(Q30445073)

English

Female Mecp2(+/-) mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies

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scholarly article

1 reference

Europe PubMed Central

14 August 2017

Female Mecp2(+/-) mice display robust behavioral deficits on two different genetic backgrounds providing a framework for pre-clinical studies (English)

1 reference

Europe PubMed Central

14 August 2017

1

object named as

Rodney C Samaco

1 reference

Europe PubMed Central

14 August 2017

Christopher S. Ward

object named as

Christopher S Ward

3

0 references

Jeffrey L. Neul

object named as

Jeffrey L Neul

5

0 references

object named as

Huda Y Zoghbi

6

0 references

author name string

Christopher M McGraw

2

1 reference

Europe PubMed Central

14 August 2017

Yaling Sun

4

1 reference

Europe PubMed Central

14 August 2017

publication date

1 October 2012

1 reference

Europe PubMed Central

14 August 2017

Human Molecular Genetics

1 reference

Europe PubMed Central

14 August 2017

22

1 reference

Europe PubMed Central

14 August 2017

1

1 reference

Europe PubMed Central

14 August 2017

96-109

1 reference

Europe PubMed Central

14 August 2017

Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

MeCP2 and Rett syndrome: reversibility and potential avenues for therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

MeCP2 is critical within HoxB1-derived tissues of mice for normal lifespan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Adult neural function requires MeCP2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Complexities of Rett syndrome and MeCP2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Autonomic dysfunction with mutations in the gene that encodes methyl-CpG-binding protein 2: insights into Rett syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Correction of respiratory disorders in a mouse model of Rett syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Sociability and motor functions in Shank1 mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Abnormalities of cell packing density and dendritic complexity in the MeCP2 A140V mouse model of Rett syndrome/X-linked mental retardation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Cognitive and social functions and growth factors in a mouse model of Rett syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Tests to assess motor phenotype in mice: a user's guide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

A novel hypomorphic MECP2 point mutation is associated with a neuropsychiatric phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Prepulse inhibition in fragile X syndrome: feasibility, reliability, and implications for treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

MeCP2, a key contributor to neurological disease, activates and represses transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Role of endogenous somatostatin in regulating GH output under basal conditions and in response to metabolic extremes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Ube3a mRNA and protein expression are not decreased in Mecp2R168X mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Autonomic cardiovascular control in methyl-CpG-binding protein 2 (Mecp2) deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Behavioral and anatomical abnormalities in Mecp2 mutant mice: a model for Rett syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Reversal of neurological defects in a mouse model of Rett syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Correlation between clinical severity in patients with Rett syndrome with a p.R168X or p.T158M MECP2 mutation, and the direction and degree of skewing of X-chromosome inactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Very mild cases of Rett syndrome with skewed X inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Mecp2 deficiency disrupts norepinephrine and respiratory systems in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Impaired passive avoidance learning in mice lacking central neuronal nicotinic acetylcholine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

X-chromosome inactivation patterns are unbalanced and affect the phenotypic outcome in a mouse model of rett syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Identification of MeCP2 mutations in a series of females with autistic disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Characterisation of breathing and associated central autonomic dysfunction in the Rett disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Dissecting the behaviour of transgenic mice: is it the mutation, the genetic background, or the environment?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Spectrum of mutations in the MECP2 gene in patients with infantile autism and Rett syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

A proposed test battery and constellations of specific behavioral paradigms to investigate the behavioral phenotypes of transgenic and knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

On a unusual brain atrophy syndrome in hyperammonemia in childhood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Rett's syndrome: prevalence and impact on progressive severe mental retardation in girls.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

Gating and habituation of the startle reflex in schizophrenic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522402

20 June 2018

The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Mild overexpression of MeCP2 causes a progressive neurological disorder in mice.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Evidence for abnormal early development in a mouse model of Rett syndrome.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Targeted delivery of an Mecp2 transgene to forebrain neurons improves the behavior of female Mecp2-deficient mice.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Effect of inspired oxygen on periodic breathing in methy-CpG-binding protein 2 (Mecp2) deficient mice.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Early environmental enrichment moderates the behavioral and synaptic phenotype of MeCP2 null mice.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Anxiety-related behaviors in the elevated zero-maze are affected by genetic factors and retinal degeneration

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Sensorimotor gating deficits in adults with autism

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Impaired sensorimotor gating of the acoustic startle response in the prodrome of schizophrenia

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Social impairments in Rett syndrome: characteristics and relationship with clinical severity.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Preserved speech variants of the Rett syndrome: molecular and clinical analysis.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

De novo MECP2 frameshift mutation in a boy with moderate mental retardation, obesity and gynaecomastia.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Study of MECP2 gene in Rett syndrome variants and autistic girls.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDS406

21 January 2018

Mutant mice and neuroscience: recommendations concerning genetic background. Banbury Conference on genetic background in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23026749

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autonomic nervous system dysregulation: breathing and heart rate perturbation during wakefulness in young girls with Rett syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23026749

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased skewing of X chromosome inactivation in Rett syndrome patients and their mothers

1 reference

https://pubmed.ncbi.nlm.nih.gov/23026749

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early breathing defects after moderate hypoxia or hypercapnia in a mouse model of Rett syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23026749

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linking MECP2 and pain sensitivity: the example of Rett syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/23026749

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDS406

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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