(Q33941028)

30 July 2017

title

High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis (English)

1 reference

30 July 2017

10

Etienne Pays

0 references

Benoît Stijlemans

1

Benoît Stijlemans

1 reference

ORCID Public Data File 2021

Guy Caljon

2

Guy Caljon

0 references

Patrick De Baetselier

13

Patrick De Baetselier

0 references

Alexandros Nikolaou

Alexandros Nikolaou

8

0 references

Dirk Saerens

Dirk Saerens

4

0 references

David Pérez-Morga

David Pérez-Morga

6

0 references

Stefan Magez

Stefan Magez

11

0 references

Mark C. Field

Mark C Field

12

0 references

Serge Muyldermans

Serge Muyldermans

14

0 references

author name string

Senthil Kumar A Natesan

3

1 reference

30 July 2017

Katja Conrath

5

1 reference

30 July 2017

Jeremy N Skepper

7

1 reference

30 July 2017

Lea Brys

9

1 reference

30 July 2017

publication date

16 June 2011

1 reference

30 July 2017

1 reference

30 July 2017

volume

7

1 reference

30 July 2017

issue

6

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30 July 2017

page(s)

e1002072

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

16 June 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3116811/fullTextXML

inferred from PubMed Central ID database lookup

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Both of the Rab5 subfamily small GTPases of Trypanosoma brucei are essential and required for endocytosis.

5 July 2018

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Clathrin-mediated endocytosis is essential in Trypanosoma brucei.

5 July 2018

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Rab5 and Rab11 mediate transferrin and anti-variant surface glycoprotein antibody recycling in Trypanosoma brucei

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5 July 2018

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5 July 2018

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Mechanism for antibody catalysis of the oxidation of water by singlet dioxygen

5 July 2018

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Differential endocytic functions of Trypanosoma brucei Rab5 isoforms reveal a glycosylphosphatidylinositol-specific endosomal pathway.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Rab11 regulates the compartmentalization of early endosomes required for efficient transport from early endosomes to the trans-golgi network

5 July 2018

1 reference

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Antibodies have the intrinsic capacity to destroy antigens

5 July 2018

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5 July 2018

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Both IgM and IgG anti-VSG antibodies initiate a cycle of aggregation-disaggregation of bloodstream forms of Trypanosoma brucei without damage to the parasite

5 July 2018

1 reference

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Multiple mechanisms of immune evasion by African trypanosomes

5 July 2018

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5 July 2018

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A new method for the rapid purification of both the membrane-bound and released forms of the variant surface glycoprotein from Trypanosoma brucei

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116811

Quantification of endocytosis-derived membrane traffic

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116811

The electrochemical proton gradient in the bloodstream form of Trypanosoma brucei is dependent on the temperature

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116811

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116811

Inactivation or elimination of potentially trypanolytic, complement-activating immune complexes by pathogenic trypanosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116811

Hydrodynamic Flow-Mediated Protein Sorting on the Cell Surface of Trypanosomes

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002072

Accumulation of a GPI-anchored protein at the cell surface requires sorting at multiple intracellular levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002072

Kinetics of endocytosis and recycling of the GPI-anchored variant surface glycoprotein in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002072

Trypanosome glucose transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002072

Prevalence of Trypanosoma evansi infection and associated risk factors in camels in eastern Chad

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002072

Antibody catalysis of the oxidation of water

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002072

Killing of African trypanosomes by antimicrobial peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002072

Neuropeptides kill African trypanosomes by targeting intracellular compartments and inducing autophagic-like cell death.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002072

Flagellar motility is required for the viability of the bloodstream trypanosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002072

Triazinyl derivatives that are potent inhibitors of glucose transport in Trypanosoma brucei.

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116811

Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor

29 October 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002072

Studies on the recycling of the transferrin receptor in Trypanosoma brucei using an inducible gene expression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002072

Characterization of D-glucose transport in Trypanosoma rangeli

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002072

Dissociation of IgG antibody-mediated clumps ofTrypanosoma brucei gambiense by complement

21 January 2018

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12 December 2020

Trypanosoma congolense bloodstream forms evade complement lysis in vitro by shedding of immune complexes

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12 December 2020

Mechanisms for the elimination of potentially lytic complement-fixing variable surface glycoprotein antibody-complexes in Trypanosoma brucei

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12 December 2020

Degradation, recycling, and shedding of Trypanosoma brucei variant surface glycoprotein

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12 December 2020

The interaction of Trypanosoma brucei with antibodies to variant surface glycoproteins

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12 December 2020

10.1371/JOURNAL.PPAT.1002072

Identifiers

DOI

1 reference

30 July 2017

1 reference

30 July 2017

1 reference