(Q33975871)

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Genome-wide analysis of Saccharomyces cerevisiae identifies cellular processes affecting intracellular aggregation of Alzheimer's amyloid-β42: importance of lipid homeostasis

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Genome-wide analysis of Saccharomyces cerevisiae identifies cellular processes affecting intracellular aggregation of Alzheimer's amyloid-β42: importance of lipid homeostasis (English)

1 reference

Europe PubMed Central

30 July 2017

Alzheimer's disease

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Saccharomyces cerevisiae

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based on heuristic

inferred from title

author name string

S Nair

1

1 reference

Europe PubMed Central

30 July 2017

M Traini

2

1 reference

Europe PubMed Central

30 July 2017

I W Dawes

3

1 reference

Europe PubMed Central

30 July 2017

G G Perrone

4

1 reference

Europe PubMed Central

30 July 2017

publication date

28 May 2014

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Europe PubMed Central

30 July 2017

Molecular Biology of the Cell

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Europe PubMed Central

30 July 2017

25

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Europe PubMed Central

30 July 2017

15

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Europe PubMed Central

30 July 2017

2235-2249

1 reference

Europe PubMed Central

30 July 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4116298/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Combination therapy in a transgenic model of Alzheimer's disease

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

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5 July 2018

Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model.

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5 July 2018

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

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5 July 2018

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5 July 2018

Biochemical and genetic analysis of the yeast proteome with a movable ORF collection

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5 July 2018

Amyloid peptide attenuates the proteasome activity in neuronal cells

1 reference

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5 July 2018

Sequence determinants of enhanced amyloidogenicity of Alzheimer A{beta}42 peptide relative to A{beta}40.

1 reference

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5 July 2018

Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease

1 reference

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5 July 2018

The alpha-ketoglutarate-dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration

1 reference

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5 July 2018

A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease

1 reference

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5 July 2018

Genome-wide analysis reveals inositol, not choline, as the major effector of Ino2p-Ino4p and unfolded protein response target gene expression in yeast

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5 July 2018

Subcellular topography of neuronal Abeta peptide in APPxPS1 transgenic mice

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5 July 2018

Insertion of Alzheimer's A beta 40 peptide into lipid monolayers

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5 July 2018

Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein

1 reference

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5 July 2018

The function of cytidine coenzymes in the biosynthesis of phospholipides

1 reference

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5 July 2018

Role of the yeast VAP homolog, Scs2p, in INO1 expression and phospholipid metabolism

1 reference

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5 July 2018

A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP

1 reference

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5 July 2018

Global transcription analysis of Krebs tricarboxylic acid cycle mutants reveals an alternating pattern of gene expression and effects on hypoxic and oxidative genes

1 reference

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5 July 2018

Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

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5 July 2018

Functional profiling of the Saccharomyces cerevisiae genome

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5 July 2018

Mutations that reduce aggregation of the Alzheimer's Abeta42 peptide: an unbiased search for the sequence determinants of Abeta amyloidogenesis

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5 July 2018

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5 July 2018

Functional organization of the yeast proteome by systematic analysis of protein complexes

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5 July 2018

Genome-wide responses to mitochondrial dysfunction

1 reference

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5 July 2018

The alpha-ketoglutarate dehydrogenase complex in neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116298

5 July 2018

Intraneuronal Abeta42 accumulation in human brain.

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5 July 2018

Amyloid beta peptide membrane perturbation is the basis for its biological effects

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5 July 2018

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

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5 July 2018

The role of A beta 42 in Alzheimer's disease

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5 July 2018

The Saccharomyces cerevisiae SCS2 gene product, a homolog of a synaptobrevin-associated protein, is an integral membrane protein of the endoplasmic reticulum and is required for inositol metabolism

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5 July 2018

The toxicity of the Alzheimer's beta-amyloid peptide correlates with a distinct fiber morphology.

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5 July 2018

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

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5 July 2018

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

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5 July 2018

INO2 and INO4 gene products, positive regulators of phospholipid biosynthesis in Saccharomyces cerevisiae, form a complex that binds to the INO1 promoter

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5 July 2018

Aggregation state and neurotoxic properties of Alzheimer beta-amyloid peptide

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5 July 2018

Regulatory mutations of inositol biosynthesis in yeast: isolation of inositol-excreting mutants

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5 July 2018

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5 July 2018

The INO2 and INO4 loci of Saccharomyces cerevisiae are pleiotropic regulatory genes

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5 July 2018

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

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5 July 2018

Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria

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5 July 2018

Amyloid plaque core protein in Alzheimer disease and Down syndrome

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5 July 2018

Saccharomyces cerevisiae cho2 mutants are deficient in phospholipid methylation and cross-pathway regulation of inositol synthesis.

1 reference

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5 July 2018

The membrane-associated enzyme phosphatidylserine synthase is regulated at the level of mRNA abundance

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5 July 2018

Expression of the Saccharomyces cerevisiae inositol-1-phosphate synthase (INO1) gene is regulated by factors that affect phospholipid synthesis

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5 July 2018

Regulation of CDP-diacylglycerol synthase activity in Saccharomyces cerevisiae

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5 July 2018

Mutations in the Saccharomyces cerevisiae opi3 gene: effects on phospholipid methylation, growth and cross-pathway regulation of inositol synthesis.

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5 July 2018

Yeast phosphatidylethanolamine methylation pathway. Cloning and characterization of two distinct methyltransferase genes.

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5 July 2018

PET genes of Saccharomyces cerevisiae

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5 July 2018

Amyloid Protein and Alzheimer's Disease

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5 July 2018

Alzheimer's disease: the amyloid cascade hypothesis

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5 July 2018

Evidence for a membrane defect in Alzheimer disease brain

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5 July 2018

Beta-amyloid accumulation impairs multivesicular body sorting by inhibiting the ubiquitin-proteasome system.

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21 January 2018

Mitochondrial abnormalities in Alzheimer brain: mechanistic implications

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21 January 2018

Alzheimer's Abeta fused to green fluorescent protein induces growth stress and a heat shock response.

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21 January 2018

Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease.

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21 January 2018

Lipid membrane templates the ordering and induces the fibrillogenesis of Alzheimer's disease amyloid-beta peptide

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21 January 2018

Templating effect of lipid membranes on Alzheimer's amyloid beta peptide.

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21 January 2018

Heat shock prevents alpha-synuclein-induced apoptosis in a yeast model of Parkinson's disease

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21 January 2018

Identification of molecular compounds critical to Alzheimer's-like plaque formation.

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21 January 2018

From brain to food: analysis of phosphatidylcholins, lyso-phosphatidylcholins and phosphatidylcholin-plasmalogens derivates in Alzheimer's disease human post mortem brains and mice model via mass spectrometry.

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21 January 2018

Effect of an amyloidogenic sequence attached to yellow fluorescent protein.

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21 January 2018

Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: Abeta dimers and trimers correlate with neurotoxicity

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21 January 2018

Mitochondrial dysfunction enhances Gal4-dependent transcription

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21 January 2018

Selective loss of KGDHC-enriched neurons in Alzheimer temporal cortex: does mitochondrial variation contribute to selective vulnerability?

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21 January 2018

Involvement of cell surface glycosyl-phosphatidylinositol-linked aspartyl proteases in alpha-secretase-type cleavage and ectodomain solubilization of human Alzheimer beta-amyloid precursor protein in yeast.

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21 January 2018

Amyloid plaques and amyloid-beta oligomers: an ongoing debate.

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21 January 2018

Adsorption of amyloid beta (1-40) peptide to phosphatidylethanolamine monolayers

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21 January 2018

Inositol stereoisomers stabilize an oligomeric aggregate of Alzheimer amyloid beta peptide and inhibit abeta -induced toxicity.

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21 January 2018

Yeast cells provide insight into alpha-synuclein biology and pathobiology

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21 January 2018

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21 January 2018

Antichaos and Adaptation

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21 January 2018

A metabolic link between S-adenosylhomocysteine and polyunsaturated fatty acid metabolism in Alzheimer's disease.

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21 January 2018

Alteration of myo-inositol monophosphatase in Alzheimer's disease brains.

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21 January 2018

Interorganellar communication. Altered nuclear gene expression profiles in a yeast mitochondrial dna mutant.

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21 January 2018

Microtubule binding and clustering of human Tau-4R and Tau-P301L proteins isolated from yeast deficient in orthologues of glycogen synthase kinase-3beta or cdk5.

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21 January 2018

Serine-409 phosphorylation and oxidative damage define aggregation of human protein tau in yeast

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21 January 2018

Adsorption of Amyloid β (1-40) Peptide at Phospholipid Monolayers

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21 January 2018

Protein aggregation propensity is a crucial determinant of intracellular inclusion formation and quality control degradation

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29 October 2018

PEMT G523A (V175M) is associated with sporadic Alzheimer's disease in a Chinese population.

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29 October 2018

Validation of folate in a convenient yeast assay suited for identification of inhibitors of Alzheimer's amyloid-beta aggregation.

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29 October 2018

Rapid protein-folding assay using green fluorescent protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116298

29 October 2018

Characterization of beta-amyloid peptide precursor processing by the yeast Yap3 and Mkc7 proteases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116298

29 October 2018

First-order kinetic model of Alzheimer's beta-amyloid fibril extension in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116298

29 October 2018

Proteolytic processing and secretion of human beta-amyloid precursor protein in yeast. Evidence for a yeast secretase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116298

29 October 2018

Amyloid-β aggregation on model lipid membranes: an atomic force microscopy study

1 reference

https://pubmed.ncbi.nlm.nih.gov/24870034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of inositol stereoisomers to model amyloidogenic peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/24870034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis and manipulation of yeast mitochondrial genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24870034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/24870034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of Alzheimer beta-amyloid peptide(1-40) with lipid membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24870034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol and inositol involvement in Alzheimer amyloid-beta fibril growth and arrest

1 reference

https://pubmed.ncbi.nlm.nih.gov/24870034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and isolation of a hyperphosphorylated, conformationally changed intermediate of human protein tau expressed in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/24870034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E13-04-0216

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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