(Q33919627)

30 July 2017

title

Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome (English)

1 reference

30 July 2017

0 references

8

1 reference

30 July 2017

Jeremy Petravicz

5

0 references

Showming Kwok

3

object named as

Showming Kwok

1 reference

30 July 2017

9

Mriganka Sur

1 reference

30 July 2017

7

Nikolaos Mellios

1 reference

30 July 2017

Jorge Castro

1

1 reference

30 July 2017

Rodrigo I Garcia

2

1 reference

30 July 2017

Abhishek Banerjee

4

1 reference

30 July 2017

Jonathan Woodson

6

1 reference

30 July 2017

language of work or name

English

0 references

publication date

23 June 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

1 reference

30 July 2017

volume

111

1 reference

30 July 2017

issue

27

1 reference

30 July 2017

page(s)

9941-9946

1 reference

β2-Adrenergic receptor agonist ameliorates phenotypes and corrects microRNA-mediated IGF1 deficits in a mouse model of Rett syndrome

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Mutant astrocytes differentiated from Rett syndrome patients-specific iPSCs have adverse effects on wild-type neurons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Insulin-like growth factor-1 rescues synaptic and motor deficits in a mouse model of autism and developmental delay

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Mechanisms and therapeutic challenges in autism spectrum disorders: insights from Rett syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

The role of microglia in brain maintenance: implications for Rett syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Preclinical research in Rett syndrome: setting the foundation for translational success.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Female Mecp2(+/-) mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

A critical and cell-autonomous role for MeCP2 in synaptic scaling up

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

IGF1 as a Potential Treatment for Rett Syndrome: Safety Assessment in Six Rett Patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

MeCP2 is critical for maintaining mature neuronal networks and global brain anatomy during late stages of postnatal brain development and in the mature adult brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Postnatal inactivation reveals enhanced requirement for MeCP2 at distinct age windows

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Rett syndrome: genes, synapses, circuits, and therapeutics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

The many faces of insulin-like peptide signalling in the brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

The short-time structural plasticity of dendritic spines is altered in a model of Rett syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

A TrkB small molecule partial agonist rescues TrkB phosphorylation deficits and improves respiratory function in a mouse model of Rett syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

MeCP2 is critical within HoxB1-derived tissues of mice for normal lifespan

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Circulating IGF1 regulates hippocampal IGF1 levels and brain gene expression during adolescence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

The role of MeCP2 in the brain.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Experience-dependent retinogeniculate synapse remodeling is abnormal in MeCP2-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Postsynaptic BDNF-TrkB signaling in synapse maturation, plasticity, and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

MeCP2, a key contributor to neurological disease, activates and represses transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Glucose metabolism in vivo in four commonly used inbred mouse strains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

The story of Rett syndrome: from clinic to neurobiology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Brain-derived neurotrophic factor expression and respiratory function improve after ampakine treatment in a mouse model of Rett syndrome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Insulin-like growth factor 1 (IGF-1) mediates the effects of enriched environment (EE) on visual cortical development.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

BDNF induces transport of PSD-95 to dendrites through PI3K-AKT signaling after NMDA receptor activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Behavioral and anatomical abnormalities in Mecp2 mutant mice: a model for Rett syndrome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Reversal of neurological defects in a mouse model of Rett syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Signaling by insulin-like growth factor 1 in brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Eye opening induces a rapid dendritic localization of PSD-95 in central visual neurons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Mice with targeted gene disruptions or gene insertions for diabetes research: problems, pitfalls, and potential solutions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Viewpoint: are studies in genetically altered mice out of control?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Neuroprotection with noninvasive neurotrophin delivery to the brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311685111

Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311685111

Neuronal activity drives localized blood-brain-barrier transport of serum insulin-like growth factor-I into the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311685111

Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311685111

The role of different X-inactivation pattern on the variable clinical phenotype with Rett syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311685111

X chromosome inactivation in Rett Syndrome and its correlations with MECP2 mutations and phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311685111

Progressive motor and respiratory metabolism deficits in post-weaning Mecp2-null male mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311685111

PEGylation enhances the therapeutic potential for insulin-like growth factor I in central nervous system disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1311685111

Experience-dependent plasticity of binocular responses in the primary visual cortex of the mouse.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103342

Autonomic nervous system dysregulation: breathing and heart rate perturbation during wakefulness in young girls with Rett syndrome

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24958891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phosphoinositide-3-Kinase Activation Controls Synaptogenesis and Spinogenesis in Hippocampal Neurons

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24958891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Influence of mutation type and X chromosome inactivation on Rett syndrome phenotypes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24958891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1311685111

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference