(Q33960093)

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Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum

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scholarly article

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Europe PubMed Central

30 July 2017

Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum (English)

1 reference

Europe PubMed Central

30 July 2017

Plasmodium falciparum

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Geert-Jan van Gemert

3

object named as

Geert-Jan van Gemert

0 references

Geert Leroux-Roels

6

object named as

Geert Leroux-Roels

0 references

object named as

Lander Foquet

2

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object named as

Anja Scholzen

8

0 references

Philip Meuleman

object named as

Philip Meuleman

5

0 references

Robert W Sauerwein

9

object named as

Robert W Sauerwein

1 reference

Europe PubMed Central

30 July 2017

Cornelus C Hermsen

7

object named as

Cornelus C Hermsen

1 reference

Europe PubMed Central

30 July 2017

4

object named as

Else M Bijker

1 reference

Europe PubMed Central

30 July 2017

1

object named as

Marije C Behet

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Europe PubMed Central

30 July 2017

publication date

5 April 2014

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Europe PubMed Central

30 July 2017

Malaria Journal

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Europe PubMed Central

30 July 2017

13

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Europe PubMed Central

30 July 2017

136

1 reference

Europe PubMed Central

30 July 2017

https://scigraph.springernature.com/pub.10.1186/1475-2875-13-136

0 references

Immunization with genetically attenuated P. falciparum parasites induces long-lived antibodies that efficiently block hepatocyte invasion by sporozoites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Model for in vivo assessment of humoral protection against malaria sporozoite challenge by passive transfer of monoclonal antibodies and immune serum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Pre-erythrocytic antibody profiles induced by controlled human malaria infections in healthy volunteers under chloroquine prophylaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Looking under the skin: the first steps in malarial infection and immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

The relationship between RTS,S vaccine-induced antibodies, CD4⁺ T cell responses and protection against Plasmodium falciparum infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Role of host cell traversal by the malaria sporozoite during liver infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Four-year efficacy of RTS,S/AS01E and its interaction with malaria exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Reduced Plasmodium berghei sporozoite liver load associates with low protective efficacy after intradermal immunization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Development of a quantitative flow cytometry-based assay to assess infection by Plasmodium falciparum sporozoites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Real-time PCR-based assay to quantify the relative amount of human and mouse tissue present in tumor xenografts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Longevity and composition of cellular immune responses following experimental Plasmodium falciparum malaria infection in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Sterile protective immunity to malaria is associated with a panel of novel P. falciparum antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

The RTS,S malaria vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Comparison of Plasmodium berghei challenge models for the evaluation of pre-erythrocytic malaria vaccines and their effect on perceived vaccine efficacy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

DEMONSTRATION OF PASSIVE IMMUNITY IN EXPERIMENTAL MONKEY MALARIA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Protection against a malaria challenge by sporozoite inoculation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Kinetics of mosquito-injected Plasmodium sporozoites in mice: fewer sporozoites are injected into sporozoite-immunized mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Acquired immunity to malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Profiling humoral immune responses to P. falciparum infection with protein microarrays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

The silent path to thousands of merozoites: the Plasmodium liver stage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Establishment of a human hepatocyte line that supports in vitro development of the exo-erythrocytic stages of the malaria parasites Plasmodium falciparum and P. vivax.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Intracellular parasite invasion strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Cell-passage activity is required for the malarial parasite to cross the liver sinusoidal cell layer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Migration through host cells activates Plasmodium sporozoites for infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Migration of Plasmodium sporozoites through cells before infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Long-term efficacy and immune responses following immunization with the RTS,S malaria vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Humoral immune responses in volunteers immunized with irradiated Plasmodium falciparum sporozoites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Circumsporozoite proteins of human malaria parasites Plasmodium falciparum and Plasmodium vivax

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Inhibition of entry of Plasmodium falciparum and P. vivax sporozoites into cultured cells; an in vitro assay of protective antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Development of sporozoite vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Humoral immunity in rodent malaria. II. Inhibition of parasitemia by serum antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Life cycle and patterns of development of Plasmodium berghei in normal and experimental hosts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Plasmodium berghei sporozoite invasion is blocked in vitro by sporozoite-immobilizing antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Gamma interferon, CD8+ T cells and antibodies required for immunity to malaria sporozoites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Malaria sporozoites leave behind trails of circumsporozoite protein during gliding motility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Infectivity of cultured Plasmodium falciparum gametocytes to mosquitoes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

The mechanisms of antibody-dependent killing mediated by lymphoid and myeloid cells are distinct based on different divalent cation requirements.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

A malaria heat-shock-like determinant expressed on the infected hepatocyte surface is the target of antibody-dependent cell-mediated cytotoxic mechanisms by nonparenchymal liver cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Activity of human volunteer sera to candidate Plasmodium falciparum circumsporozoite protein vaccines in the inhibition of sporozoite invasion assay of human hepatoma cells and hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Hepatic phase of malaria is the target of cellular mechanisms induced by the previous and the subsequent stages. A crucial role for liver nonparenchymal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Successful immunization of humans with irradiated malaria sporozoites: humoral and cellular responses of the protected individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Parasitologic and clinical human response to immunoglobulin administration in falciparum malaria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Effects of cytochalasin, phalloidin, and pH on the elongation of actin filaments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Protection against malaria by vaccination with sporozoite surface protein 2 plus CS protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Characterization of Plasmodium falciparum sporozoite surface protein 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Preliminary studies on vaccination of rhesus monkeys with irradiated sporozoites of Plasmodium knowlesi and characterization of surface antigens of these parasites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

5 July 2018

Host cell traversal is important for progression of the malaria parasite through the dermis to the liver

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

Gamma-globulin and acquired immunity to human malaria.

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

Transplacental passage of Plasmodium berghei and passive transfer of immunity in rats and mice.

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS,S Malaria Vaccine Evaluation Group

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

A phase I/IIa safety, immunogenicity, and efficacy bridging randomized study of a two-dose regimen of liquid and lyophilized formulations of the candidate malaria vaccine RTS,S/AS02A in malaria-naïve adults

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

Phase 2a trial of 0, 1, and 3 month and 0, 7, and 28 day immunization schedules of malaria vaccine RTS,S/AS02 in malaria-naïve adults at the Walter Reed Army Institute of Research

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

Recombinant Liver Stage Antigen-1 (LSA-1) formulated with AS01 or AS02 is safe, elicits high titer antibody and induces IFN-gamma/IL-2 CD4+ T cells but does not protect against experimental Plasmodium falciparum infection

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

Cultivation of fertile Plasmodium falciparum gametocytes in semi-automated systems. 1. Static cultures

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

Molecular detection and quantification of Plasmodium falciparum-infected human hepatocytes in chimeric immune-deficient mice

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

Detection of Plasmodium falciparum malaria parasites in vivo by real-time quantitative PCR.

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

Intravital microscopy demonstrating antibody-mediated immobilisation of Plasmodium berghei sporozoites injected into skin by mosquitoes

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

Assessment of antibody protection against malaria sporozoites must be done by mosquito injection of sporozoites

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

Dissecting in vitro host cell infection by Plasmodium sporozoites using flow cytometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

29 October 2018

Safety and immunogenicity of rts,s+trap malaria vaccine, formulated in the as02a adjuvant system, in infant rhesus monkeys.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113136

29 October 2018

Expression of thrombospondin-related anonymous protein in Plasmodium falciparum sporozoites

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

Complete in vitro maturation of Plasmodium falciparum gametocytes

1 reference

https://api.crossref.org/works/10.1186%2F1475-2875-13-136

21 January 2018

Functional status of cells from lymphoid and myeloid tissues in mice with severe combined immunodeficiency disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24708526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synchronization of Plasmodium falciparum gametocytes using an automated suspension culture system

1 reference

https://pubmed.ncbi.nlm.nih.gov/24708526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural killer (NK) cells are present in mice with severe combined immunodeficiency (scid)

1 reference

https://pubmed.ncbi.nlm.nih.gov/24708526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1475-2875-13-136

1 reference

Europe PubMed Central

30 July 2017

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1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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