(Q33972763)

English

Insulin Augmentation of 17α-Hydroxylase Activity Is Mediated by Phosphatidyl Inositol 3-Kinase But Not Extracellular Signal-Regulated Kinase-1/2 in Human Ovarian Theca Cells

scientific article published on September 25, 2003

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Insulin augmentation of 17alpha-hydroxylase activity is mediated by phosphatidyl inositol 3-kinase but not extracellular signal-regulated kinase-1/2 in human ovarian theca cells (English)

1 reference

Europe PubMed Central

30 July 2017

Insulin Augmentation of 17α-Hydroxylase Activity Is Mediated by Phosphatidyl Inositol 3-Kinase But Not Extracellular Signal-Regulated Kinase-1/2 in Human Ovarian Theca Cells (English)

1 reference

10.1210/EN.2003-0329

https://api.crossref.org/works/10.1210/EN.2003-0329

14 March 2024

1 reference

based on heuristic

inferred from title

1 reference

10.1210/EN.2003-0329

https://api.crossref.org/works/10.1210/EN.2003-0329

14 March 2024

author name string

Iqbal Munir

1

1 reference

Europe PubMed Central

30 July 2017

Hui-Wen Yen

2

1 reference

Europe PubMed Central

30 July 2017

Donna Torbati

4

1 reference

Europe PubMed Central

30 July 2017

David H. Geller

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14512432

14 March 2024

Rebecca M. Bierden

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14512432

14 March 2024

Stacy R. Weitsman

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14512432

14 March 2024

Sanjay K. Agarwal

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14512432

14 March 2024

Denis A. Magoffin

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14512432

14 March 2024

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publication date

25 September 2003

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Europe PubMed Central

30 July 2017

number of pages

9

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inferred from page(s)

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Europe PubMed Central

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145

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30 July 2017

1

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Europe PubMed Central

30 July 2017

175-183

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Europe PubMed Central

30 July 2017

The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis

1 reference

30 December 2023

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The prevalence of polycystic ovaries in women with type 2 diabetes mellitus.

2

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10.1210/EN.2003-0329

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Can metformin reduce insulin resistance in polycystic ovary syndrome?

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The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome.

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Metformin treatment reduces ovarian cytochrome P-450c17alpha response to human chorionic gonadotrophin in women with insulin resistance-related polycystic ovary syndrome.

9

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Thiazolidinediones in the treatment of insulin resistance and type II diabetes

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Effect of troglitazone on endocrine and ovulatory performance in women with insulin resistance-related polycystic ovary syndrome.

11

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Molecular scanning of the insulin receptor gene in women with polycystic ovarian syndrome.

12

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Lack of insulin resistance in fibroblasts from subjects with polycystic ovary syndrome

14

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Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle. A potential mechanism for insulin resistance in the polycystic ovary syndrome

15

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Defects in insulin receptor signaling in vivo in the polycystic ovary syndrome (PCOS).

16

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Regulation of androgen production in cultured human thecal cells by insulin-like growth factor I and insulin.

19

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Metabolic regulation of androgen production by human thecal cells in vitro

20

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Identification of common ligand binding determinants of the insulin and insulin-like growth factor 1 receptors. Insights into mechanisms of ligand binding

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Monoclonal antibodies to the human insulin receptor block insulin binding and inhibit insulin action

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Interaction of the monoclonal antibodies alpha IR-1 and alpha IR-3 with insulin and somatomedin-C receptors

24

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A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

25

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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Identification of a novel inhibitor of mitogen-activated protein kinase kinase

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10.1210/EN.2003-0329

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Insulin action in the normal and polycystic ovary

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Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting

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Identification of a monoclonal antibody which can distinguish between two distinct species of the type I receptor for insulin-like growth factor

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Evidence for distinctive and intrinsic defects in insulin action in polycystic ovary syndrome

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Signaling pathways in insulin action: molecular targets of insulin resistance

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Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

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Insulin suppresses transactivation by CAAT/enhancer-binding proteins beta (C/EBPbeta). Signaling to p300/CREB-binding protein by protein kinase B disrupts interaction with the major activation domain of C/EBPbeta

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Protein kinase C-zeta regulates transcription of the matrix metalloproteinase-9 gene induced by IL-1 and TNF-alpha in glioma cells via NF-kappa B

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Signal transduction pathways that regulate eukaryotic protein synthesis

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CAMP-dependent protein kinase enhances CYP17 transcription via MKP-1 activation in H295R human adrenocortical cells

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Thiazolidinediones but not metformin directly inhibit the steroidogenic enzymes P450c17 and 3beta -hydroxysteroid dehydrogenase

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Identifiers

10.1210/EN.2003-0329

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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