(Q33948895)

30 July 2017

The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells (English)

1 reference

30 July 2017

13

1 reference

30 July 2017

Yann-Gaël Gangloff

11

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Sébastien Viel

Sébastien Viel

5

0 references

Antoine Marçais

Antoine Marçais

1

0 references

Thierry Walzer

Thierry Walzer

14

0 references

Charlotte Viant

3

Charlotte Viant

1 reference

30 July 2017

4

Sophie Degouve

1 reference

30 July 2017

6

Aurore Fenis

1 reference

30 July 2017

Julien Cherfils-Vicini

2

1 reference

30 July 2017

Jessica Rabilloud

7

1 reference

30 July 2017

Katia Mayol

8

1 reference

30 July 2017

Armelle Tavares

9

1 reference

30 July 2017

Jacques Bienvenu

10

1 reference

30 July 2017

Eric Gilson

12

1 reference

30 July 2017

language of work or name

English

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publication date

29 June 2014

1 reference

30 July 2017

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30 July 2017

15

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30 July 2017

8

1 reference

30 July 2017

749-757

1 reference

https://scigraph.springernature.com/pub.10.1038/ni.2936

30 July 2017

0 references

cites work

Regulation of mouse NK cell development and function by cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Innate lymphoid cells--a proposal for uniform nomenclature

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

mTOR is a key modulator of ageing and age-related disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

NK cell maturation and function in C57BL/6 mice are altered by caloric restriction.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Metabolic checkpoints in activated T cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

mTOR signaling in growth control and disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

The transcription factors T-bet and Eomes control key checkpoints of natural killer cell maturation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Signal transduction during activation and inhibition of natural killer cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Cutting edge: IL-15-independent NK cell response to mouse cytomegalovirus infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Maturation of mouse NK cells is a 4-stage developmental program.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

In vivo expression of signaling proteins in reconstituted NK cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

The p110 delta of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Functions of natural killer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

The CD28 signaling pathway regulates glucose metabolism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4110708

Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor

28 July 2018

1 reference

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

21 January 2018

1 reference

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

21 January 2018

1 reference

Roles for common cytokine receptor gamma-chain-dependent cytokines in the generation, differentiation, and maturation of NK cell precursors and peripheral NK cells in vivo

21 January 2018

1 reference

Macrophage- and dendritic-cell-derived interleukin-15 receptor alpha supports homeostasis of distinct CD8+ T cell subsets

21 January 2018

1 reference

Different NK cell developmental events require different levels of IL-15 trans-presentation.

21 January 2018

1 reference

Implications for gene therapy-limiting expression of IL-2R gamma c delineate differences in signaling thresholds required for lymphocyte development and maintenance.

21 January 2018

1 reference

A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development.

21 January 2018

1 reference

Metabolic pathways in immune cell activation and quiescence

21 January 2018

1 reference

Posttranscriptional control of T cell effector function by aerobic glycolysis

21 January 2018

1 reference

Differential Responses of Immune Cells to Type I Interferon Contribute to Host Resistance to Viral Infection

21 January 2018

1 reference

Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs.

21 January 2018

1 reference

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

21 January 2018

1 reference

In vivo developmental stages in murine natural killer cell maturation.

21 January 2018

1 reference

Specific and nonspecific NK cell activation during virus infection

21 January 2018

1 reference

MAPK, phosphatidylinositol 3-kinase, and mammalian target of rapamycin pathways converge at the level of ribosomal protein S6 phosphorylation to control metabolic signaling in CD8 T cells

21 January 2018

1 reference

p110γ and p110δ Phosphoinositide 3-Kinase Signaling Pathways Synergize to Control Development and Functions of Murine NK Cells

21 January 2018

1 reference

The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion

21 January 2018

1 reference

A unifying model for mTORC1-mediated regulation of mRNA translation.

21 January 2018

1 reference

Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection

21 January 2018

1 reference

12 December 2020

CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity

1 reference

12 December 2020

IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

1 reference

12 December 2020

In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.2936

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference