(Q33960795)

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A cyclopalladated complex interacts with mitochondrial membrane thiol-groups and induces the apoptotic intrinsic pathway in murine and cisplatin-resistant human tumor cells.

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scholarly article

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7 February 2020

A cyclopalladated complex interacts with mitochondrial membrane thiol-groups and induces the apoptotic intrinsic pathway in murine and cisplatin-resistant human tumor cells (English)

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7 February 2020

apoptotic process

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Edson Lucas dos Santos

11

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7 February 2020

author name string

Fabiana A Serrano

1

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7 February 2020

Alisson L Matsuo

2

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7 February 2020

Priscila T Monteforte

3

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7 February 2020

Alexandre Bechara

4

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7 February 2020

Soraya S Smaili

5

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7 February 2020

Débora P Santana

6

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7 February 2020

Tiago Rodrigues

7

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7 February 2020

Felipe V Pereira

8

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7 February 2020

Luis S Silva

9

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7 February 2020

Joel Machado

10

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7 February 2020

João B Pesquero

12

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7 February 2020

Rafael M Martins

13

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7 February 2020

Luiz R Travassos

14

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7 February 2020

Antonio C F Caires

15

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7 February 2020

Elaine G Rodrigues

16

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7 February 2020

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14 July 2011

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7 February 2020

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7 February 2020

11

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7 February 2020

296

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7 February 2020

copyright license

Creative Commons Attribution 2.0 Generic

14 July 2011

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April 2022 Public Data File from Crossref

copyright status

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April 2022 Public Data File from Crossref

https://scigraph.springernature.com/pub.10.1186/1471-2407-11-296

0 references

Antimycobacterial and antitumor activities of palladium(II) complexes containing isonicotinamide (isn): X-ray structure of trans-[Pd(N3)2(isn)(2)].

1 reference

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5 July 2018

Synthesis of chiral β-aminoalcohol palladium complexes exhibiting cytotoxic properties

1 reference

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5 July 2018

Evaluation of in vitro cytotoxicity and hepatotoxicity of platinum(II) and palladium(II) oxalato complexes with adenine derivatives as carrier ligands.

1 reference

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5 July 2018

Targeting mitochondria for cancer therapy

1 reference

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5 July 2018

Mechanisms of tumor cell necrosis.

1 reference

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5 July 2018

The mechanism of action of platinum anticancer agents--what do we really know about it?

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5 July 2018

Systemic therapy for cutaneous melanoma

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5 July 2018

Calcium and cell death signaling in neurodegeneration and aging

1 reference

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5 July 2018

Mitochondrial gateways to cancer

1 reference

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5 July 2018

Gene Therapy against Murine Melanoma B16F10-Nex2 Using IL-13Ralpha2-Fc Chimera and Interleukin 12 in Association with a Cyclopalladated Drug

1 reference

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5 July 2018

Palladacycles catalyse the oxidation of critical thiols of the mitochondrial membrane proteins and lead to mitochondrial permeabilization and cytochrome c release associated with apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156809

5 July 2018

The role of cellular accumulation in determining sensitivity to platinum-based chemotherapy

1 reference

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5 July 2018

Recent advances involving palladium (II) complexes for the cancer therapy

1 reference

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5 July 2018

Mitochondria as a critical target of the chemotheraputic agent cisplatin in head and neck cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156809

5 July 2018

Mitochondrial membrane permeabilization in cell death

1 reference

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5 July 2018

Chemical genetic approaches to probing cell death

1 reference

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5 July 2018

Cell death by necrosis: towards a molecular definition

1 reference

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5 July 2018

Treatment of metastatic malignant melanoma

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5 July 2018

Mitochondrial permeability transitions: how many doors to the house?

1 reference

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5 July 2018

Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156809

5 July 2018

Melanoma heterogeneity: differential, invasive, metastatic properties and profiles of cathepsin B, D and L activities in subclones of the B16F10-NEX2 cell line.

1 reference

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5 July 2018

Cyclopalladated compounds as chemotherapeutic agents: Antitumor activity against a murine melanoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156809

5 July 2018

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

1 reference

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5 July 2018

Mitochondria, calcium and pro-apoptotic proteins as mediators in cell death signaling

1 reference

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5 July 2018

Mitochondria in myelinating cells: calcium signaling in oligodendrocyte precursor cells

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5 July 2018

The mitochondrial permeability transition pore and its role in cell death

1 reference

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5 July 2018

Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

1 reference

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5 July 2018

The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins

1 reference

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5 July 2018

Movement of Bax from the cytosol to mitochondria during apoptosis

1 reference

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5 July 2018

Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase

1 reference

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5 July 2018

Mitochondrial permeability transition triggers lymphocyte apoptosis.

1 reference

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5 July 2018

Analysis of two cycloplatinated compounds derived from N-(4-methoxyphenyl)-alpha-benzoylbenzylidenamine. Comparison of the activity of these compounds with other isostructural cyclopalladated compounds.

1 reference

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1 reference

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1 reference

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1 reference

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Advances in platinum chemotherapeutics

1 reference

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Synthesis and cytotoxicity of some cyclometallated palladium complexes.

1 reference

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1 reference

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21 January 2018

Mitochondrial alterations and apoptosis in smooth muscle from aged rats

1 reference

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21 January 2018

Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-296

21 January 2018

Bcl-2 prevents loss of mitochondria in CCCP-induced apoptosis

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-296

21 January 2018

Bax affects intracellular Ca2+ stores and induces Ca2+ wave propagation

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-296

21 January 2018

Necroptosis: a specialized pathway of programmed necrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21756336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane protein thiol cross-linking associated with the permeabilization of the inner mitochondrial membrane by Ca2+ plus prooxidants

1 reference

https://pubmed.ncbi.nlm.nih.gov/21756336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics and mechanism of uptake of platinum-based pharmaceuticals by the rat small intestine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21756336

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2407-11-296

1 reference

Europe PubMed Central

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7 February 2020

Dimensions Publication ID

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https://scigraph.springernature.com/pub.10.1186/1471-2407-11-296

9 September 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21756336%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

Europe PubMed Central

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7 February 2020

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