(Q33933969)

30 July 2017

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease (English)

1 reference

30 July 2017

0 references

4

S B Prusiner

1 reference

30 July 2017

3

F E Cohen

1 reference

30 July 2017

C Korth

1

1 reference

PubMed ID

11504948

30 July 2017

B C May

series ordinal

2

1 reference

PubMed ID

11504948

30 July 2017

language of work or name

English

0 references

publication date

1 August 2001

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

1 reference

30 July 2017

98

1 reference

30 July 2017

17

1 reference

30 July 2017

9836-9841

1 reference

Shattuck lecture--neurodegenerative diseases and prions

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Mimicking dominant negative inhibition of prion replication through structure-based drug design

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Cultured cell sublines highly susceptible to prion infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Porphyrin and phthalocyanine antiscrapie compounds.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Elimination of prions by branched polyamines and implications for therapeutics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Is schizophrenia a neurodegenerative disorder? A clinical and neurobiological perspective

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

The anti-prion activity of Congo red. Putative mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Congo red prolongs the incubation period in scrapie-infected hamsters.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Glycolipid-anchored proteins in neuroblastoma cells form detergent-resistant complexes without caveolin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Novel proteinaceous infectious particles cause scrapie

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Influence of aminasine on experimental scrapie in mice.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Does the agent of scrapie replicate without nucleic acid?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Concentration and distribution of thioridazine and metabolites in schizophrenic post-mortem brain tissue

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Biological evidence that scrapie agent has an independent genome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Suppression of scrapie infection in mice by heteropolyanion 23, dextran sulfate, and some other polyanions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Chemoprophylaxis of scrapie in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Potent inhibition of scrapie-associated PrP accumulation by congo red

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Unconventional Viruses and the Origin and Disappearance of Kuru

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. The Tacrine Study Group.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Scrapie prions aggregate to form amyloid-like birefringent rods

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55539

Nucleic acids in prion preparations: unspecific background or essential component?

29 October 2018

1 reference

12 December 2020

Deaths from variant Creutzfeldt-Jakob disease

1 reference

12 December 2020

[Therapeutic method derived from hiberno-therapy in excitation and agitation states]

1 reference

12 December 2020

[Present technic of artificial hibernation]

1 reference

12 December 2020

Inhibition of Trypanosoma cruzi trypanothione reductase by acridines: kinetic studies and structure-activity relationships

1 reference

12 December 2020

Scrapie incubation time can exceed natural lifespan

1 reference

12 December 2020

The antiviral compound HPA-23 can prevent scrapie when administered at the time of infection

1 reference

12 December 2020

Dextran Sulphate 500 Delays and Prevents Mouse Scrapie by Impairment of Agent Replication in Spleen

1 reference

12 December 2020

Inactivation of the scrapie agent by ultraviolet irradiation in the presence of chlorpromazine

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.161274798

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference

PubMed ID

11504948