(Q33945492)

30 July 2017

1 reference

title

Purine nucleoside phosphorylases: properties, functions, and clinical aspects (English)

1 reference

30 July 2017

Bzowska A

1

1 reference

PubMed ID

11337031

30 July 2017

Kulikowska E

series ordinal

2

1 reference

PubMed ID

11337031

30 July 2017

Shugar D

series ordinal

3

1 reference

30 July 2017

1 December 2000

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Pharmacology & Therapeutics

30 July 2017

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30 July 2017

88

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30 July 2017

3

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30 July 2017

349-425

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Deoxyribosyl exchange activity associated with nucleoside phosphorylase

30 July 2017

1 reference

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7 January 2021

Determination of purine nucleoside phosphorylase activity in human erythrocytes by capillary electrophoresis

1 reference

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7 January 2021

Determination of purine enzyme activities in human erythrocytes by capillary electrophoresis

1 reference

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7 January 2021

Purine nucleoside phosphorylase. VI. Microheterogeneity and comparison of kinetic behavior of the enzyme from several tissues and species

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7 January 2021

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Stable and inheritable changes in genotype and phenotype of albino melanocytes induced by an RNA-DNA oligonucleotide

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7 January 2021

Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori

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7 January 2021

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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Lentiviral vectors--the promise of gene therapy within reach?

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7 January 2021

The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A resolution provides insights into substrate binding and catalysis

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7 January 2021

Mitochondrial basis for immune deficiency. Evidence from purine nucleoside phosphorylase-deficient mice

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7 January 2021

In vivo and in vitro pharmacologic activity of the purine nucleoside phosphorylase inhibitor BCX-34: the role of GTP and dGTP

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7 January 2021

Guanine, pyrazolo[3,4-d]pyrimidine, and triazolo[4,5-d]pyrimidine (8-azaguanine) phosphonate acyclic derivatives as inhibitors of purine nucleoside phosphorylase

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7 January 2021

Efficacy of pyrazolopyrimidine ribonucleosides against Trypanosoma cruzi: studies in vitro and in vivo with sensitive and resistant strains.

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Purine pathway enzymes in the circulating malignant cells of patients with cutaneous T-cell lymphoma

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7 January 2021

Evidence for a pathway independent from 2'-deoxyguanosine and reversible by IL-2 by which purine nucleoside phosphorylase inhibitors block T-cell proliferation

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7 January 2021

Rational design of enzyme inhibitors: multisubstrate analogue inhibitors

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7 January 2021

Correction of purine nucleoside phosphorylase deficiency by transplantation of allogeneic bone marrow from a sibling

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7 January 2021

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Novel 6-alkoxypurine 2',3'-dideoxynucleosides as inhibitors of the cytopathic effect of the human immunodeficiency virus

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7 January 2021

A second purine nucleoside phosphorylase in Escherichia coli K-12. I. Xanthosine phosphorylase regulatory mutants isolated as secondary-site revertants of a deoD mutant

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7 January 2021

2-Chloro-2'-deoxyadenosine (cladribine) and its analogues are good substrates and potent selective inhibitors of Escherichia coli purine-nucleoside phosphorylase

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7 January 2021

Properties of purine nucleoside phosphorylase (PNP) of mammalian and bacterial origin

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7 January 2021

Acyclonucleoside analogue inhibitors of mammalian purine nucleoside phosphorylase

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7 January 2021

Formycins A and B and some analogues: selective inhibitors of bacterial (Escherichia coli) purine nucleoside phosphorylase

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7 January 2021

Linear free energy relationships for N(7)-substituted guanosines as substrates of calf spleen purine nucleoside phosphorylase. Possible role of N(7)-protonation as an intermediary in phosphorolysis

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7 January 2021

Purine nucleoside phosphorylase: inhibition by purine N(7)- and N(9)-acyclonucleosides; and substrate properties of 7-beta-D-ribofuranosylguanine and 7-beta-D-ribofuranosylhypoxanthine

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7 January 2021

Calf spleen purine nucleoside phosphorylase: purification, sequence and crystal structure of its complex with an N(7)‐acycloguanosine inhibitor

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7 January 2021

Kinetics of phosphorolysis of 3-(beta-D-ribofuranosyl)adenine and 3-(beta-D-ribofuranosyl)hypoxanthine, non-conventional substrates of purine-nucleoside phosphorylase.

1 reference

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7 January 2021

Crystallization and preliminary X-ray studies of purine nucleoside phosphorylase from Cellulomonas sp

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7 January 2021

Synthesis of 6-aryloxy- and 6-arylalkoxy-2-chloropurines and their interactions with purine nucleoside phosphorylase from Escherichia coli

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7 January 2021

Extremely thermophilic and thermostable 5'-methylthioadenosine phosphorylase from the archaeon Sulfolobus solfataricus. Gene cloning and amino acid sequence determination

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7 January 2021

Heterologous expression of 5'-methylthioadenosine phosphorylase from the archaeon Sulfolobus solfataricus: characterization of the recombinant protein and involvement of disulfide bonds in thermophilicity and thermostability

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7 January 2021

In vitro assessment of salvage pathways for pyrimidine bases in rat liver and brain.

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7 January 2021

Thyroid purine nucleoside phosphorylase. II. Kinetic model by alternate substrate and inhibition studies

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7 January 2021

Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s)

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7 January 2021

A new isotopic assay for purine nucleoside phosphorylase

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7 January 2021

A continuous spectrophotometric assay for protein phosphatases

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7 January 2021

Purification and partial characterization of purine nucleoside phosphorylase from Serratia marcescens

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7 January 2021

A new colorimetric assay for purine nucleoside phosphorylase

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7 January 2021

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

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7 January 2021

Would suicide gene therapy solve the 'T-cell dilemma' of allogeneic bone marrow transplantation?

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7 January 2021

Correction of the mutation responsible for sickle cell anemia by an RNA-DNA oligonucleotide

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7 January 2021

Effects of a novel purine nucleoside phosphorylase inhibitor, BCX-34, on activation and proliferation of normal human lymphoid cells

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7 January 2021

Diagnostic uses of the Hill (logit and Nernst) plots

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7 January 2021

Gene therapy for cancer

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7 January 2021

The complete genome of the hyperthermophilic bacterium Aquifex aeolicus

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7 January 2021

Antitumor Potential of Acyclic Nucleoside Phosphonates

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7 January 2021

Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor

1 reference

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7 January 2021

Enzymic determination of inorganic phosphates, organic phosphates and phosphate-liberating enzymes by use of nucleoside phosphorylase-xanthine oxidase (dehydrogenase)-coupled reactions.

1 reference

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7 January 2021

Rational design of quinazoline-based irreversible inhibitors of human erythrocyte purine nucleoside phosphorylase

1 reference

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7 January 2021

PD 141955 and CI-972: 9-deazaguanine analog purine nucleoside phosphorylase inhibitors. II. Effects on nucleoside catabolism in human and rat blood in vitro

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7 January 2021

Mechanisms of 2'-deoxyguanosine toxicity in mouse T-lymphoma cells with purine nucleoside phosphorylase deficiency and resistance to inhibition of ribonucleotide reductase by dGTP.

1 reference

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7 January 2021

Characterization of Lactococcus lactis UV-sensitive mutants obtained by ISS1 transposition

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7 January 2021

Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

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7 January 2021

Inherited variants of human nucleoside phosphorylase

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7 January 2021

Malaria researchers wait for industry to join fight

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7 January 2021

Structure-based design of inhibitors of purine nucleoside phosphorylase. 3. 9-Arylmethyl derivatives of 9-deazaguanine substituted on the methylene group

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7 January 2021

Purine nucleoside phosphorylase. 2. Catalytic mechanism

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7 January 2021

Purine nucleoside phosphorylase. 1. Structure-function studies

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7 January 2021

Synthesis of Transition State Analogue Inhibitors for Purine Nucleoside Phosphorylase and N-Riboside Hydrolases

1 reference

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7 January 2021

Rapid determination of purine enzyme activity in intact and lysed cells using high-performance liquid chromatography with and without radiolabelled substrates

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7 January 2021

Structure-activity relationships for a class of inhibitors of purine nucleoside phosphorylase

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7 January 2021

Whole-genome random sequencing and assembly of Haemophilus influenzae Rd

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7 January 2021

Correction of purine nucleoside phosphorylase deficiency by retroviral-mediated gene transfer in mouse S49 T cell lymphoma: a model for gene therapy of T cell immunodeficiency

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7 January 2021

Phosphate determination by enzymatic colorimetric assay

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7 January 2021

The Minimal Gene Complement of Mycoplasma genitalium

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Complete Genome Sequence of Treponema pallidum, the Syphilis Spirochete

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7 January 2021

A quantitative histochemical procedure for the demonstration of purine nucleoside phosphorylase activity in rat and human liver using Tetranitro BT and xanthine oxidase as auxiliary enzyme.

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7 January 2021

Substrate specificities of 5'-deoxy-5'-methylthioadenosine phosphorylase from Trypanosoma brucei brucei and mammalian cells

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7 January 2021

ADA and PNP deficiencies: how it all began

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7 January 2021

Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity

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7 January 2021

Blockade of nucleoside degradation in monkey whole blood in vitro by CI-1000, a purine nucleoside phosphorylase (PNP) inhibitor.

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7 January 2021

Preliminary report on 8-amino-9-(2-thienylmethyl)guanine (PD 119,229), a novel and potent purine nucleoside phosphorylase inhibitor

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7 January 2021

Selective in vitro inhibition of human MOLT-4 T lymphoblasts by the novel purine nucleoside phosphorylase inhibitor, CI-972

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7 January 2021

Biochemical and Pharmacological Properties of CI-972, a Novel 9-Deazaguanine Analog Purine Nucleoside Phosphorylase (PNP) Inhibitor

1 reference

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7 January 2021

Comparative in vitro and in vivo activities of two 9-deazaguanine analog inhibitors of purine nucleoside phosphorylase, CI-972 and PD 141955

1 reference

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7 January 2021

Apoptotic death induced in MOLT-4 T-lymphoblasts by purine nucleoside phosphorylase inhibition

1 reference

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7 January 2021

Cloning of human purine-nucleoside phosphorylase cDNA sequences by complementation in Escherichia coli

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7 January 2021

Deficient cellular immunity--finding and fixing the defects

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7 January 2021

Structure-based design of inhibitors of purine nucleoside phosphorylase. 4. A study of phosphate mimics

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7 January 2021

Repairing the genome's spelling mistakes

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7 January 2021

Enzymic determination of inorganic phosphate in the presence of creatine phosphate

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7 January 2021

The partial purification and characterization of purine nucleoside phosphorylase from mammalian mitochondria

1 reference

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7 January 2021

Purine nucleoside phosphorylase: purification using an ether-linked formycin B/sepharose 6B resin with unusual properties.

1 reference

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7 January 2021

Pharmacokinetics/pharmacodynamics of CI-1000, a purine nucleoside phosphorylase (PNP) inhibitor, in rats and monkeys.

1 reference

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7 January 2021

Purification and characterization of purine nucleoside phosphorylase and pyrimidine nucleoside phosphorylase from Bacillus stearothermophilus TH 6-2.

1 reference

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7 January 2021

Cloning of purine nucleoside phosphorylase II gene from Bacillus stearothermophilus TH 6-2 and characterization of its gene product

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7 January 2021

Cloning and expression of purine nucleoside phosphorylase I gene from Bacillus stearothermophilus TH 6-2.

1 reference

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7 January 2021

A second purine nucleoside phosphorylase in Escherichia coli K-12. II. Properties of xanthosine phosphorylase and its induction by xanthosine

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7 January 2021

The enzymatic synthesis of antiviral agents

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7 January 2021

Analytical ultracentrifugation of complex macromolecular systems

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7 January 2021

A convenient synthesis of 2'-deoxy-2-fluoroadenosine; a potential prodrug for suicide gene therapy

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7 January 2021

A new spectrophotometric assay for enzymes of purine metabolism. III. Determination of purine nucleoside phosphorylases

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7 January 2021

Use of site-directed mutagenesis to enhance the epitope-shielding effect of covalent modification of proteins with polyethylene glycol

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7 January 2021

Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae

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7 January 2021

Retroviral-mediated gene therapy for the treatment of hepatocellular carcinoma: an innovative approach for cancer therapy

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7 January 2021

Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase

1 reference

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7 January 2021

Cell to cell contact is not required for bystander cell killing by Escherichia coli purine nucleoside phosphorylase

1 reference

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7 January 2021

Genetic analysis of purine metabolism in Leishmania donovani

1 reference

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7 January 2021

In vitro study of BCX-34: a new human T-lymphocyte-specific purine phosphorylase inhibitor

1 reference

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7 January 2021

Folding and association of oligomeric and multimeric proteins

1 reference

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7 January 2021

Purine-nucleoside phosphorylase from Salmonella typhimurium and Escherichia coli. Initial velocity kinetics, ligand banding, and reaction mechanism

1 reference

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7 January 2021

Two purine nucleoside phosphorylases in Bacillus subtilis. Purification and some properties of the adenosine-specific phosphorylase

1 reference

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7 January 2021

Purine Nucleoside Phosphorylase from Escherichia coli and Salmonella typhimurium. Purification and Some Properties

1 reference

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7 January 2021

Nucleotide sequence of murine purine nucleoside phosphorylase cDNA.

1 reference

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7 January 2021

Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII

1 reference

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7 January 2021

Sequence and functional characterization of the human purine nucleoside phosphorylase promoter

1 reference

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7 January 2021

Intron requirement for expression of the human purine nucleoside phosphorylase gene

1 reference

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7 January 2021

An enhancer in the first intron of the human purine nucleoside phosphorylase-encoding gene

1 reference

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7 January 2021

Retrovirus-Mediated Transduction of an Engineered Intron-Containing Purine Nucleoside Phosphorylase Gene

1 reference

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7 January 2021

Stereoelectronic factors in the binding of substrate analogs and inhibitors to purine nucleoside phosphorylase isolated from human erythrocytes

1 reference

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7 January 2021

Purification and characterization of purine nucleoside phosphorylase from developing embryos of Hyalomma dromedarii.

1 reference

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7 January 2021

Sequence Analysis of the Genome of the Unicellular Cyanobacterium Synechocystis sp. Strain PCC6803. II. Sequence Determination of the Entire Genome and Assignment of Potential Protein-coding Regions

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7 January 2021

Complete Sequence and Gene Organization of the Genome of a Hyper-thermophilic Archaebacterium, Pyrococcus horikoshii OT3

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7 January 2021

Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts

1 reference

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7 January 2021

9-[(Phosphonoalkyl)benzyl]guanines. Multisubstrate analogue inhibitors of human erythrocyte purine nucleoside phosphorylase

1 reference

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7 January 2021

[[(Guaninylalkyl)phosphinico]methyl]phosphonic acids. Multisubstrate analogue inhibitors of human erythrocyte purine nucleoside phosphorylase

1 reference

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7 January 2021

Binding of phosphate and sulfate anions by purine nucleoside phosphorylase from E. coli: ligand-dependent quenching of enzyme intrinsic fluorescence.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Substrate/inhibitor properties of human deoxycytidine kinase (dCK) and thymidine kinases (TK1 and TK2) towards the sugar moiety of nucleosides, including O'-alkyl analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Formycin A and its N-methyl analogues, specific inhibitors of E. coli purine nucleoside phosphorylase (PNP): induced tautomeric shifts on binding to enzyme, and enzyme-->ligand fluorescence resonance energy transfer.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Purine nucleoside phosphorylase. Inosine hydrolysis, tight binding of the hypoxanthine intermediate, and third-the-sites reactivity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Purine nucleoside phosphorylase. Catalytic mechanism and transition-state analysis of the arsenolysis reaction.

1 reference

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7 January 2021

Pre-steady-state transition-state analysis of the hydrolytic reaction catalyzed by purine nucleoside phosphorylase.

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

1 reference

7 January 2021

Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with hypoxanthine at 2.15 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Crystal structure of the ternary complex of E. coli purine nucleoside phosphorylase with formycin B, a structural analogue of the substrate inosine, and phosphate (Sulphate) at 2.1 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Purification and properties of inosine-guanosine phosphorylase from Escherichia coli K-12.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Pyrimidine ribonucleoside phosphorylase activity vs 5- and/or 6-substituted uracil and uridine analogues, including conformational aspects

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Correlation of substrate-stabilization patterns with proposed mechanisms for three nucleoside phosphorylases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Purine nucleoside synthesis, an efficient method employing nucleoside phosphorylases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Properties of two unusual, and fluorescent, substrates of purine-nucleoside phosphorylase: 7-methylguanosine and 7-methylinosine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Antiviral acyclic nucleoside phosphonate analogues as inhibitors of purine nucleoside phosphorylase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

The complete genome sequence of the gram-positive bacterium Bacillus subtilis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Investigation of alpha-deuterium kinetic isotope effects on the purine nucleoside phosphorylase reaction by the equilibrium-perturbation technique

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Development of an Assay Method for Purine Catabolic Enzymes in the Mouse and Its Adaptation for Use on an Autoanalyzer

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Rabbit brain purine nucleoside phosphorylase. Physical and chemical properties. Inhibition studies with aminopterin, folic acid and structurally related compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Bovine brain purine-nucleoside phosphorylase purification, characterization, and catalytic mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Calf spleen purine nucleoside phosphorylase: structure of its ternary complex with an N(7)-acycloguanosine inhibitor and a phosphate anion

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Simultaneous assay of adenosine deaminase and purine nucleoside phosphorylase activity as possible biochemical means to detect non-Hodgkin lymphomas of the oral cavity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

A set of independent selectable markers for transfection of the human malaria parasite Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Mutations in purine nucleoside phosphorylase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

In vivo gene therapy for prostate cancer: preclinical evaluation of two different enzyme-directed prodrug therapy systems delivered by identical adenovirus vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Ribose 1-phosphate and inosine activate uracil salvage in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

In vitro recycling of alpha-D-ribose 1-phosphate for the salvage of purine bases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

The enantioselectivity of enzymes involved in current antiviral therapy using nucleoside analogues: a new strategy?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Design of an adenosine phosphorylase by active-site modification of murine purine nucleoside phosphorylase. Enzyme kinetics and molecular dynamics simulation of Asn-243 and Lys-244 substitutions of purine nucleoside phosphorylase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Acholeplasma laidlawii B-PG9 adenine-specific purine nucleoside phosphorylase that accepts ribose-1-phosphate, deoxyribose-1-phosphate, and xylose-1-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Expression of a cDNA sequence encoding human purine nucleoside phosphorylase in rodent and human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Human purine nucleoside phosphorylase and adenosine deaminase: gene transfer into cultured cells and murine hematopoietic stem cells by using recombinant amphotropic retroviruses

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Continuous monitoring of Pi release following nucleotide hydrolysis in actin or tubulin assembly using 2-amino-6-mercapto-7-methylpurine ribonucleoside and purine-nucleoside phosphorylase as an enzyme-linked assay.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Trypanosoma cruzi adenine nucleoside phosphorylase. Purification and substrate specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Gene therapy of hepatocellular carcinoma in vitro and in vivo in nude mice by adenoviral transfer of the Escherichia coli purine nucleoside phosphorylase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Purine nucleoside phosphorylase: a target for drug design

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(arylmethyl) derivatives of 9-deazaguanine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Phosphorolytic and ribosyl transfer mechanisms of purified chicken liver purine nucleoside phosphorylase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Atomic structure at 2.5 A resolution of uridine phosphorylase from E. coli as refined in the monoclinic crystal lattice

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Characterization of purine nucleoside phosphorylase in leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Inhibitors of the enzyme purine nucleoside phosphorylase as potential therapy for psoriasis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Synthesis and biological activity of a novel class of purine nucleoside phosphorylase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Gene therapy: the first decade

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Purification and characterization of a purine-nucleoside phosphorylase from bovine thyroid

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Crystallization and some properties of purine nucleoside phosphorylase from chicken liver

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Purine nucleoside phosphorylase of chicken liver

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Unexpected sequence similarity between nucleosidases and phosphoribosyltransferases of different specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Difference in onset of warm ischemia and reperfusion injury between parenchymal and endothelial cells of the liver. Evaluation by purine nucleoside phosphorylase and hyaluronic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Refined structure of purine nucleoside phosphorylase at 2.75 A resolution.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Foamy virus vectors for suicide gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Purine nucleoside phosphorylase: its use in a spectroscopic assay for inorganic phosphate and for removing inorganic phosphate with the aid of phosphodeoxyribomutase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Efficacy of hypothermic perfusion using University of Wisconsin solution in extended hepatectomy with hepatic inflow occlusion in a canine model

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Design of vectors for efficient expression of human purine nucleoside phosphorylase in skin fibroblasts from enzyme-deficient humans

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Two novel missense and frameshift mutations in exons 5 and 6 of the purine nucleoside phosphorylase (PNP) gene in a severe combined immunodeficiency (SCID) patient

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

In vivo gene therapy of cancer with E. coli purine nucleoside phosphorylase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Metabolism and metabolic actions of 6-methylpurine and 2-fluoroadenine in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Cloning and characterization of mouse deoxyguanosine kinase. Evidence for a cytoplasmic isoform

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

A purine nucleoside phosphorylase (PNP) inhibitor induces apoptosis via caspase-3-like protease activity in MOLT-4 T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Thymidine kinase-deleted vaccinia virus expressing purine nucleoside phosphorylase as a vector for tumor-directed gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Purine nucleoside phosphorylase: a new marker for free oxygen radical injury to the endothelial cell

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Comparison of super-secondary structures in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Changes in monkey plasma purines induced by repeated doses of CI-1000, a novel inhibitor of purine nucleoside phosphorylase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Allosteric regulation of purine nucleoside phosphorylase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Assay of inorganic phosphate in the mild pH range, suitable for measurement of glycogen phosphorylase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

31P NMR studies on purine nucleoside phosphorylases: determination of the scissile bond and of the equilibrium constant

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Direct evidence of autosomal recessive inheritance of Arg24 to termination codon in purine nucleoside phosphorylase gene in a family with a severe combined immunodeficiency patient

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Rabbit erythrocyte purine nucleoside phosphorylase. Initial-velocity studies

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Enzymatic N-riboside scission in RNA and RNA precursors.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Enzymatic transition-state analysis and transition-state analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

An enzymic method for the measurement of inorganic phosphate.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

New revolutions in the evolution of analytical ultracentrifugation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Structure-based design of inhibitors of purine nucleoside phosphorylase. 2. 9-Alicyclic and 9-heteroalicyclic derivatives of 9-deazaguanine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Gene therapy of cancer: activation of nucleoside prodrugs with E. coli purine nucleoside phosphorylase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Identification and characterization of genes (xapA, xapB, and xapR) involved in xanthosine catabolism in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

A specific adenosine phosphorylase, distinct from purine nucleoside phosphorylase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

A continuous spectrophotometric method for the determination of glycogen phosphorylase-catalyzed reaction in the direction of glycogen synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-å crystal structure

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Purifications and properties of orotidine-phosphorolyzing enzyme and purine nucleoside phosphorylase from Erwinia carotovora AJ 2992

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Production of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine from 2',3'-dideoxyuridine and the corresponding purine bases by resting cells of Escherichia coli AJ 2595.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

In situ enzymatic removal of orthophosphate by the nucleoside phosphorylase catalyzed phosphorolysis of nicotinamide riboside.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Viral and host-cell protein kinases: enticing antiviral targets and relevance of nucleoside, and viral thymidine, kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

8-Amino-9-substituted guanines: potent purine nucleoside phosphorylase (PNP) inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Inhibition of the enzyme purine nucleoside phosphorylase (PNP) reduces refractoriness to transfused platelets in a dog model

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Secondary loss of deoxyguanosine kinase activity in purine nucleoside phosphorylase deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Point mutations at the purine nucleoside phosphorylase locus impair thymocyte differentiation in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Rational design of novel antimicrobials: blocking purine salvage in a parasitic protozoan

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Inhibition of human purine nucleoside phosphorylase by acyclic nucleosides and nucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

72 Purine nucleoside phosphorylase from human erythrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Purine nucleoside phosphorylase from human erythrocytes: physicochemical properties of the crystalline enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Human erythrocytic purine nucleoside phosphorylase: reaction with sugar-modified nucleoside substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Inhibitors of purine nucleoside phosphorylase, C(8) and C(5') substitutions

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Purine nucleoside phosphorylase. 3. Reversal of purine base specificity by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

7-Ribosyl-3-deazaguanine--mechanism of antibacterial action.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

An enzymic method for the determination of inorganic phosphate in serum

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Molecular cloning and nucleotide sequence of purine nucleoside phosphorylase and uridine phosphorylase genes from Klebsiella sp.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

The complete genome sequence of the gastric pathogen Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Adenine nucleoside phosphorylases in trematode Fasciola hepatica, the mammalian parasite

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

An Association between the Kinetic and Electrophoretic Properties of Human Purine‐Nucleoside‐Phosphorylase Isozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Retrovirus-mediated gene transfer in cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Pyrazolopyrimidine metabolism in parasitic protozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

An enzymatic assay of inorganic phosphate in serum using nucleoside phosphorylase and xanthine oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Gene therapy -- promises, problems and prospects

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

L-ATP is recognized by some cellular and viral enzymes: does chance drive enzymic enantioselectivity?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Pharmacokinetics and pharmacodynamics of peldesine (BCX-34), a purine nucleoside phosphorylase inhibitor, following single and multiple oral doses in healthy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

BCX-34: a novel T-cell selective immunosuppressant: purine nucleoside phosphorylase (PNP) inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Nucleotide sequence of the Escherichia coli uridine phosphorylase (udp) gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Parasite enzymes as potential targets for antiparasitic chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Stereoisomeric Selectivity of Human Deoxyribonucleoside Kinases†

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Determination of phosphate ions with an enzyme sensor system

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Cloning and expression of human uridine phosphorylase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Purification, cloning, and expression of murine uridine phosphorylase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

A continuous spectrophotometric assay for inorganic phosphate and for measuring phosphate release kinetics in biological systems

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Interaction of GTPase-activating protein with p21ras, measured using a continuous assay for inorganic phosphate release

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

A continuous visible spectrophotometric assay for aspartate transcarbamylase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Potentiating effect of (2-[2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methyl]-phenyl]ethenyl) -phosphonic acid (MDL 74,428), a potent inhibitor of purine nucleoside phosphorylase, on the antiretroviral activities of 2',3'-dideoxyinosine combined wi

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Nicotinamide riboside, an unusual, non-typical, substrate of purified purine-nucleoside phosphorylases.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Fluorescence emission properties of 8-azapurines and their nucleosides, and application to the kinetics of the reverse synthetic reaction of purine nucleoside phosphorylase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Interactions of calf spleen purine nucleoside phosphorylase with antiviral acyclic nucleoside phosphonate inhibitors: kinetics and emission studies

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

PD 141955 and CI-972: 9-deazaguanine analog purine nucleoside phosphorylase inhibitors. I. Suppression of the human mixed lymphocyte reaction (MLR).

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Human purine nucleoside phosphorylase cDNA sequence and genomic clone characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Subacute toxicity of a purine nucleoside phosphorylase inhibitor in rats

1 reference

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7 January 2021

Inhibitors of human purine nucleoside phosphorylase. Synthesis and biological activities of 8-amino-3-benzylhypoxanthine and related analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Synthesis of 1,1-difluoro-5-(1H-9-purinyl)-2-pentenylphosphonic acids and the related methano analogues. Remarkable effect of the nucleobases and the cyclopropane rings on inhibitory activity toward purine nucleoside phosphorylase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Synthesis and biological evaluation of 1,1-difluoro-2-(tetrahydro-3-furanyl)ethylphosphonic acids possessing a N9-purinylmethyl functional group at the ring. a new class of inhibitors for purine nucleoside phosphorylases

1 reference

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7 January 2021

US gene therapy in crisis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Misuse of nonlinear Scatchard plots.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Adenine as Substrate for Purine Nucleoside Phosphorylase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

Kinetics and mechanism of the acid-catalyzed hydrolysis of some purine nucleosides

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2800%2900097-8

7 January 2021

10.1016/S0163-7258(00)00097-8

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

11337031