(Q33959945)

30 July 2017

title

Synchronization in G0/G1 enhances the mitogenic response of cells overexpressing the human insulin receptor A isoform to insulin (English)

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30 July 2017

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Christine Bonnesen

1

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30 July 2017

Gitte-Mai Nelander

2

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30 July 2017

Bo Falck Hansen

3

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30 July 2017

Pia Jensen

4

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30 July 2017

Jonas S Krabbe

5

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30 July 2017

Marianne B Jensen

6

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30 July 2017

Anne Charlotte Hegelund

7

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30 July 2017

Jette E Svendsen

8

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30 July 2017

Martin B Oleksiewicz

9

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30 July 2017

publication date

8 November 2009

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Cell Biology and Toxicology

30 July 2017

published in

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30 July 2017

volume

26

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30 July 2017

issue

4

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30 July 2017

page(s)

293-307

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Creative Commons Attribution-NonCommercial 2.0 Generic

30 July 2017

copyright license

start time

8 November 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1007/s10565-009-9142-x

0 references

cites work

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Proliferation of colo-357 pancreatic carcinoma cells and survival of patients with pancreatic carcinoma are not altered by insulin glargine

28 July 2018

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New insulin analogues

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Reduced expression of the insulin receptor in mouse insulinoma (MIN6) cells reveals multiple roles of insulin signaling in gene expression, proliferation, insulin content, and secretion

28 July 2018

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28 July 2018

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The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase.

28 July 2018

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Signaling differences from the A and B isoforms of the insulin receptor (IR) in 32D cells in the presence or absence of IR substrate-1.

28 July 2018

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IRS-4 mediated mitogenic signalling by insulin and growth hormone in LB cells, a murine T-cell lymphoma devoid of IGF-I receptors

28 July 2018

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Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes

28 July 2018

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28 July 2018

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28 July 2018

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Recombinant DNA technology in the treatment of diabetes: insulin analogs

28 July 2018

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Regulation of thyroid cell proliferation by TSH and other factors: a critical evaluation of in vitro models

28 July 2018

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Differences in signaling properties of the cytoplasmic domains of the insulin receptor and insulin-like growth factor receptor in 3T3-L1 adipocytes

28 July 2018

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A function for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in fibroblasts during mitogenesis: requirement for insulin- and lysophosphatidic acid-mediated signal transduction

28 July 2018

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The long acting human insulin analog HOE 901: characteristics of insulin signalling in comparison to Asp(B10) and regular insulin

28 July 2018

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Logical analysis of timing-dependent receptor signalling specificity: application to the insulin receptor metabolic and mitogenic signalling pathways.

28 July 2018

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Growth promoting and metabolic activity of the human insulin analogue [GlyA21,ArgB31,ArgB32]insulin (HOE 901) in muscle cells

28 July 2018

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ASPB10 insulin induction of increased mitogenic responses and phenotypic changes in human breast epithelial cells: evidence for enhanced interactions with the insulin-like growth factor-I receptor

28 July 2018

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Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency

28 July 2018

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The structural basis of insulin and insulin-like growth factor-I receptor binding and negative co-operativity, and its relevance to mitogenic versus metabolic signalling.

28 July 2018

1 reference

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A transgene coding for a human insulin analog has a mitogenic effect on murine embryonic beta cells

28 July 2018

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Insulin and insulin-like growth factor-I receptors similarly stimulate deoxyribonucleic acid synthesis despite differences in cellular protein tyrosine phosphorylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Insulin as a potent, specific growth factor in a rat hepatoma cell line

28 July 2018

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Growth-stimulatory actions of insulin in vitro and in vivo

28 July 2018

1 reference

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The labile nature of the insulin signal(s) for the stimulation of DNA synthesis in mouse lens epithelial and 3T3 cells

28 July 2018

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A superactive insulin: [B10-aspartic acid]insulin(human).

28 July 2018

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The metabolic and mitogenic effects of both insulin and insulin-like growth factor are enhanced by transfection of insulin receptors into NIH3T3 fibroblasts.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Cytoplasmic domains determine signal specificity, cellular routing characteristics and influence ligand binding of epidermal growth factor and insulin receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Differential signalling potential of insulin- and IGF-1-receptor cytoplasmic domains

28 July 2018

1 reference

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Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor

28 July 2018

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Characterization of the growth of murine fibroblasts that express human insulin receptors. I. The effect of insulin in the absence of other growth factors

28 July 2018

1 reference

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Binding and biological effects of insulin, insulin analogues and insulin-like growth factors in rat aortic smooth muscle cells. Comparison of maximal growth promoting activities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Overexpression of Insulin Receptors in Fibroblast and Ovary Cells Induces a Ligand-Mediated Transformed Phenotype

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Models of insulin action on metabolic and growth response genes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Hormone responsive human breast cancer in long-term tissue culture: effect of insulin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Growth of a human breast cancer cell line in serum-free hormone-supplemented medium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Insulin glargine and receptor-mediated signalling: clinical implications in treating type 2 diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

IGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth muscle cells and fibroblasts.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Insulin-induced cell cycle progression is impaired in chinese hamster ovary cells overexpressing insulin receptor substrate-3.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Ligand-dependent autophosphorylation of the insulin receptor is positively regulated by Gi-proteins

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

The functions of insulin signaling: size isn't everything, even in Drosophila

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Insulin analogues: impact of cell model characteristics on results and conclusions regarding mitogenic properties

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Timing-dependence of insulin-receptor mitogenic versus metabolic signalling: a plausible model based on coincidence of hormone and effector binding.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Insulin receptor expression and function in human breast cancer cell lines.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896650

Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use

29 October 2018

1 reference

12 December 2020

Short-term modulation of cell proliferation and apoptosis and preventive/therapeutic efficacy of various agents in a mammary cancer model

1 reference

12 December 2020

Engineering predictability and protraction in a basal insulin analogue: the pharmacology of insulin detemir

1 reference

12 December 2020

Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin

1 reference

12 December 2020

Modifications in the B10 and B26-30 regions of the B chain of human insulin alter affinity for the human IGF-I receptor more than for the insulin receptor

1 reference

12 December 2020

Insulin signal transduction by a mutant human insulin receptor lacking the NPEY sequence. Evidence for an alternate mitogenic signaling pathway that is independent of Shc phosphorylation

1 reference

12 December 2020

Differences in the cellular processing of AspB10 human insulin compared with human insulin and LysB28ProB29 human insulin

1 reference

12 December 2020

Insulin-induced proliferation of bladder cancer cells is mediated through activation of the epidermal growth factor system

1 reference

12 December 2020

Comparison of the mitogenic potency of regular human insulin and its analogue glargine in normal and transformed human breast epithelial cells

1 reference

12 December 2020

10.1007/S10565-009-9142-X

Identifiers

DOI

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference