(Q33964282)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

TPL2 mediates autoimmune inflammation through activation of the TAK1 axis of IL-17 signaling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

0 references

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

author name string

Yichuan Xiao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Jin Jin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Mikyoung Chang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Mako Nakaya

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Hongbo Hu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Xiaofei Zhou

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

George C Brittain

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Xuhong Cheng

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Shao-Cong Sun

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

language of work or name

English

0 references

publication date

30 June 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

21 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

volume

211

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

page(s)

1689-1702

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

Modeling the heterogeneity of multiple sclerosis in animals

21 March 2020

cites work

1 reference

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Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation

5 July 2018

1 reference

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The activation and regulation of IL-17 receptor mediated signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

IκB kinase 2 regulates TPL-2 activation of extracellular signal-regulated kinases 1 and 2 by direct phosphorylation of TPL-2 serine 400

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

NEMO ensures signaling specificity of the pleiotropic IKKβ by directing its kinase activity toward IκBα.

5 July 2018

1 reference

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Tpl2 ablation promotes intestinal inflammation and tumorigenesis in Apcmin mice by inhibiting IL-10 secretion and regulatory T-cell generation.

5 July 2018

1 reference

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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

5 July 2018

1 reference

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Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)

5 July 2018

1 reference

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The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation

5 July 2018

1 reference

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Neuroprotection mediated through estrogen receptor-alpha in astrocytes

5 July 2018

1 reference

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IL-17 receptor signaling and T helper 17-mediated autoimmune demyelinating disease

5 July 2018

1 reference

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Tpl2 kinase signal transduction in inflammation and cancer.

5 July 2018

1 reference

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Functional specialization of interleukin-17 family members

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis

5 July 2018

1 reference

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Act1, a U-box E3 ubiquitin ligase for IL-17 signaling.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

Structure and signalling in the IL-17 receptor family

5 July 2018

1 reference

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Autoimmune T cell responses in the central nervous system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

5 July 2018

1 reference

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Deregulated activation of oncoprotein kinase Tpl2/Cot in HTLV-I-transformed T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

Regulation of T cell development by the deubiquitinating enzyme CYLD

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IkappaB kinase-induced proteolysis of NF-kappaB1 p105.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

A serine/threonine kinase, Cot/Tpl2, modulates bacterial DNA-induced IL-12 production and Th cell differentiation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology

5 July 2018

1 reference

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IkappaB kinase is an essential component of the Tpl2 signaling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

NF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

The STIR-domain superfamily in signal transduction, development and immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

Requirement of tumor necrosis factor receptor-associated factor (TRAF)6 in interleukin 17 signal transduction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4113941

Act1 adaptor protein is an immediate and essential signaling component of interleukin-17 receptor

5 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20132640

GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20132640

The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20132640

Essential function for the kinase TAK1 in innate and adaptive immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20132640

Upregulation of IL-17, but not of IL-9, in circulating cells of CIS and relapsing MS patients. Impact of corticosteroid therapy on the cytokine network

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24980047

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24980047

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20132640

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

24980047

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24980047%20AND%20SRC:MED&resulttype=core&format=json