(Q33967269)

English

The selenium-independent inherent pro-oxidant NADPH oxidase activity of mammalian thioredoxin reductase and its selenium-dependent direct peroxidase activities

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

The selenium-independent inherent pro-oxidant NADPH oxidase activity of mammalian thioredoxin reductase and its selenium-dependent direct peroxidase activities (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

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inferred from title

author name string

Qing Cheng

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

William E Antholine

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Judith M Myers

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Balaraman Kalyanaraman

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Elias S J Arnér

5

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Charles R Myers

6

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

0 references

publication date

10 May 2010

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

285

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

28

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

21708-21723

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy

1 reference

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5 July 2018

The effects of hexavalent chromium on thioredoxin reductase and peroxiredoxins in human bronchial epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

No selenium required: reactions catalyzed by mammalian thioredoxin reductase that are independent of a selenocysteine residue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Focus on mammalian thioredoxin reductases--important selenoproteins with versatile functions

1 reference

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5 July 2018

Highly active dimeric and low-activity tetrameric forms of selenium-containing rat thioredoxin reductase 1

1 reference

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5 July 2018

The effects of acrolein on peroxiredoxins, thioredoxins, and thioredoxin reductase in human bronchial epithelial cells

1 reference

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5 July 2018

Crystal structure and catalysis of the selenoprotein thioredoxin reductase 1

1 reference

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5 July 2018

1 reference

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5 July 2018

Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells

1 reference

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5 July 2018

Hexavalent chromium causes the oxidation of thioredoxin in human bronchial epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Thioredoxin reductase-1 knock down does not result in thioredoxin-1 oxidation

1 reference

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5 July 2018

Acrolein oxidizes the cytosolic and mitochondrial thioredoxins in human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Detection, characterization, and decay kinetics of ROS and thiyl adducts of mito-DEPMPO spin trap

1 reference

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5 July 2018

Reduction of hexavalent chromium by human cytochrome b5: generation of hydroxyl radical and superoxide

1 reference

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5 July 2018

On the potential of thioredoxin reductase inhibitors for cancer therapy

1 reference

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5 July 2018

Motexafin gadolinium, a tumor-selective drug targeting thioredoxin reductase and ribonucleotide reductase

1 reference

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5 July 2018

Synthesis of 5-nitro-2-furancarbohydrazides and their cis-diamminedichloroplatinum complexes as bitopic and irreversible human thioredoxin reductase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity

1 reference

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5 July 2018

Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Assessment of production conditions for efficient use of Escherichia coli in high-yield heterologous recombinant selenoprotein synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Detection of reactive oxygen and nitrogen species by EPR spin trapping

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

The thioredoxin system—From science to clinic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Spin traps: in vitro toxicity and stability of radical adducts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Rapid induction of cell death by selenium-compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocysteine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Recombinant expression of mammalian selenocysteine-containing thioredoxin reductase and other selenoproteins in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Reactive oxygen species, antioxidants, and the mammalian thioredoxin system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Physiological functions of thioredoxin and thioredoxin reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Structure and mechanism of mammalian thioredoxin reductase: the active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Effect of redox-active drugs on superoxide generation from nitric oxide synthases: biological and toxicological implications

1 reference

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5 July 2018

High-level expression in Escherichia coli of selenocysteine-containing rat thioredoxin reductase utilizing gene fusions with engineered bacterial-type SECIS elements and co-expression with the selA, selB and selC genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Iron stimulates the rate of reduction of hexavalent chromium by human microsomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Chromate-mediated free radical generation from cysteine, penicillamine, hydrogen peroxide, and lipid hydroperoxides.

1 reference

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5 July 2018

Reaction of Cr(VI) with ascorbate and hydrogen peroxide generates hydroxyl radicals and causes DNA damage: role of a Cr(IV)-mediated Fenton-like reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Oxygen toxicity, oxygen radicals, transition metals and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898413

5 July 2018

Production of hydroxyl radical by decomposition of superoxide spin-trapped adducts

1 reference

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5 July 2018

Detection of superoxide generated by endothelial cells

1 reference

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5 July 2018

Protection against tissue damage in vivo by desferrioxamine: what is its mechanism of action?

1 reference

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5 July 2018

ESR spin trapping detection of hydroxyl radicals in the reactions of Cr(V) complexes with hydrogen peroxide

1 reference

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5 July 2018

On the hydroxyl radical formation in the reaction between hydrogen peroxide and biologically generated chromium(V) species

1 reference

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5 July 2018

Spin trapping evidence for the lack of significant hydroxyl radical production during the respiration burst of human phagocytes using a spin adduct resistant to superoxide-mediated destruction.

1 reference

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5 July 2018

Selenite is a substrate for calf thymus thioredoxin reductase and thioredoxin and elicits a large non-stoichiometric oxidation of NADPH in the presence of oxygen

1 reference

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5 July 2018

Deferoxamine inhibition of Cr(V)-mediated radical generation and deoxyguanine hydroxylation: ESR and HPLC evidence

1 reference

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5 July 2018

Bovine thioredoxin system. Purification of thioredoxin reductase from calf liver and thymus and studies of its function in disulfide reduction

1 reference

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5 July 2018

Inhibition of thioredoxin reductase but not of glutathione reductase by the major classes of alkylating and platinum-containing anticancer compounds.

1 reference

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21 January 2018

Analysis of the inhibition of mammalian thioredoxin, thioredoxin reductase, and glutaredoxin by cis-diamminedichloroplatinum (II) and its major metabolite, the glutathione-platinum complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.117259

21 January 2018

Interactions of quinones with thioredoxin reductase: a challenge to the antioxidant role of the mammalian selenoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.117259

21 January 2018

Tagging recombinant proteins with a Sel-tag for purification, labeling with electrophilic compounds or radiolabeling with 11C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.117259

21 January 2018

Exploiting the 21st amino acid-purifying and labeling proteins by selenolate targeting.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.117259

21 January 2018

Titration and conditional knockdown of the prfB gene in Escherichia coli: effects on growth and overproduction of the recombinant mammalian selenoprotein thioredoxin reductase.

1 reference

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21 January 2018

Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds

1 reference

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21 January 2018

Simulation of multiple isotropic spin-trap EPR spectra.

1 reference

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21 January 2018

Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.117259

21 January 2018

Synthesis and biochemical applications of a solid cyclic nitrone spin trap: a relatively superior trap for detecting superoxide anions and glutathiyl radicals

1 reference

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21 January 2018

Design of New Derivatives of Nitrone DEPMPO Functionalized at C-4 for Further Specific Applications in Superoxide Radical Detection

1 reference

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21 January 2018

5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline N-oxide: a new efficient phosphorylated nitrone for the in vitro and in vivo spin trapping of oxygen-centered radicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/20457604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1-Chloro-2,4-dinitrobenzene is an irreversible inhibitor of human thioredoxin reductase. Loss of thioredoxin disulfide reductase activity is accompanied by a large increase in NADPH oxidase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20457604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocystine strongly stimulates the reaction via catalytically generated selenols

1 reference

https://pubmed.ncbi.nlm.nih.gov/20457604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of sulfur-centered radical intermediates formed during the oxidation of thiols and sulfite by peroxynitrite. ESR-spin trapping and oxygen uptake studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20457604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of mitochondrial thioredoxin reductase and its involvement in the redox regulation of membrane permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/20457604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian thioredoxin reductase is irreversibly inhibited by dinitrohalobenzenes by alkylation of both the redox active selenocysteine and its neighboring cysteine residue

1 reference

https://pubmed.ncbi.nlm.nih.gov/20457604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Function of thioredoxin reductase as a peroxynitrite reductase using selenocystine or ebselen

1 reference

https://pubmed.ncbi.nlm.nih.gov/20457604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diastereoselective synthesis and ESR study of 4-phenylDEPMPO spin traps

1 reference

https://pubmed.ncbi.nlm.nih.gov/20457604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties and biological activities of thioredoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20457604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A determination of antioxidant efficiencies using ESR and computational methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/20457604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ESR spin-trapping studies on the reaction of Fe2+ ions with H2O2-reactive species in oxygen toxicity in biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/20457604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spin trapping study on the kinetics of Fe2+ autoxidation: Formation of spin adducts and their destruction by superoxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20457604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of O2.- in the production of HO.: in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20457604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.117259

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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