(Q33917436)

English

Healing for destruction: tRNA intron degradation in yeast is a two-step cytoplasmic process catalyzed by tRNA ligase Rlg1 and 5'-to-3' exonuclease Xrn1.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Healing for destruction: tRNA intron degradation in yeast is a two-step cytoplasmic process catalyzed by tRNA ligase Rlg1 and 5'-to-3' exonuclease Xrn1. (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

Jingyan Wu

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Anita K Hopper

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

publication date

1 July 2014

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Genes & Development

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

28

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1556-1561

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration

1 reference

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28 July 2018

Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function

1 reference

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28 July 2018

A rapid and sensitive non-radioactive method applicable for genome-wide analysis of Saccharomyces cerevisiae genes involved in small RNA biology

1 reference

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28 July 2018

Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models

1 reference

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Dxo1 is a new type of eukaryotic enzyme with both decapping and 5′-3′ exoribonuclease activity

1 reference

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28 July 2018

Diversity and roles of (t)RNA ligases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

The yeast rapid tRNA decay pathway primarily monitors the structural integrity of the acceptor and T-stems of mature tRNA.

1 reference

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28 July 2018

Systematic exploration of essential yeast gene function with temperature-sensitive mutants

1 reference

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28 July 2018

tRNA biology charges to the front

1 reference

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28 July 2018

Distinct and overlapping roles for two Dicer-like proteins in the RNA interference pathways of the ancient eukaryote Trypanosoma brucei

1 reference

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28 July 2018

Rex1p deficiency leads to accumulation of precursor initiator tRNAMet and polyadenylation of substrate RNAs in Saccharomyces cerevisiae

1 reference

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28 July 2018

Human RNA 5'-kinase (hClp1) can function as a tRNA splicing enzyme in vivo

1 reference

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28 July 2018

Competition between the Rex1 exonuclease and the La protein affects both Trf4p-mediated RNA quality control and pre-tRNA maturation

1 reference

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28 July 2018

The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs

1 reference

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28 July 2018

Plant tRNA ligases are multifunctional enzymes that have diverged in sequence and substrate specificity from RNA ligases of other phylogenetic origins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Possibility of cytoplasmic pre-tRNA splicing: the yeast tRNA splicing endonuclease mainly localizes on the mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3'-->5' degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Two reactions of Haloferax volcanii RNA splicing enzymes: joining of exons and circularization of introns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Functional profiling of the Saccharomyces cerevisiae genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Rat1p and Xrn1p are functionally interchangeable exoribonucleases that are restricted to and required in the nucleus and cytoplasm, respectively

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

The yeast tRNA splicing endonuclease: a tetrameric enzyme with two active site subunits homologous to the archaeal tRNA endonucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

An NAD derivative produced during transfer RNA splicing: ADP-ribose 1"-2" cyclic phosphate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

The 5' end of yeast 5.8S rRNA is generated by exonucleases from an upstream cleavage site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Mechanism of action of a yeast RNA ligase in tRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Assembly of a tRNA splicing complex: evidence for concerted excision and joining steps in splicing in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Saccharomyces cerevisiae tRNA ligase. Purification of the protein and isolation of the structural gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Conserved mechanism of tRNA splicing in eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

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Deletion analysis of a multifunctional yeast tRNA ligase polypeptide. Identification of essential and dispensable functional domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Yeast tRNA ligase mutants are nonviable and accumulate tRNA splicing intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Effect of growth rate on the amounts of ribosomal and transfer ribonucleic acids in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Splicing of yeast tRNA precursors: structure of the reaction intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Promoter region for yeast 5S ribosomal RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

28 July 2018

Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

29 October 2018

Proofreading and aminoacylation of tRNAs before export from the nucleus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102763

29 October 2018

Purification and characterization of a Saccharomyces cerevisiae exoribonuclease which yields 5'-mononucleotides by a 5' leads to 3' mode of hydrolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25030695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Order and intracellular location of the events involved in the maturation of a spliced tRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/25030695

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1101/GAD.244673.114

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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