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A C-terminal region of RAG1 contacts the coding DNA during V(D)J recombination.
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86807
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5 November 2019
title
A C-terminal region of RAG1 contacts the coding DNA during V(D)J recombination
(English)
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86807
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5 November 2019
author
Moshe Sadofsky
series ordinal
3
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86807
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11238939%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
author name string
X Mo
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1
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Europe PubMed Central
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86807
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5 November 2019
T Bailin
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2
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86807
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11238939%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
language of work or name
English
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publication date
1 March 2001
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86807
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5 November 2019
published in
Molecular and Cellular Biology
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Europe PubMed Central
PMC publication ID
86807
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11238939%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
volume
21
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Europe PubMed Central
PMC publication ID
86807
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11238939%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
issue
6
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Europe PubMed Central
PMC publication ID
86807
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11238939%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
page(s)
2038-2047
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86807
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11238939%20AND%20SRC:MED&resulttype=core&format=json
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5 November 2019
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5 July 2018
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A highly ordered structure in V(D)J recombination cleavage complexes is facilitated by HMG1.
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5 July 2018
Mutations of acidic residues in RAG1 define the active site of the V(D)J recombinase
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5 July 2018
Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination
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Mechanistic basis for coding end sequence effects in the initiation of V(D)J recombination
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5 July 2018
The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2
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5 July 2018
Signal joint formation is inhibited in murine scid preB cells and fibroblasts in substrates with homopolymeric coding ends.
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5 July 2018
A RAG1 and RAG2 tetramer complex is active in cleavage in V(D)J recombination
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5 July 2018
DNA hairpin opening mediated by the RAG1 and RAG2 proteins
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5 July 2018
Detection of RAG protein-V(D)J recombination signal interactions near the site of DNA cleavage by UV cross-linking
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5 July 2018
RAG-2 promotes heptamer occupancy by RAG-1 in the assembly of a V(D)J initiation complex
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5 July 2018
RAG1 and RAG2 cooperate in specific binding to the recombination signal sequence in vitro
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5 July 2018
Hairpin coding end opening is mediated by RAG1 and RAG2 proteins
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PubMed Central
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5 July 2018
The RAG-HMG1 complex enforces the 12/23 rule of V(D)J recombination specifically at the double-hairpin formation step
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PubMed Central
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5 July 2018
V(D)J recombination signal recognition: distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2.
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5 July 2018
Functional analysis of coordinated cleavage in V(D)J recombination
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5 July 2018
Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences
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5 July 2018
Spatial organization of transcription elongation complex in Escherichia coli
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5 July 2018
Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination
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5 July 2018
The composition of coding joints formed in V(D)J recombination is strongly affected by the nucleotide sequence of the coding ends and their relationship to the recombination signal sequences
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PubMed Central
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5 July 2018
Nucleotide deletion and P addition in V(D)J recombination: a determinant role of the coding-end sequence
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PubMed Central
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5 July 2018
Stimulation of V(D)J cleavage by high mobility group proteins
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5 July 2018
V(D)J recombination: modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins
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5 July 2018
Recent advances in understanding V(D)J recombination.
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5 July 2018
RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination
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5 July 2018
DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences
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5 July 2018
Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage
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5 July 2018
The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination
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PubMed Central
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5 July 2018
Initiation of V(D)J recombination in vitro obeying the 12/23 rule
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86807
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5 July 2018
Mechanistic constraints on diversity in human V(D)J recombination
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86807
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5 July 2018
Coding end sequence can markedly affect the initiation of V(D)J recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86807
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5 July 2018
Expression and V(D)J recombination activity of mutated RAG-1 proteins
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5 July 2018
The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses
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5 July 2018
Initiation of V(D)J recombination in a cell-free system.
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5 July 2018
Photocrosslinking of 5-Iodouracil-Substituted RNA and DNA to Proteins
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5 July 2018
Somatic generation of antibody diversity
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5 July 2018
The V(D)J recombination activating gene, RAG-1.
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5 July 2018
RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
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5 July 2018
Cutting and closing without recombination in V(D)J joining
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5 July 2018
Mapping the active site of ribonuclease P RNA using a substrate containing a photoaffinity agent.
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5 July 2018
The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination
1 reference
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29 October 2018
Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps
1 reference
stated in
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86807
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29 October 2018
RAG-1 mutations that affect the target specificity of V(D)j recombination: a possible direct role of RAG-1 in site recognition.
1 reference
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29 October 2018
Mapping protease susceptibility sites on the Escherichia coli transcription factor sigma70
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11238939
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cell-free V(D)J recombination
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11238939
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Novel strand exchanges in V(D)J recombination
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11238939
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Studies of the functional topography of Escherichia coli RNA polymerase. A method for localization of the sites of affinity labelling
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11238939
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.21.6.2038-2047.2001
1 reference
stated in
Europe PubMed Central
PMC publication ID
86807
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11238939%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
PMC publication ID
86807
1 reference
stated in
Europe PubMed Central
PMC publication ID
86807
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11238939%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
PubMed publication ID
11238939
1 reference
stated in
Europe PubMed Central
PMC publication ID
86807
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11238939%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 November 2019
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