitors in clinical trials--early lessons

5 July 2018

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Insulin receptor expression by human prostate cancers

5 July 2018

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A pivotal role for heat shock protein 90 in Ewing sarcoma resistance to anti-insulin-like growth factor 1 receptor treatment: in vitro and in vivo study.

5 July 2018

1 reference

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Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis

5 July 2018

1 reference

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Knockdown of insulin-like growth factor 1 receptor enhances chemosensitivity to cisplatin in human lung adenocarcinoma A549 cells

5 July 2018

1 reference

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Silencing of the type 1 insulin-like growth factor receptor increases the sensitivity to apoptosis and inhibits invasion in human lung adenocarcinoma A549 cells.

5 July 2018

1 reference

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Clathrin-dependent mechanisms of G protein-coupled receptor endocytosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096649

Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096649

Insulin-like growth factor I receptor pathway inhibition by ADW742, alone or in combination with imatinib, doxorubicin, or vincristine, is a novel therapeutic approach in Ewing tumor.

5 July 2018

1 reference

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Degradation of insulin-like growth factor-I receptor occurs via ubiquitin-proteasome pathway in human lung cancer cells

5 July 2018

1 reference

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A role for caveolae in cell migration.

5 July 2018

1 reference

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Impact of IGF-I/IGF-IR circuit on the angiogenetic properties of Ewing's sarcoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096649

Platelet-derived growth factor receptor-mediated signal transduction from endosomes

5 July 2018

1 reference

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Caveolin regulation of endothelial function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096649

Endocytosis and signaling. an inseparable partnership

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096649

Cholesterol depletion disrupts caveolae and insulin receptor signaling for metabolic control via insulin receptor substrate-1, but not for mitogen-activated protein kinase control

5 July 2018

1 reference

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Regulation of signal transduction by endocytosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096649

Insulin-like growth factor-I receptor internalization regulates signaling via the Shc/mitogen-activated protein kinase pathway, but not the insulin receptor substrate-1 pathway

5 July 2018

1 reference

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Clathrin-mediated endocytosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of beta-arrestin1

5 July 2018

1 reference

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The insulin-like growth factor-I receptor is required for EWS/FLI-1 transformation of fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096649

Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096649

Involvement of Src-homology/collagen (SHC) proteins in signaling through the insulin receptor and the insulin-like-growth-factor-I-receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3096649

Insulin receptor internalization: molecular mechanisms and physiopathological implications

5 July 2018

1 reference

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Insulin receptor substrate 1 mediates insulin and insulin-like growth factor I-stimulated maturation of Xenopus oocytes

5 July 2018

1 reference

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Receptor-mediated endocytosis and lysosomal processing of insulin-like growth factor I by mitogenically responsive cells

5 July 2018

1 reference

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Insulin-like growth factor type-I receptor internalization and recycling mediate the sustained phosphorylation of Akt.

5 July 2018

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Increased expression of insulin-like growth factor I and/or its receptor in gastrinomas is associated with low curability, increased growth, and development of metastases.

21 January 2018

1 reference

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Regulation of insulin receptor substrate-1 expression levels by caveolin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019846

Essential role of caveolae in interleukin-6- and insulin-like growth factor I-triggered Akt-1-mediated survival of multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019846

NPXY motif in the insulin-like growth factor-I receptor is required for efficient ligand-mediated receptor internalization and biological signaling

21 January 2018

1 reference

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Targeting the type 1 insulin-like growth factor receptor as a treatment for cancer

29 October 2018

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12 December 2020

Targeted therapies in adult soft tissue sarcomas

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12 December 2020

IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3'-kinase

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12 December 2020

Growth advantage of human leiomyoma cells compared to normal smooth-muscle cells due to enhanced sensitivity toward insulin-like growth factor I

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0019846

Identifiers

DOI

1 reference

release_nkighbykmnhwdoftj4f437bqlq

30 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nkighbykmnhwdoftj4f437bqlq

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3096649

1 reference

30 July 2017

1 reference