(Q33947885)

30 July 2017

Spontaneous hepatocellular carcinoma is reduced in transgenic mice overexpressing human O6- methylguanine-DNA methyltransferase (English)

1 reference

30 July 2017

1 reference

hepatocellular carcinoma

1 reference

Z Q Zhou

1

1 reference

30 July 2017

D Manguino

2

1 reference

30 July 2017

K Kewitt

3

1 reference

30 July 2017

G W Intano

4

1 reference

30 July 2017

C A McMahan

5

1 reference

30 July 2017

D C Herbert

6

1 reference

30 July 2017

M Hanes

7

1 reference

30 July 2017

R Reddick

8

1 reference

30 July 2017

Y Ikeno

9

1 reference

30 July 2017

C A Walter

10

1 reference

30 July 2017

language of work or name

English

0 references

publication date

16 October 2001

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

1 reference

30 July 2017

98

1 reference

30 July 2017

12566-12571

1 reference

30 July 2017

22

1 reference

Inactivation of DNA mismatch repair by increased expression of yeast MLH1.

30 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Methyl-CpG-binding proteins. Targeting specific gene repression.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

DNA repair capacity: inconsistency between effect of over-expression of five NER genes and the correlation to mRNA levels in primary lymphocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage. Version 4.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Comparison of the mutagenic properties of 8-oxo-7,8-dihydro-2'-deoxyadenosine and 8-oxo-7,8-dihydro-2'-deoxyguanosine DNA lesions in mammalian cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Mutator phenotypes conferred by MLH1 overexpression and by heterozygosity for mlh1 mutations.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Reduced lung tumorigenesis in human methylguanine DNA--methyltransferase transgenic mice achieved by expression of transgene within the target cell.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Methylation of CpG dinucleotides in the lacI gene of the Big Blue transgenic mouse

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

CpG methylation, chromatin structure and gene silencing-a three-way connection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Mutation frequency declines during spermatogenesis in young mice but increases in old mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Generation of a strong mutator phenotype in yeast by imbalanced base excision repair

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Mismatch repair deficiency associated with overexpression of the MSH3 gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Epidemiological characteristics and risk factors of hepatocellular carcinoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Hypermutability and mismatch repair deficiency in RER+ tumor cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

A genetic linkage map of the mouse: current applications and future prospects

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Characterization of mutations induced by ethylnitrosourea in seminiferous tubule germ cells of transgenic B6C3F1 mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Demethylation of O6-methylguanine in a synthetic DNA polymer by an inducible activity in Escherichia coli

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Repair of alkylated DNA in Escherichia coli. Physical properties of O6-methylguanine-DNA methyltransferase.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

The role of O6-methylguanine-DNA methyltransferase in cell survival, mutagenesis and carcinogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Rapid growth of preneoplastic lesions in hepatocarcinogen-Sensitive C3H/HeJ male mice relative to C57BL/6J male mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Comparative study of diethylnitrosamine-initiated two-stage hepatocarcinogenesis in C3H, C57BL and BALB mice promoted by various hepatopromoters

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

O6-methylguanine-DNA methyltransferase activity in human liver tumors.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Quantitative analysis of genetic susceptibility to liver and lung carcinogenesis in mice.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Defective Repair Replication of DNA in Xeroderma Pigmentosum

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

Brain and liver targeted overexpression of O6-methylguanine DNA methyltransferase in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

Hepatocarcinogenesis in BXH recombinant inbred strains of mice: analysis of diverse phenotypic effects of the hepatocarcinogen sensitivity loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

Effect of target gene CpG content on spontaneous mutation in299 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

A Survey of Exact Inference for Contingency Tables

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

Immunohistochemical detection of the DNA repair enzyme O6-methylguanine-DNA methyltransferase in formalin-fixed, paraffin-embedded astrocytomas.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Chromosome mapping of murine susceptibility loci to liver carcinogenesis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=60094

Expression of yeast but not human apurinic/apyrimidinic endonuclease renders Chinese hamster cells more resistant to DNA damaging agents

29 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

The prevention of thymic lymphomas in transgenic mice by human O6-alkylguanine-DNA alkyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

Occurrence of tumors, particularly mammary tumors, in agentfree strain C3HeB mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

Genetic susceptibility to murine hepatocarcinogenesis is associated with high growth rate of NDEA-initiated hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

Rising incidence of hepatocellular carcinoma in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

Age-dependent modulation of tissue-specific repair activity for 3-methyladenine and O6-methylguanine in DNA in inbred mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

O6-alkylguanine alkyl acceptor protein activity in hepatocytes of C3H and C57BL mice during dimethylnitrosamine exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

A comparative study of the biochemical properties of human and mouse recombinant O6-methylguanine-DNA methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

CpG islands in chromatin organization and gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.221232998

Focal impairment of growth in hepatocellular neoplasms of C57BL/6 mice: a possible explanation for the strain's resistance to hepatocarcinogenesis

21 January 2018

1 reference

12 December 2020

Dose response for DNA alkylation, [3H]thymidine uptake into DNA, and O6-methylguanine-DNA methyltransferase activity in hepatocytes of rats and mice continuously exposed to dimethylnitrosamine

1 reference

12 December 2020

Targeted expression of human O(6)-methylguanine-DNA methyltransferase (MGMT) in transgenic mice protects against tumor initiation in two-stage skin carcinogenesis

1 reference

12 December 2020

Inhibition of human O6-methylguanine-DNA methyltransferase by 5-methylcytosine

1 reference

12 December 2020

Hepatocellular carcinoma

1 reference

12 December 2020

Measurement of O6-alkylguanine-DNA alkyltransferase activity in human cells and tumor tissues by restriction endonuclease inhibition

1 reference

12 December 2020

The incidence of spontaneous hepatomas in C3H, C3H (low milk factor), and CBA mice and the effect of estrogen and androgen on the occurrence of these tumors in C3H mice

1 reference

12 December 2020

Growth kinetics of microscopic hepatocellular neoplasms in carcinogen-resistant and carcinogen-responsive strains of mice

1 reference

12 December 2020

Hepatitis C and alcohol

1 reference

12 December 2020

Studies on the occurrence of spontaneous hepatomas in mice of strains C3H and CBA

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.221232998

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference