(Q33911448)

30 July 2017

title

Selectivity of digitalis glycosides for isoforms of human Na,K-ATPase (English)

1 reference

30 July 2017

2

Yael Lifshitz

1 reference

30 July 2017

7

Steven J D Karlish

1 reference

30 July 2017

1

Adriana Katz

1 reference

30 July 2017

5

Rivka Goldshleger

1 reference

30 July 2017

Elizabeta Bab-Dinitz

3

1 reference

30 July 2017

Einat Kapri-Pardes

series ordinal

4

1 reference

30 July 2017

Daniel M Tal

series ordinal

6

1 reference

30 July 2017

language of work or name

English

0 references

publication date

13 April 2010

1 reference

Journal of Biological Chemistry

30 July 2017

published in

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30 July 2017

volume

285

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30 July 2017

issue

25

1 reference

30 July 2017

page(s)

19582-19592

1 reference

The physiological significance of the cardiotonic steroid/ouabain-binding site of the Na,K-ATPase

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Crystal structure of the sodium-potassium pump (Na+,K+-ATPase) with bound potassium and ouabain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Crystal structure of the sodium-potassium pump at 2.4 A resolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targets

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

The pump, the exchanger, and endogenous ouabain: signaling mechanisms that link salt retention to hypertension

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

The Na/K-ATPase/Src complex and cardiotonic steroid-activated protein kinase cascades

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Calcium cycling and signaling in cardiac myocytes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Diverse biological responses to different cardiotonic steroids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Physiological role of the alpha1- and alpha2-isoforms of the Na+-K+-ATPase and biological significance of their cardiac glycoside binding site

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

How does salt retention raise blood pressure?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Role of FXYD proteins in ion transport

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Digoxin and reduction in mortality and hospitalization in heart failure: a comprehensive post hoc analysis of the DIG trial

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Ouabain, a steroid hormone that signals with slow calcium oscillations.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Structure-activity relationships for the hypertensinogenic activity of ouabain: role of the sugar and lactone ring

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Transport and pharmacological properties of nine different human Na, K-ATPase isozymes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Na+ pump low and high ouabain affinity alpha subunit isoforms are differently distributed in cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Differentiation between isoforms of Na+/K+-transporting ATPase from human and guinea-pig cardiac muscle through use of digitalis derivatives as analytical probes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

The lead structure in cardiac glycosides is 5 beta, 14 beta-androstane-3 beta 14-diol

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Cardiac glycosides. 7. Sugar stereochemistry and cardiac glycoside activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Digitalis receptor sugar binding site characteristics: a model based upon studies of Na+, K(+)-ATPase preparations with differing digitalis sensitivities.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Immunologic identification of Na+,K(+)-ATPase isoforms in myocardium. Isoform change in deoxycorticosterone acetate-salt hypertension

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.119248

Differential distribution and regulation of mouse cardiac Na+/K+-ATPase alpha1 and alpha2 subunits in T-tubule and surface sarcolemmal membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.119248

Sodium pump alpha2 subunits control myogenic tone and blood pressure in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.119248

Interactions between cardiac glycosides and sodium/potassium-ATPase: three-dimensional structure-activity relationship models for ligand binding to the E2-Pi form of the enzyme versus activity inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.119248

Purification of Na+,K+-ATPase expressed in Pichia pastoris reveals an essential role of phospholipid-protein interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.119248

Stabilization of Na(+),K(+)-ATPase purified from Pichia pastoris membranes by specific interactions with lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.119248

Purification of the human alpha2 Isoform of Na,K-ATPase expressed in Pichia pastoris. Stabilization by lipids and FXYD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.119248

Expression of Na+,K+-ATPase in Pichia pastoris: analysis of wild type and D369N mutant proteins by Fe2+-catalyzed oxidative cleavage and molecular modeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.119248

Ouabain and substrate affinities of human Na(+)-K(+)-ATPase alpha(1)beta(1), alpha(2)beta(1), and alpha(3)beta(1) when expressed separately in yeast cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Region specific regulation of sodium pump isoform and Na,Ca-exchanger expression in the failing human heart--right atrium vs left ventricle

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Ouabain-induced hypertension in the rat: relationships among plasma and tissue ouabain and blood pressure.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Interaction of (Na+,K+)-ATPases and digitalis genins. A general model for inhibitory activity

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2885237

Consequences of mutations to the phosphorylation site of the alpha-subunit of Na, K-ATPase for ATP binding and E1-E2 conformational equilibrium

29 October 2018

1 reference

12 December 2020

Structue-activity relationships of cardiotonic steroids for the inhibition of sodium- and potassium-dependent adenosine triphosphatase. I. Dissociation rate constants of various enzyme-cardiac glycoside complexes formed in the presence of magnesium

1 reference

12 December 2020

Na+/K+-ATPase alpha subunits as new targets in anticancer therapy

1 reference

12 December 2020

Cardiac glycosides. 6. Gitoxigenin C16 acetates, formates, methoxycarbonates, and digitoxosides. Synthesis and Na+,K+-ATPase inhibitory activities

1 reference

12 December 2020

Functional analysis of Na+/K+-ATPase isoform distribution in rat ventricular myocytes

1 reference

12 December 2020

Na(+)/K(+)-ATPase as a signal transducer

1 reference

12 December 2020

The effect of digoxin on mortality and morbidity in patients with heart failure

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.119248

1 reference

30 July 2017

1 reference

30 July 2017

1 reference