(Q33922865)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10818674%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

review article

1 reference

title

Selective inhibitors of cyclooxygenase-2 (COX-2) (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10818674%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

author name string

J J Talley

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10818674%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

publication date

1 January 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10818674%20AND%20SRC:MED&resulttype=core&format=json

Progress in medicinal chemistry

6 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10818674%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

volume

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10818674%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

page(s)

201-234

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10818674%20AND%20SRC:MED&resulttype=core&format=json

Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs

6 November 2019

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Association of upper gastrointestinal toxicity of non-steroidal anti-inflammatory drugs with continued exposure: cohort study

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7 January 2021

The effect of Helicobacter pylori infection on NSAID-related gastroduodenal damage in the elderly

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7 January 2021

Renal syndromes associated with nonsteroidal antiinflammatory drugs

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7 January 2021

Renal side effects of nonsteroidal antiinflammatory drugs: clinical relevance

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7 January 2021

Non-steroidal anti-inflammatory drug-induced renal failure: a brief review of the role of cyclo-oxygenase isoforms

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7 January 2021

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs

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7 January 2021

cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase

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7 January 2021

Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing

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7 January 2021

Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues

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7 January 2021

Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme

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7 January 2021

Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic

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7 January 2021

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain

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7 January 2021

Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis

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7 January 2021

Human cyclooxygenase-2 cDNA

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7 January 2021

Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase

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7 January 2021

Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo

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7 January 2021

Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase

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7 January 2021

New insights into the mode of action of anti-inflammatory drugs.

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7 January 2021

Constitutive cyclooxygenase (COX-1) and inducible cyclooxygenase (COX-2): rationale for selective inhibition and progress to date

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7 January 2021

Prostaglandin synthase 2.

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7 January 2021

Cyclo-oxygenase and colon cancer: clues to the aspirin effect?

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7 January 2021

Inhibitory effect of NS-398, a selective cyclooxygenase-2 inhibitor, on azoxymethane-induced aberrant crypt foci in colon carcinogenesis of F344 rats.

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7 January 2021

Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2.

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7 January 2021

Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system

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7 January 2021

A human whole blood assay for clinical evaluation of biochemical efficacy of cyclooxygenase inhibitors

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7 January 2021

High-level expression of active human cyclooxygenase-2 in insect cells

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7 January 2021

Characterization of autocrine inducible prostaglandin H synthase-2 (PGHS-2) in human osteosarcoma cells

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7 January 2021

Meloxicam: influence on arachidonic acid metabolism. Part 1. In vitro findings

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7 January 2021

Mechanism of selective inhibition of human prostaglandin G/H synthase-1 and -2 in intact cells

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7 January 2021

Inhibition of constitutive and inducible cyclooxygenase activity in human platelets and mononuclear cells by NSAIDs and Cox 2 inhibitors

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7 January 2021

Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase

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7 January 2021

Effect of inhibitor time-dependency on selectivity towards cyclooxygenase isoforms

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7 January 2021

Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor

1 reference

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7 January 2021

Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs

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7 January 2021

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

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7 January 2021

The effect of immunomodulating drugs on adjuvant-induced arthritis in Lewis rats

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7 January 2021

A structural feature of N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulfonamide (NS-398) that governs its selectivity and affinity for cyclooxygenase 2 (COX2)

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7 January 2021

Nimesulide. An update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy

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7 January 2021

The pharmacological profile of CGP 28238, a highly potent anti-inflammatory compound

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7 January 2021

Non-steroidal anti-inflammatories--XII. Mode of action of anti-inflammatory methane sulfonanilides

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7 January 2021

Cyclooxygenase-2 inhibitors. Synthesis and pharmacological activities of 5-methanesulfonamido-1-indanone derivatives

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7 January 2021

Mechanism of action of novel anti-inflammatory drugs diflumidone and R-805

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7 January 2021

Clinical trial with Nimesulide, a new non-steroid anti-inflammatory agent, in rheumatic pathology

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7 January 2021

Nimesulide in the short-term treatment of osteoarthrosis: a pilot study for assessing the minimal effective dose

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7 January 2021

Nimesulide in the short-term treatment of inflammatory process of dental tissues: a double-blind controlled trial against oxyphenbutazone

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7 January 2021

Nimesulide for the treatment of painful inflammatory process in the ear, nose and throat areas: a double-blind controlled study with benzydamine

1 reference

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7 January 2021

Differentiation-associated expression of prostaglandin G/H synthase in monocytic cells

1 reference

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7 January 2021

Studies on antiinflammatory agents. I. Synthesis and pharmacological properties of 2'-phenoxymethanesulfonanilide derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Carrageenan foot edema test

1 reference

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7 January 2021

Diaryloxazole and Diarylthiazolealkanoic Acids: Two Novel Series of Non-steroidal Anti-inflammatory Agents

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Anti-inflammatory properties of 4,5-diphenyl-2-oxazolepropionic acid (oxaprozin).

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Synthesis and platelet aggregation inhibitory activity of 4,5-bis(aryl)-2-substituted-thiazoles

1 reference

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7 January 2021

Nonprostanoid prostacyclin mimetics. 2. 4,5-Diphenyloxazole derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Nonprostanoid prostacyclin mimetics. 3. Structural variations of the diphenyl heterocycle moiety

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7 January 2021

Preparation and antiinflammatory activity of some nonacidic trisubstituted imidazoles

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Preparation and antiarthritic and analgesic activity of 4,5-diaryl-2-(substituted thio)-1H-imidazoles and their sulfoxides and sulfones

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxalin: anti-inflammatory without gastropathy?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Synthesis and biological activity of the metabolites of [3,4-bis(4-methoxyphenyl)-5-isoxazolyl]acetic acid

1 reference

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7 January 2021

Simultaneous quantification of an anti-inflammatory compound (DuP 697) and a potential metabolite (X6882) in human plasma and urine by high-performance liquid chromatography

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7 January 2021

Studies on anti-inflammatory agents. VI. Synthesis and pharmacological properties of 2,3-diarylthiophenes

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7 January 2021

Selective cyclooxygenase inhibitors: novel 1,2-diarylcyclopentenes are potent and orally active COX-2 inhibitors

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7 January 2021

1,2-Diarylcyclopentenes as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents

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7 January 2021

Diarylspiro[2.4]heptenes as orally active, highly selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationships

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7 January 2021

1,2-Diarylpyrroles as potent and selective inhibitors of cyclooxygenase-2

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Antiinflammatory 4,5-diarylpyrroles: synthesis and QSAR

1 reference

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7 January 2021

Antiinflammatory 4,5-diarylpyrroles. 2. Activity as a function of cyclooxygenase-2 inhibition

1 reference

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7 January 2021

1,2-Diarylimidazoles as potent, cyclooxygenase-2 selective, and orally active antiinflammatory agents

1 reference

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7 January 2021

Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).

1 reference

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7 January 2021

Novel terphenyls as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents

1 reference

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7 January 2021

Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site

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7 January 2021

Closing in on a stomach-sparing aspirin substitute

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https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2

1 reference

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7 January 2021

The cyclooxygenase-2 structure: new drugs for an old target?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

In vitro and in vivo pharmacological evidence of selective cyclooxygenase-2 inhibition by nimesulide: an overview

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7 January 2021

Pharmacology of meloxicam, a new non-steroidal anti-inflammatory drug with an improved safety profile through preferential inhibition of COX-2.

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7 January 2021

Meloxicam: a selective COX-2 inhibitor non-steroidal anti-inflammatory drug

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7 January 2021

A review of the clinical pharmacokinetics of meloxicam

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7 January 2021

Meloxicam: selective COX-2 inhibition in clinical practice

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https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Meloxicam in osteoarthritis: a 6-month, double-blind comparison with diclofenac sodium

1 reference

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7 January 2021

A double-blind, three-week study to compare the efficacy and safety of meloxicam 7.5 mg and meloxicam 15 mg in patients with rheumatoid arthritis

1 reference

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7 January 2021

A 4-week, double-blind, parallel-group study to compare the gastrointestinal effects of meloxicam 7.5 mg, meloxicam 15 mg, piroxicam 20 mg and placebo by means of faecal blood loss, endoscopy and symptom evaluation in healthy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6468%2808%2970048-1

7 January 2021

Adult human colonic subepithelial myofibroblasts express extracellular matrix proteins and cyclooxygenase-1 and -2

1 reference

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7 January 2021

10.1016/S0079-6468(08)70048-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10818674%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference