(Q33941047)

30 July 2017

2 references

25 October 2022

10 January 2024

"Rational vaccine design" for HIV should take into account the adaptive potential of polyreactive antibodies (English)

1 reference

human immunodeficiency virus infectious disease

30 July 2017

main subject

1 reference

17 August 2020

1 reference

19 September 2019

1 reference

3 November 2019

1 reference

17 August 2020

physiological adaptation

1 reference

21 December 2020

1 reference

Jordan D Dimitrov

1

0 references

Sébastien Lacroix-Desmazes

object named as

Sebastien Lacroix-Desmazes

series ordinal

4

0 references

Srini V Kaveri

series ordinal

3

object named as

Srinivas V Kaveri

1 reference

30 July 2017

2

Michel D Kazatchkine

1 reference

30 July 2017

1 reference

language of work or name

1 reference

16 June 2011

1 reference

30 July 2017

1 June 2011

13 references

23 March 2019

20 June 2019

20 August 2019

13 September 2019

19 September 2019

19 October 2019

3 November 2019

1 July 2020

17 August 2020

21 December 2020

22 August 2022

25 October 2022

10 January 2024

14 references

30 July 2017

23 March 2019

20 June 2019

20 August 2019

13 September 2019

19 September 2019

19 October 2019

3 November 2019

1 July 2020

17 August 2020

21 December 2020

22 August 2022

25 October 2022

10 January 2024

7

1 reference

30 July 2017

issue

6

1 reference

30 July 2017

page(s)

e1002095

1 reference

Creative Commons Attribution 4.0 International

30 July 2017

copyright license

2 references

25 October 2022

on focus list of Wikimedia project

10 January 2024

1 reference

ScienceSource

0 references

cites work

Evolving concepts of specificity in immune reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Protein binding specificity versus promiscuity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

The importance of natural IgM: scavenger, protector and regulator

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Carbohydrate targets in HIV vaccine research: lessons from failures.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Few and far between: how HIV may be evading antibody avidity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Molecular description of flexibility in an antibody combining site

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

The role of antibodies in HIV vaccines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Aromatic residues at the edge of the antibody combining site facilitate viral glycoprotein recognition through membrane interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

HIV-1 and influenza antibodies: seeing antigens in new ways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

The broad antibacterial activity of the natural antibody repertoire is due to polyreactive antibodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

GP120: target for neutralizing HIV-1 antibodies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Polyreactivity of antibody molecules

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Protein dynamics and the immunological evolution of molecular recognition.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Antibody neutralization and escape by HIV-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Antibody multispecificity mediated by conformational diversity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Differences in electrostatic properties at antibody-antigen binding sites: implications for specificity and cross-reactivity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

The primary antibody repertoire represents a linked network of degenerate antigen specificities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Thermodynamic analyses reveal role of water release in epitope recognition by a monoclonal antibody against the human guanylyl cyclase C receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Thermodynamic analysis of biomolecular interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Structural insights into the evolution of an antibody combining site

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Low levels of HIV-1 infection in cutaneous dendritic cells promote extensive viral replication upon binding to memory CD4+ T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3116824

Pushing the envelope on HIV-1 neutralization

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002095

Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002095

Conformational flexibility and kinetic complexity in antibody-antigen interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002095

Concanavalin A binding to HIV envelope protein is less sensitive to mutations in glycosylation sites than monoclonal antibody 2G12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002095

Thermodynamics of Fab-ssDNA interactions: contribution of heavy chain complementarity determining region 3

21 January 2018

1 reference

12 December 2020

Control of early viral and bacterial distribution and disease by natural antibodies

1 reference

12 December 2020

Maturation of an antibody response is governed by modulations in flexibility of the antigen-combining site

1 reference

12 December 2020

Mutations of an epitope hot-spot residue alter rate limiting steps of antigen-antibody protein-protein associations

1 reference

12 December 2020

Conformational diversity and protein evolution--a 60-year-old hypothesis revisited

1 reference

12 December 2020

Spectroscopic, calorimetric, and kinetic demonstration of conformational adaptation in peptide-antibody recognition

1 reference

12 December 2020

Enthalpy–entropy compensation in the transition of a monospecific antibody towards antigen-binding promiscuity

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1002095

Identifiers

DOI

1 reference

30 July 2017

1 reference

30 July 2017

1 reference