(Q33931176)

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The nuclear receptor peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24898257%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

The nuclear receptor peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24898257%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

endoplasmic reticulum

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cellular senescence

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based on heuristic

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1

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19 March 2020

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24898257%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Christina H Ferry

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Christina H Ferry

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19 March 2020

Nicholas Blazanin

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Nicholas Blazanin

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19 March 2020

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Lauren K Markell

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19 March 2020

Adam B Glick

5

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19 March 2020

Frank J Gonzalez

6

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19 March 2020

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4 June 2014

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19 March 2020

Journal of Biological Chemistry

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19 March 2020

289

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19 March 2020

29

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19 March 2020

20102-20119

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Europe PubMed Central

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19 March 2020

PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiation

1 reference

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5 July 2018

Peroxisome proliferator-activated receptor β/δ cross talks with E2F and attenuates mitosis in HRAS-expressing cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Stable over-expression of PPARβ/δ and PPARγ to examine receptor signaling in human HaCaT keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

The Unfolded Protein Response, Degradation from Endoplasmic Reticulum and Cancer

1 reference

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5 July 2018

Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Chemoprevention of chemically induced skin tumorigenesis by ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Activation of forkhead box O transcription factors by oncogenic BRAF promotes p21cip1-dependent senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Methods for monitoring endoplasmic reticulum stress and the unfolded protein response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Effect of ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in human lung cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta) inhibits chemically induced skin tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Many roads lead to oncogene-induced senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Endoplasmic reticulum stress in disease pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Targeting the mTOR signaling network in cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

AKT/PKB signaling: navigating downstream

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

XBP-1, a key regulator of unfolded protein response, activates transcription of IGF1 and Akt phosphorylation in zebrafish embryonic cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

GRP78 induction in cancer: therapeutic and prognostic implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Tumour biology: senescence in premalignant tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Mitogen stimulation cooperates with telomere shortening to activate DNA damage responses and senescence signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Smad3 regulates senescence and malignant conversion in a mouse multistage skin carcinogenesis model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Development of murine epidermal cell lines which contain an activated rasHa oncogene and form papillomas in skin grafts on athymic nude mouse hosts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Development of an in vitro model to study carcinogen-induced neoplastic progression of initiated mouse epidermal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106326

5 July 2018

Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.551069

21 January 2018

Peroxisome proliferator-activated receptor beta (delta)-dependent regulation of ubiquitin C expression contributes to attenuation of skin carcinogenesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.551069

21 January 2018

Inhibition of chemically induced skin carcinogenesis by sulindac is independent of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.551069

21 January 2018

A negative feedback signaling network underlies oncogene-induced senescence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.551069

21 January 2018

Mouse skin cells resistant to terminal differentiation associated with initiation of carcinogenesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.551069

21 January 2018

Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.551069

21 January 2018

Differential endoplasmic reticulum stress signaling pathways mediated by iNOS.

1 reference

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21 January 2018

Transcriptome profile of human colorectal adenomas.

1 reference

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21 January 2018

Stress-regulated transcription factor ATF4 promotes neoplastic transformation by suppressing expression of the INK4a/ARF cell senescence factors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.551069

21 January 2018

[1] Isolation and utilization of epidermal keratinocytes for oncogene research

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.551069

21 January 2018

Rapamycin inhibits constitutive p70s6k phosphorylation, cell proliferation, and colony formation in small cell lung cancer cells

1 reference

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29 October 2018

p16(INK4a) expression begins early in human colon neoplasia and correlates inversely with markers of cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24898257

12 December 2020

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10.1074/JBC.M114.551069

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24898257%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24898257%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24898257%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

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