(Q33918023)

30 July 2017

title

Phenylbutyrate therapy for pyruvate dehydrogenase complex deficiency and lactic acidosis. (English)

1 reference

30 July 2017

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9

Massimo Zeviani

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30 July 2017

Rosa Ferriero

1

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30 July 2017

Giuseppe Manco

2

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30 July 2017

Eleonora Lamantea

3

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30 July 2017

Edoardo Nusco

4

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30 July 2017

Maria I Ferrante

5

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30 July 2017

Paolo Sordino

6

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30 July 2017

Peter W Stacpoole

7

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30 July 2017

Brendan Lee

8

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30 July 2017

Nicola Brunetti-Pierri

10

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30 July 2017

language of work or name

English

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publication date

1 March 2013

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Science Translational Medicine

30 July 2017

published in

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30 July 2017

volume

5

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30 July 2017

issue

175

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30 July 2017

page(s)

175ra31

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describes a project that uses

30 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4102924/fullTextXML

inferred from PubMed Central ID database lookup

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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N-tert-butyl-alpha-phenylnitrone improves recovery of brain energy state in rats following transient focal ischemia

5 July 2018

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5 July 2018

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5 July 2018

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Lactate homeostasis and lactic acidosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102924

Treatment of Lactic Acidosis with Dichloroacetate in Dogs

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102924

Alpha-keto acid dehydrogenase complexes. X. Regulation of the activity of the pyruvate dehydrogenase complex from beef kidney mitochondria by phosphorylation and dephosphorylation

5 July 2018

1 reference

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Hydrogen ions kill brain at concentrations reached in ischemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102924

Regulation of lactate metabolism in vivo.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102924

Molecular biology and biochemistry of pyruvate dehydrogenase complexes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102924

Dynamics of interstitial and intracellular pH in evolving brain infarct

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102924

Effects of hyperglycemia on the time course of changes in energy metabolism and pH during global cerebral ischemia and reperfusion in rats: correlation of 1H and 31P NMR spectroscopy with fatty acid and excitatory amino acid levels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102924

Hyperglycemic versus normoglycemic stroke: topography of brain metabolites, intracellular pH, and infarct size

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102924

Sensitivity to carbohydrate in a patient with familial intermittent lactic acidosis and pyruvate dehydrogenase deficiency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102924

Defective activation of the pyruvate dehydrogenase complex in subacute necrotizing encephalomyelopathy (leigh disease)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102924

Effect of major hepatectomy on glucose and lactate metabolism.

5 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004986

Lactic acidemia in the pathogenesis of mice carrying mitochondrial DNA with a deletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004986

Acute hyperglycemia adversely affects stroke outcome: a magnetic resonance imaging and spectroscopy study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004986

Sodium phenylbutyrate ameliorates focal cerebral ischemic/reperfusion injury associated with comorbid type 2 diabetes by reducing endoplasmic reticulum stress and DNA fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004986

Sodium 4-phenylbutyrate protects against cerebral ischemic injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004986

A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004986

Lipoyl domain-based mechanism for the integrated feedback control of the pyruvate dehydrogenase complex by enhancement of pyruvate dehydrogenase kinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3004986

Therapeutic potential of pyruvate therapy for mitochondrial diseases.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102924

A phase I dose escalation and bioavailability study of oral sodium phenylbutyrate in patients with refractory solid tumor malignancies.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102924

Genetic disorders of vision revealed by a behavioral screen of 400 essential loci in zebrafish.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4102924

Biochemical analysis of phototransduction and visual cycle in zebrafish larvae

29 October 2018

1 reference

12 December 2020

Ketonic diet in the management of pyruvate dehydrogenase deficiency

1 reference

12 December 2020

Purification and properties of pyruvate dehydrogenase phosphatase from bovine heart and kidney

1 reference

12 December 2020

Dichloroacetate administration in the treatment of endotoxin shock

1 reference

12 December 2020

Isolated and combined deficiencies of the alpha-keto acid dehydrogenase complexes

1 reference

12 December 2020

Partial activation of the pyruvate dehydrogenase kinase by the lipoyl domain region of E2 and interchange of the kinase between lipoyl domain regions

1 reference

12 December 2020

Critical values for plasma glucose in aggravating ischaemic brain damage: correlation to extracellular pH

1 reference

12 December 2020

10.1126/SCITRANSLMED.3004986

Identifiers

DOI

1 reference

30 July 2017

1 reference

30 July 2017

1 reference