(Q33952270)

English

Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cells

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cells (English)

1 reference

Europe PubMed Central

30 July 2017

multiple drug resistance

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based on heuristic

inferred from title

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based on heuristic

inferred from title

apoptotic process

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based on heuristic

inferred from title

Mikhail Blagosklonny

1

object named as

M V Blagosklonny

1 reference

Europe PubMed Central

30 July 2017

publication date

1 June 2001

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Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

15

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Europe PubMed Central

30 July 2017

936-941

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Europe PubMed Central

30 July 2017

6

1 reference

Europe PubMed Central

30 July 2017

https://scigraph.springernature.com/pub.10.1038/sj.leu.2402127

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Apoptosis as a goal of cancer therapy

1 reference

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Apoptosis in cancer therapy: crossing the threshold

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P53, cell cycle control and apoptosis: implications for cancer

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Apoptosis and cancer drug targeting

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402127

7 January 2021

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Dysregulation of apoptosis in cancer

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https://api.crossref.org/works/10.1038%2FSJ.LEU.2402127

7 January 2021

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Apoptosis in cancer

1 reference

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7 January 2021

based on heuristic

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Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402127

7 January 2021

based on heuristic

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The most unkindest cut of all: on the multiple roles of mammalian caspases

1 reference

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7 January 2021

based on heuristic

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Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis

1 reference

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Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition

1 reference

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7 January 2021

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Clinical correlates of MDR1 (P-glycoprotein) gene expression in ovarian and small-cell lung carcinomas

1 reference

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7 January 2021

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The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402127

7 January 2021

based on heuristic

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Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

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7 January 2021

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The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

1 reference

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7 January 2021

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Drug-resistance enables selective killing of resistant leukemia cells: exploiting of drug resistance instead of reversal.

1 reference

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Co-expression of several molecular mechanisms of multidrug resistance and their significance for paclitaxel cytotoxicity in human AML HL-60 cells

1 reference

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Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel.

1 reference

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7 January 2021

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Bcl-2 independence of flavopiridol-induced apoptosis. Mitochondrial depolarization in the absence of cytochrome c release.

1 reference

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7 January 2021

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A caspase inhibitor fully protects rats against lethal normothermic liver ischemia by inhibition of liver apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402127

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase inhibitors prevent cisplatin-induced apoptosis of auditory sensory cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402127

7 January 2021

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inferred from DOI database lookup

Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402127

7 January 2021

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Protection from lethal apoptosis in lipopolysaccharide-induced acute lung injury in mice by a caspase inhibitor

1 reference

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7 January 2021

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Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

1 reference

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7 January 2021

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Prevention of lymphocyte cell death in sepsis improves survival in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402127

7 January 2021

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inferred from DOI database lookup

Neuroprotection by a caspase inhibitor in acute bacterial meningitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402127

7 January 2021

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Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402127

7 January 2021

based on heuristic

inferred from DOI database lookup

Flavopiridol: the first cyclin-dependent kinase inhibitor in human clinical trials

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402127

7 January 2021

based on heuristic

inferred from DOI database lookup

Flavopiridol, a novel cyclin-dependent kinase inhibitor, in metastatic renal cancer: a University of Chicago Phase II Consortium study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402127

7 January 2021

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Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

1 reference

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7 January 2021

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Identifiers

10.1038/SJ.LEU.2402127

1 reference

Europe PubMed Central

30 July 2017

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1 reference

Europe PubMed Central

30 July 2017

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